ID A0A1S3ICG9_LINUN Unreviewed; 1921 AA.
AC A0A1S3ICG9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Anaphase-promoting complex subunit 1 {ECO:0000313|RefSeq:XP_013395937.1};
GN Name=LOC106163017 {ECO:0000313|RefSeq:XP_013395937.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013395937.1};
RN [1] {ECO:0000313|RefSeq:XP_013395937.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_013395937.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the APC1 family.
CC {ECO:0000256|ARBA:ARBA00010547}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_013395937.1; XM_013540483.1.
DR STRING; 7574.A0A1S3ICG9; -.
DR EnsemblMetazoa; XM_013540483.1; XP_013395937.1; LOC106163017.
DR GeneID; 106163017; -.
DR KEGG; lak:106163017; -.
DR InParanoid; A0A1S3ICG9; -.
DR OrthoDB; 180933at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR GO; GO:0005680; C:anaphase-promoting complex; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR024990; Apc1.
DR InterPro; IPR048971; Apc1_3rd.
DR InterPro; IPR041221; APC1_C.
DR InterPro; IPR046794; Apc1_MidN.
DR InterPro; IPR049255; Apc1_N.
DR InterPro; IPR011989; ARM-like.
DR PANTHER; PTHR12827:SF3; ANAPHASE-PROMOTING COMPLEX SUBUNIT 1; 1.
DR PANTHER; PTHR12827; MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER; 1.
DR Pfam; PF12859; ANAPC1; 1.
DR Pfam; PF21282; APC1_3rd; 1.
DR Pfam; PF18122; APC1_C; 1.
DR Pfam; PF20518; Apc1_MidN; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000085678};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1506..1528
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1540..1561
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 64..185
FT /note="Anaphase-promoting complex subunit 1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12859"
FT DOMAIN 662..977
FT /note="Anaphase-promoting complex subunit 1 middle"
FT /evidence="ECO:0000259|Pfam:PF20518"
FT DOMAIN 1610..1695
FT /note="Anaphase-promoting complex subunit 1 beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF21282"
FT DOMAIN 1729..1875
FT /note="Anaphase-promoting complex subunit 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18122"
FT REGION 280..344
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 516..537
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1921 AA; 213008 MW; B3F615C1CCADC820 CRC64;
MIGAYQAQEF EPYGRGHVAA HPGKVQLQIK KSSTLEHGIP LVKAIKDISL HENSKKEHWH
KRKNVTNNCI EELYIKESTV VWSRGGNEES RKVIKTVTVD SAVQQALWCT FTLPDSLSDV
EQKSNTLDMI GHKEHGICIV ESGCVNVFTD EGKDYISTLP FQVSGAWVIK NGLMFERTVT
HREMANSKRV TPLPVLFTML HPLDELAPVI SKSTGGMNAS KVQFVTSHSH QIVFTSEDPS
LAVLYDTVHG VHSIWKIRRA KLEEGFSASG MDLMGSLPVQ SAATTPLPGH SHSSSSSSLS
RVTFSSLSPS SSMSPFRSHP SRVNSPASRS ISSPSLTQSA SLNQMQSPSV ASNSLYRFQT
PSPGVRSPAC LSRTPVTHNT TLWNDTCAEA GEPLTPDVCL EQVWTDLGIT GGRRHSGRAS
KVFITTDLRE QQYLCYLIPT EKQLRCLKFE ESNDRSQLIF GTALTIPARD AGPLETLNMM
VVLDPGSNLV LYTGTTQVNS IHVPGIPLAT PSTSLSYPPV PDSPARGPFS SSRPPSAMDT
GFEEEVNLLS PVPTEFNESS QLLDGSLAEE LSSWQFPSII AGIKDPVENQ FTVELANGQL
FHTGLPDLAE SPLVRLCLKA VSQVLPRDVG IQVLVKWYAV RNAAGIVSSQ SEWTKFVKCM
FNLMGYDAGK LALTKKYNMD SSASPVMTTK KARTSDHGTE EDWQYLLSSD HHKLSQNTHS
YSLGVEEAIP LQSPSLSCHT VGTADVQALL FSHIPAVMFA LHLAYENAKL NRLLSEELKS
IATVLHQLSR DLKCEAYIDH YCRDFPHLFN VLQERSQFSS ENLQKMHRPH FFSVNPPSIY
RWLYQVLKGA EPDVFPYLPN VTLSVRNIVI LFTVLCTNSG QEPDKEKYLK KIAAAGHRPT
STNVSLSKSF AGSSQASIST NILQLMTELG ITFESIENLL LGVALPLREA IYHGRETPPS
TLPEEAYQLI GREDLAKQVH CEHTPYTAPP GSHETSAKNV REDEDGMNNL DKELLRLRFN
EDHRIQEVRK LLRSSKPVKI MLTQKPEVSD HDFIEEQSRH LYSICIRTMA LPLGRGMFTL
STYHPVVTET LPIPKLCLTG RVPPRNTTID LSHIETPANM NVWPQFHNGV AAGLKIANSS
QVDSTWIIYN KPKSNELTNE HAGFLMALGL NGHLSNLATM NVHDYLCRGH DMTGVGLLLG
IAAAKRGTMD HATVRLLSIH IAAMLPPTST ELDVPHVVQV SAILGMGLVY QGTAHRHVAE
VLLAEIGRPP GPEMDNATDR ESYSLASGLA LGMVMLGRGS ETLGLSDLNM ADQLYHFMVG
GHKRPMTGLN KERYKSPSYQ IKEGDAVNVN VTSPGATLAL GMMFFKSNNS AVAQWLMAPD
TQFLLDFVRP DFLMLRVISQ GLVLWDSVLP SKLWIEQNIP QVIKMYAFNR DKYQNDPTCD
TDFETMSQAY CNIVAGGCMA IALKFAGSAN QEAFECLLDY AKVFIQYLNT ASSIEQAGKS
SLESCLIVVV LSLAMVMAGT GHLEVLRICR LLRTRVGPSY NYVLYGSHMA VSMAVGLLFL
GGGRYTLSTK PEAVAAMLCA FFPKFPNHSN DNRYHLQAFR HLYVLAADSR ILIPRDVDTG
CPSYVPLQIT VKPSSSCPPK EYQVMAPCLL PELNQLQQVV VTGERYWPVS FCADQNWNKL
QHILSTSGTL YVKQRAGHLT YMEDPKGYHS LLAKSFVSDK GGHQRVQPEV IKSFTSDARI
LSFTESFCKE HSDQEYPQTS MLSSLLHECV TQEKPEMLSM YIELHQIIGS LSQGLDSMKC
WQVKLALALY RRFGSERRLL ATEFLLAAES KINVIFEEWL KGHPSSVAKY FSSHQCDEFV
DATFLGTFLV WHDLPLPGYF QNQDLKALQE FPQFYSEYKQ TGLSIGSLLK LFNVLRGCHP
S
//
