ID   A0A1S3IRI2_LINUN        Unreviewed;      1072 AA.
AC   A0A1S3IRI2;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Exportin-1 {ECO:0000313|RefSeq:XP_013400816.1, ECO:0000313|RefSeq:XP_013400817.1};
GN   Name=LOC106166719 {ECO:0000313|RefSeq:XP_013400816.1,
GN   ECO:0000313|RefSeq:XP_013400817.1};
OS   Lingula unguis.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC   Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX   NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013400817.1};
RN   [1] {ECO:0000313|RefSeq:XP_013400816.1, ECO:0000313|RefSeq:XP_013400817.1}
RP   IDENTIFICATION.
RC   TISSUE=Gonads {ECO:0000313|RefSeq:XP_013400816.1,
RC   ECO:0000313|RefSeq:XP_013400817.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the exportin family.
CC       {ECO:0000256|ARBA:ARBA00009466}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_013400816.1; XM_013545362.1.
DR   RefSeq; XP_013400817.1; XM_013545363.2.
DR   STRING; 7574.A0A1S3IRI2; -.
DR   EnsemblMetazoa; XM_013545362.1; XP_013400816.1; LOC106166719.
DR   EnsemblMetazoa; XM_013545363.2; XP_013400817.1; LOC106166719.
DR   GeneID; 106166719; -.
DR   KEGG; lak:106166719; -.
DR   OrthoDB; 169519at2759; -.
DR   Proteomes; UP000085678; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0005049; F:nuclear export signal receptor activity; IEA:InterPro.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006611; P:protein export from nucleus; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR041123; CRM1_repeat.
DR   InterPro; IPR041235; Exp1_repeat_2.
DR   InterPro; IPR013598; Exportin-1/Importin-b-like.
DR   InterPro; IPR001494; Importin-beta_N.
DR   InterPro; IPR045065; XPO1/5.
DR   InterPro; IPR014877; XPO1_C_dom.
DR   InterPro; IPR040485; XPO1_repeat_3.
DR   PANTHER; PTHR11223; EXPORTIN 1/5; 1.
DR   PANTHER; PTHR11223:SF2; EXPORTIN-1; 1.
DR   Pfam; PF08767; CRM1_C; 1.
DR   Pfam; PF18777; CRM1_repeat; 1.
DR   Pfam; PF18784; CRM1_repeat_2; 1.
DR   Pfam; PF18787; CRM1_repeat_3; 1.
DR   Pfam; PF03810; IBN_N; 1.
DR   Pfam; PF08389; Xpo1; 1.
DR   SMART; SM01102; CRM1_C; 1.
DR   SMART; SM00913; IBN_N; 1.
DR   SUPFAM; SSF48371; ARM repeat; 2.
DR   PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Reference proteome {ECO:0000313|Proteomes:UP000085678};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          46..112
FT                   /note="Importin N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50166"
FT   REGION          1046..1072
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1072 AA;  123037 MW;  2EAC4A5494F68430 CRC64;
     MPPASMTALT EQATKLLDFN QKLDINLLDH VVGCMYSGEG QTQRVAQEVL TTLKEHPDAW
     TRVDTILEYS NNQQTKYYAL QILENVIKTR WKVLPRTQCE GIKKYIVGLI IKTSSDPETL
     EREKVYLGKL NMILVQILKY EWPKNWPSFI YDIVGASKTN ESLCQNNMAI LKILSEEIFD
     FSSGQMTQAK AKHLKDSMCT EFAQIFTLCQ FVLDNSQNAP LVGSTLDTLM RFLTWIPLGY
     IFETKLITTL IYKFLNVPMF RNVTLKCLTE IAGVSVTQYD EQFLQLFNLT MTQLKQMLPT
     STNIKDAYAH GQDDEQKFIQ NLSLFLCTFL KEHGTLVEKK QELHDVLMEA LHYLILISEV
     EETEIFKICL EYWNTLAADL YRESPFSASQ TPLLIGRMAD VPPSRRALYT PVLSKVRRVM
     ISRMAKPEEV LVVENEQGEV VREFMKDTDS INLYKNMRET LVYLTHLDYQ DTENIMTEKL
     TNQVNGTEWS WKNLNTLCWA IGSISGAMHE EDEKRFLVTV IKDLLGLCEQ KRGKDNKAII
     ASNIMYVVGQ YPRFLRAHWK FLKTVVNKLF EFMHETHDGV QDMACDTFIK IAQKCRRHFV
     QVQVGEVMPF IEEILNSINT IICDLNPQQV HTFYEAVGLM ISAQTDQGAQ EHLVEKYMML
     PNQVWDTIIN QATQNVEVLK DPEAVKQLAN ILKTNVRACK ALGHPYVLQL GRIYLDMLNV
     YKVMSENISI AIATNGENVT KQPLIRSMRT VKKETLKLIS GWVSRSNDSQ MVAENFIPPL
     LEAVLMDYQR NVPLAREPEV LSTMATIVNK LEGSITKDVP QIFDAVFECT LEMINKDFEE
     FPEHRTNFFL LLQAVNSHCF PAFLAIPPAQ FKLVLDSIIW AFKHTMRNVA DMGLSIMYTL
     LQNVGQEENA AQSFYQTYFT DILQHIFSVV TDSSQSGGLT MHASILAYMF TLVEMGKITV
     SLSPNHQASQ NVQFVQEFLV NLLKAAFPHL NDTQLRVFIE GLFSFDQDIQ AFKEHLRDFL
     VQIREFAGED NSDLFLEERE SAIREAQDEK RKQQMAVPGI LGPHEVTEDM QD
//