ID A0A1S3II78_LINUN Unreviewed; 203 AA.
AC A0A1S3II78;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 2.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Neurogenic locus notch homolog protein 3 {ECO:0000313|RefSeq:XP_013397945.2, ECO:0000313|RefSeq:XP_023931958.1};
GN Name=LOC106164546 {ECO:0000313|RefSeq:XP_013397945.2,
GN ECO:0000313|RefSeq:XP_023931958.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013397945.2};
RN [1] {ECO:0000313|RefSeq:XP_013397945.2, ECO:0000313|RefSeq:XP_023931958.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_013397945.2,
RC ECO:0000313|RefSeq:XP_023931958.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_013397945.2; XM_013542491.2.
DR RefSeq; XP_023931958.1; XM_024076190.1.
DR STRING; 7574.A0A1S3II78; -.
DR EnsemblMetazoa; XM_013542491.2; XP_013397945.2; LOC106164546.
DR EnsemblMetazoa; XM_024076190.1; XP_023931958.1; LOC106164546.
DR KEGG; lak:106164546; -.
DR OrthoDB; 2968371at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 3.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR PANTHER; PTHR12916; CYTOCHROME C OXIDASE POLYPEPTIDE VIC-2; 1.
DR PANTHER; PTHR12916:SF4; NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1-RELATED; 1.
DR Pfam; PF00008; EGF; 1.
DR Pfam; PF07645; EGF_CA; 1.
DR Pfam; PF12661; hEGF; 1.
DR PRINTS; PR00010; EGFBLOOD.
DR SMART; SM00181; EGF; 2.
DR SMART; SM00179; EGF_CA; 3.
DR SUPFAM; SSF57196; EGF/Laminin; 3.
DR PROSITE; PS00010; ASX_HYDROXYL; 2.
DR PROSITE; PS00022; EGF_1; 2.
DR PROSITE; PS01186; EGF_2; 2.
DR PROSITE; PS50026; EGF_3; 3.
DR PROSITE; PS01187; EGF_CA; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000085678};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 75..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 103..139
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 141..177
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 179..203
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 129..138
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 167..176
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 203 AA; 21976 MW; 2F9948324B6204FA CRC64;
MAGRRGIELF TIPQNQGTAY LNATYGTSLD VALTPEETAS VFESLRTLHP TDNADDPNIN
ITQPPKIKFN KRLQIALVLV GIIYAALVAV VVWSLVHTQE EKMANHCLSN PCKNGATCEN
SVASFMCSCS SGFQGTWCEN DINECINNPC SRGATCRNNN GSFDCDCPPG FTGTLCQLEI
SECSSRPCQN GGTCVDMVNS YRC
//
