GenomeNet

Database: UniProt
Entry: A0A1S3IFV8_LINUN
LinkDB: A0A1S3IFV8_LINUN
Original site: A0A1S3IFV8_LINUN 
ID   A0A1S3IFV8_LINUN        Unreviewed;      3211 AA.
AC   A0A1S3IFV8;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   05-JUN-2019, entry version 16.
DE   SubName: Full=laminin subunit alpha-2 isoform X3 {ECO:0000313|RefSeq:XP_013397033.1};
GN   Name=LOC106163871 {ECO:0000313|RefSeq:XP_013397033.1};
OS   Lingula unguis.
OC   Eukaryota; Metazoa; Lophotrochozoa; Brachiopoda; Linguliformea;
OC   Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX   NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013397033.1};
RN   [1] {ECO:0000313|RefSeq:XP_013397033.1}
RP   IDENTIFICATION.
RC   TISSUE=Gonads {ECO:0000313|RefSeq:XP_013397033.1};
RG   RefSeq;
RL   Submitted (APR-2018) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00122}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   RefSeq; XP_013397033.1; XM_013541579.1.
DR   GeneID; 106163871; -.
DR   OrthoDB; 128982at2759; -.
DR   Proteomes; UP000085678; Genome assembly.
DR   GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0030155; P:regulation of cell adhesion; IEA:InterPro.
DR   GO; GO:0030334; P:regulation of cell migration; IEA:InterPro.
DR   GO; GO:0045995; P:regulation of embryonic development; IEA:InterPro.
DR   Gene3D; 2.60.120.1490; -; 1.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR000742; EGF-like_dom.
DR   InterPro; IPR009254; Laminin_aI.
DR   InterPro; IPR010307; Laminin_dom_II.
DR   InterPro; IPR002049; Laminin_EGF.
DR   InterPro; IPR001791; Laminin_G.
DR   InterPro; IPR000034; Laminin_IV.
DR   InterPro; IPR008211; Laminin_N.
DR   InterPro; IPR038684; Laminin_N_sf.
DR   Pfam; PF00052; Laminin_B; 2.
DR   Pfam; PF00053; Laminin_EGF; 17.
DR   Pfam; PF00054; Laminin_G_1; 4.
DR   Pfam; PF02210; Laminin_G_2; 1.
DR   Pfam; PF06008; Laminin_I; 1.
DR   Pfam; PF06009; Laminin_II; 1.
DR   Pfam; PF00055; Laminin_N; 1.
DR   SMART; SM00181; EGF; 9.
DR   SMART; SM00180; EGF_Lam; 17.
DR   SMART; SM00281; LamB; 2.
DR   SMART; SM00282; LamG; 5.
DR   SMART; SM00136; LamNT; 1.
DR   SUPFAM; SSF49899; SSF49899; 5.
DR   PROSITE; PS01248; EGF_LAM_1; 8.
DR   PROSITE; PS50027; EGF_LAM_2; 17.
DR   PROSITE; PS50025; LAM_G_DOMAIN; 5.
DR   PROSITE; PS51115; LAMININ_IVA; 2.
DR   PROSITE; PS51117; LAMININ_NTER; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000085678};
KW   Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00122,
KW   ECO:0000256|SAAS:SAAS00814887};
KW   Laminin EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00460,
KW   ECO:0000256|SAAS:SAAS00580772};
KW   Reference proteome {ECO:0000313|Proteomes:UP000085678};
KW   Repeat {ECO:0000256|SAAS:SAAS00814929};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     21       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        22   3211       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5010251814.
FT   DOMAIN       27    279       Laminin N-terminal. {ECO:0000259|PROSITE:
FT                                PS51117}.
FT   DOMAIN      280    336       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN      337    403       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN      404    457       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN      458    506       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN      527    720       Laminin IV type A. {ECO:0000259|PROSITE:
FT                                PS51115}.
FT   DOMAIN      754    803       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN      819    864       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN      865    916       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN      917    963       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN      964   1011       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN     1012   1060       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN     1061   1108       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN     1109   1155       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN     1156   1201       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN     1202   1259       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN     1271   1469       Laminin IV type A. {ECO:0000259|PROSITE:
FT                                PS51115}.
FT   DOMAIN     1512   1561       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN     1562   1620       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN     1621   1674       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN     2221   2414       LAM_G_DOMAIN. {ECO:0000259|PROSITE:
FT                                PS50025}.
FT   DOMAIN     2424   2606       LAM_G_DOMAIN. {ECO:0000259|PROSITE:
FT                                PS50025}.
FT   DOMAIN     2611   2783       LAM_G_DOMAIN. {ECO:0000259|PROSITE:
FT                                PS50025}.
FT   DOMAIN     2854   3026       LAM_G_DOMAIN. {ECO:0000259|PROSITE:
FT                                PS50025}.
FT   DOMAIN     3031   3207       LAM_G_DOMAIN. {ECO:0000259|PROSITE:
FT                                PS50025}.
FT   REGION     2817   2839       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A1S3IFV8}.
FT   COILED     1881   1901       {ECO:0000256|SAM:Coils}.
FT   COILED     1932   1952       {ECO:0000256|SAM:Coils}.
FT   COILED     1967   1987       {ECO:0000256|SAM:Coils}.
FT   COILED     2080   2100       {ECO:0000256|SAM:Coils}.
FT   COILED     2189   2223       {ECO:0000256|SAM:Coils}.
FT   COMPBIAS   2817   2838       Polar. {ECO:0000256|MobiDB-lite:
FT                                A0A1S3IFV8}.
FT   DISULFID    302    311       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    374    383       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    433    442       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    477    486       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    773    782       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    835    844       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    889    898       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    917    929       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    919    936       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    938    947       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    964    976       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    966    983       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    985    994       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1012   1024       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1014   1031       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1033   1042       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1061   1073       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1063   1080       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1082   1091       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1128   1137       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1156   1168       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1158   1175       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1177   1186       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1202   1214       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1230   1239       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1531   1540       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1591   1600       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1621   1633       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1623   1640       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1642   1651       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   2579   2606       {ECO:0000256|PROSITE-ProRule:PRU00122}.
FT   DISULFID   2756   2783       {ECO:0000256|PROSITE-ProRule:PRU00122}.
SQ   SEQUENCE   3211 AA;  352536 MW;  A9B59451CC47BFCD CRC64;
     MVQQAYYWLL ILLGVSGYTC GQLFEHKHEG KFPVIFNLAT EADITSNATC GETGPETYCK
     LVEHVKQLMM KNYQCGICDA NGDLPYQRHP IQNAIDGSNR WWQSPSLANG WQYDWVTITL
     DLGQAFQIAY VIVKAANSPR PANWILERSV DGITFTPWQY FALSDGECWN AFGVPPTVGR
     PRYRRDDEVI CTSFYSRLDP IENGEIHTSL VNGRPGAVNG PSDLLLEFTT ARFLRLRLQK
     IRTLNADLMT IRTSNPDKID KAVTRRYFYS IKDISIGGQC KCYGHASSCP RSPDTGKLMC
     VCEDNTCGKN CEKCCPKFNQ QPYKPGTYRQ RSLCEECQCF GHSDECYYNQ TVADNRQSQN
     IAGEKNGGGV CMNCRDHTTG VNCEQCEAGY YRTTDDPREP CQPCQCSQLG STGTCVQDNS
     RRGEGLMPGD CICRVGFGGR NCDRCASGYK NFPSCIPCPC SRAGSRNVDT CQGDCICKPN
     VVGENCDQCK PGFFNMEASN PAGCMQCFCF GISQNCRSAG WGQSQISSLE GWRVTDLRGK
     KYVVPSLENG RLTVDHDNTE VAGLNPVYYW HAPAPYAGSK ANFLGNKLAS YGGNLTYSMY
     YVVQRLEDVN TAYTADLDVI MEGNELLIGY GGRYYREGLE NTMQVFLTER DWYHVDPDTG
     LPKQQIVTRQ EFMTVLANIE RLLIRASYHI HQTQIQFLDM AMDVAVENST SPSIMSSVEQ
     CFCPRGYSGL SCEVCERGHR RVNDVLYGGI CEQCNCNNHA DTCEASSGLC TSCRDNTVGP
     HCENCEFGYY GNATRGTPND CRPCACPLAI STNNFASNCM AAPPGSQEEY FCVSCPDGYI
     GNHCEMCDDG YFGNPLVPGN YCQPCACSGN INPNAVGNCD RTTGQCLKCL FNTEGWNCAQ
     CKPDYYGMVY GKGCKECDCN QYGSTGTSCD QRSGQCSCRP YYEGRACDSC VAGYGNIIAG
     CPRCSCNLTG SVSNLCDQVS GQCPCKNGVG GQYCGSCLPD HWEYSEEGCK ACNCHLKGSN
     DSQCDLVTGT CTCQPNVIGD KCDQCEINYY DLDSGNGCQS CDCDVTGSTS LQCGMTSGQC
     PCKPGVTGQK CDQCRPGYYG FSSNGCTECP VCPVAGQVCD AVTGECVCPT NTEGDRCERC
     VPDTWGHDQL LGCKQCNCNM TGSLDTQCDT VDGQCECRPE YDGMKCDMCR FGHFGFPNCR
     PCHCNENGTV MSDCNAKGHC QCQEDGQCPC RGNVEGLKCK HCKEGSFSLQ SNNPEGCTSC
     FCFGKSNICE QAQLTWNMTE MPTRSVRVQL DGVSVTTIEP ALHVIPPDAD AIFVTSPDEE
     RPLYWSAPRK FLGDKTLSYY GKLKFVIYFE DQDSLNTLPI PIVDHSEYRR FPLVRITGNF
     RVVLDYFAPL TPGVENEFEI FLREDQWTDP LQPSKPVTRE MLMVGLQNLQ SIKIRASGNS
     NLKYAEIRGL SLQHATNASA GEAALGVERC QCPPEYAGHS CQDPAPGYFR FFPSSNLEEP
     ELIKLLGISK PCECHGHSDM CNKETGVCLN CAHNTAGDHC NTCAEGYYGN ATSGREDACQ
     PCGCPRLEPQ NNFSPTCVTN ATADGYVCNA CPRGYEGDHC ERCSDYFYGD PTKLGGECVP
     CDCSEDGSLD NLCDRESGQC ICHPGVLGRA CDQCQPRYAV VNGRCKSCDV GCTRDLMVAV
     DEMEVMVRGV NTSTMVVIPW ERFFAMENKT QVLRGKLDAI RKVKVGDMEV IVKELQANAT
     KLYTQTSSMA NDAMGYSMVA SNLSKTADGM EKEIREIITS ARDLLDNLPD VHQLSGNVNL
     TSVMMKAQDI MKMIRERDFK PNIENADNEL ELAKALKSSI SDLQSKLTNV TDAAISIQEL
     ADRLNDLISL AEQSAKDSRA ALELNQKNDE LIKKLQNMTQ ALQTRALAVS SMLNMSSEML
     KEANMTLPNS SAEFLRDLLE QLKKDTENLT IAAGLLRQNL PNLEPKVRQA EELAEKLRMQ
     ADNLDNMFQG ARATSEDAVK AAQVYEGIVV AVDDALKEAQ SAHDLASEAM NKTTTADGST
     LQEKAKKSAN TSLDFVNEAN RLVNSSKDLK DLLGSIDKDI DQANKRMDEV DSAKERLTEG
     MDRLPAGIHE KLIEANDNAT GALEKAMNTV TSVDSIQEGL DNDLKPKLDV VKVNTKELQD
     LETMTGTMME INNNLDGIRD VNRSIHTTLG ALNRLNMSLS QSLEELRESI QKAREQANNI
     KVSLAAGGSC HREYRTEELK PSTTNTISFN FKTNNTEKDM LLFYVQGEEK PEFMAVEIVE
     RKLRFVWNSG GGVAMANHSL QIESEETSIQ PDEKWYSVIA RRTANVGTLA VQKIKFAGND
     DPALASSSSS AQFTKLDLND RAKLYVAGAP QGTVERDPAL KGGMFVGCIA DVTLDGRVIG
     LHNFNQSFGE CGMCTESPTP VAPKDISQFD GTGYAEVPPI QRYDSTGYLA LFEFRTFWED
     ALLFFSGNKA NGEYIAVELV NGKVVFSVNF GGGNNISIES REKYNTNQWM TVKAETQGNA
     GQLEVTTSEG REELKRAQAT ASGEDSLDIS NASVYFGGIP STSKFDSFPL SVRTPFLGCM
     KGIQVTAGGN ALPLYKGLSI GMTLGCRENK TRVAGFHGDG YIQLTGDSLP GREADISFSF
     RSLQDIALLL LGLGGQADPH FYSVSLIDGK LQAKFDAGDG EVTITSDDTF NDGMLHGVSI
     IRNRRKLDMF VDDLPVGTER LSKGSKVEIS SLYLGGVPAD LDIASASATS QPLQGCIRDL
     VLNGKLVQLD QPVSYQRADI GRCSENIFSL PLPNVTTTTS TTSATTKPIP IKDTTTTTVS
     TTTTMSTSTT TMSTTTAEPE ECAYEPEPEI EPEAAAFGDV RNSHSEILVD RDEISSNFDI
     MLEFRTYYPN GLLVYLSNED QSEYVAIQMA GGTVMTSYAD QKTGVPVNLT EGATVLVDDG
     KWHKIRLMKS ANNIIFKVDE GPDIVGRIAN KIDVLAPMYV GGLPRGYNMR MGLVPDSLKG
     CVRGFRLNSQ KVDLIQSKAI MGVSTCNKYY EKGVYFSGYA YGIYDSNFVV GSNFLLTFDF
     RTTKPEGVIL TISHPYRRPS MALELFDGQL QFTVNNEDGL IFSMTEYENP FRLCNNKWHT
     VRAELVKNTI MLTVDGVEQL SETGGSEFLA TDHPLFIGGY PYYAEPQGAA QANEKFQGCI
     RNMKINGAEV DWSSSKVLTV DVKIGYCPGT K
//
DBGET integrated database retrieval system