ID A0A1S3IDV9_LINUN Unreviewed; 455 AA.
AC A0A1S3IDV9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=ETS domain-containing protein Elk-3 {ECO:0000313|RefSeq:XP_013396041.1};
GN Name=LOC106163090 {ECO:0000313|RefSeq:XP_013396041.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013396041.1};
RN [1] {ECO:0000313|RefSeq:XP_013396041.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=26383154;
RA Luo Y.J., Takeuchi T., Koyanagi R., Yamada L., Kanda M., Khalturina M.,
RA Fujie M., Yamasaki S.I., Endo K., Satoh N.;
RT "The Lingula genome provides insights into brachiopod evolution and the
RT origin of phosphate biomineralization.";
RL Nat. Commun. 6:8301-8301(2015).
RN [2] {ECO:0000313|RefSeq:XP_013396041.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019}.
CC -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC ECO:0000256|RuleBase:RU004019}.
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DR RefSeq; XP_013396041.1; XM_013540587.2.
DR AlphaFoldDB; A0A1S3IDV9; -.
DR STRING; 7574.A0A1S3IDV9; -.
DR EnsemblMetazoa; XM_013540587.2; XP_013396041.1; LOC106163090.
DR GeneID; 106163090; -.
DR KEGG; lak:106163090; -.
DR InParanoid; A0A1S3IDV9; -.
DR OrthoDB; 2884081at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000418; Ets_dom.
DR InterPro; IPR046328; ETS_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11849; ETS; 1.
DR PANTHER; PTHR11849:SF133; ETS DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00178; Ets; 1.
DR PRINTS; PR00454; ETSDOMAIN.
DR PRINTS; PR01217; PRICHEXTENSN.
DR SMART; SM00413; ETS; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR PROSITE; PS50061; ETS_DOMAIN_3; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW Nucleus {ECO:0000256|RuleBase:RU004019};
KW Reference proteome {ECO:0000313|Proteomes:UP000085678}.
FT DOMAIN 58..138
FT /note="ETS"
FT /evidence="ECO:0000259|PROSITE:PS50061"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 247..351
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 247..272
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 273..298
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 304..347
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 455 AA; 50469 MW; 4F10D495C4BC1043 CRC64;
MYNTGMEDLS RYSASPATDS NCSSTFEPAA KRQKVEHYDS SELLSSSSIV KKGMDSNITL
WQFLLELLLS GQHNDIIQWT GNEGEFKLLN AEEVAKLWGL RKNKQNMNYD KLSRALRYYY
DKNIIKKVMG QKFVYKFVSF PETIKTENKI PFKVKMESLA TEGFRSLPGF MTFRPYDIKQ
NLTKQQPQIP TPVSQWQTSP SPIVSQPATY MHVPTPVRNF STANNEIKFT EVKFTPNMEM
KYLPQQPQYR SSPQPVAQPQ RSLNTTPQPA QQMAPPSNTP SPKPPSAAPS PARAVPSPAR
NSPSPARMPV QSIAASQPVA PSPLLSSQPQ CAKTSQSNAS TSVNRPKPQP IEIPKTSIPS
FPMYSPRHPL QSLTTPLLLA SPLQRTPYGP ITFWSSLSPV TSTLSPRFNS PTQFNFPGFV
NGHVALSPVV TGQPFTSAFE NLGSPLFVSS PMPVS
//
