ID A0A1S3IVN2_LINUN Unreviewed; 5251 AA.
AC A0A1S3IVN2;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=HECT-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012485};
DE EC=2.3.2.26 {ECO:0000256|ARBA:ARBA00012485};
GN Name=LOC106167903 {ECO:0000313|RefSeq:XP_013402252.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013402252.1};
RN [1] {ECO:0000313|RefSeq:XP_013402252.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_013402252.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.26; Evidence={ECO:0000256|ARBA:ARBA00000885};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR RefSeq; XP_013402252.1; XM_013546798.2.
DR STRING; 7574.A0A1S3IVN2; -.
DR EnsemblMetazoa; XM_013546798.2; XP_013402252.1; LOC106167903.
DR GeneID; 106167903; -.
DR KEGG; lak:106167903; -.
DR InParanoid; A0A1S3IVN2; -.
DR OrthoDB; 5491782at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000085678; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd08664; APC10-HERC2; 1.
DR CDD; cd00078; HECTc; 1.
DR Gene3D; 2.30.30.30; -; 1.
DR Gene3D; 3.30.60.90; -; 1.
DR Gene3D; 3.10.120.10; Cytochrome b5-like heme/steroid binding domain; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.30.2160.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.30.2410.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.90.1750.10; Hect, E3 ligase catalytic domains; 1.
DR Gene3D; 2.130.10.30; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; 4.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR004939; APC_su10/DOC_dom.
DR InterPro; IPR006624; Beta-propeller_rpt_TECPR.
DR InterPro; IPR021097; CPH_domain.
DR InterPro; IPR001199; Cyt_B5-like_heme/steroid-bd.
DR InterPro; IPR036400; Cyt_B5-like_heme/steroid_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR000569; HECT_dom.
DR InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR InterPro; IPR037976; HERC2_APC10.
DR InterPro; IPR010606; Mib_Herc2.
DR InterPro; IPR037252; Mib_Herc2_sf.
DR InterPro; IPR009091; RCC1/BLIP-II.
DR InterPro; IPR000408; Reg_chr_condens.
DR InterPro; IPR014722; Rib_uL2_dom2.
DR InterPro; IPR000433; Znf_ZZ.
DR InterPro; IPR043145; Znf_ZZ_sf.
DR PANTHER; PTHR22870; REGULATOR OF CHROMOSOME CONDENSATION; 1.
DR PANTHER; PTHR22870:SF437; X-LINKED RETINITIS PIGMENTOSA GTPASE REGULATOR-RELATED; 1.
DR Pfam; PF03256; ANAPC10; 1.
DR Pfam; PF11515; Cul7; 1.
DR Pfam; PF00173; Cyt-b5; 1.
DR Pfam; PF00632; HECT; 1.
DR Pfam; PF06701; MIB_HERC2; 1.
DR Pfam; PF00415; RCC1; 21.
DR Pfam; PF00569; ZZ; 1.
DR PRINTS; PR00633; RCCNDNSATION.
DR SMART; SM01337; APC10; 1.
DR SMART; SM01117; Cyt-b5; 1.
DR SMART; SM00119; HECTc; 1.
DR SMART; SM00706; TECPR; 6.
DR SMART; SM00291; ZnF_ZZ; 1.
DR SUPFAM; SSF55856; Cytochrome b5-like heme/steroid binding domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
DR SUPFAM; SSF159034; Mib/herc2 domain-like; 1.
DR SUPFAM; SSF50985; RCC1/BLIP-II; 5.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS51284; DOC; 1.
DR PROSITE; PS50237; HECT; 1.
DR PROSITE; PS51416; MIB_HERC2; 1.
DR PROSITE; PS00626; RCC1_2; 1.
DR PROSITE; PS50012; RCC1_3; 23.
DR PROSITE; PS01357; ZF_ZZ_1; 1.
DR PROSITE; PS50135; ZF_ZZ_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000085678};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786,
KW ECO:0000256|PROSITE-ProRule:PRU00104};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00228}.
FT REPEAT 538..589
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 590..643
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 644..695
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 696..747
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 748..799
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 888..941
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 942..993
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 994..1045
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 1046..1097
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT DOMAIN 2220..2293
FT /note="MIB/HERC2"
FT /evidence="ECO:0000259|PROSITE:PS51416"
FT DOMAIN 3127..3178
FT /note="ZZ-type"
FT /evidence="ECO:0000259|PROSITE:PS50135"
FT DOMAIN 3188..3365
FT /note="DOC"
FT /evidence="ECO:0000259|PROSITE:PS51284"
FT REPEAT 3385..3436
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 3437..3491
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 3492..3543
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 3544..3595
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 3598..3649
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 3650..3701
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 3702..3753
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 4372..4423
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 4424..4477
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 4478..4529
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 4530..4583
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 4584..4635
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 4636..4687
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 4688..4739
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT DOMAIN 4877..5217
FT /note="HECT"
FT /evidence="ECO:0000259|PROSITE:PS50237"
FT REGION 178..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 753..772
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1051..1070
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1273..1293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1662..1686
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1876..1903
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2718..2740
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2816..2838
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2906..2932
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3781..3801
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3865..3884
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4021..4040
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5220..5251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1295..1322
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 179..193
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1672..1686
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2718..2736
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2907..2926
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4023..4038
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5224..5242
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 5180
FT /note="Glycyl thioester intermediate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00104"
SQ SEQUENCE 5251 AA; 574164 MW; 149A9EA2BC46B6F9 CRC64;
MQRAPRLRPQ VRLDTKWLKT DIQAAFSHDG LSQLWNELVK DREIVSDVSD GILNSAGLLA
KKGETGRYYC GAKVLSCACC DSHCGPNNGC NCPACQKLDQ EEKERKEEEA KMPKPSHSII
DSWTWGQQPD SNQLNACLHS LLHEHHQLVS DAAGTTLSAM RLKQRLVVLE RYFTALSRHS
PSEGKSPTRK KQTIQTNMDK KKSSQKPVEK ATMGLARVGS RAALSFAFAF LRRAWRSGED
ADLCSELLQE SLDALRALPE ATLFDESTVS PVWMEVVERA SKFLRSVVAG DLNGAATAKG
SGKVPIQDQQ IALALLLELA VQRGSLSHLL GAVHLLLNLW NNSKYDHDNR SCGLSSAPLV
PLLKRFNEIQ SQKSHSAWDH GKMDESNYSF SPTECFLRYL SIPEDEDMLL DLRQCAVVIV
SHLDRLSGPY NPPQESHKSN SSRVTQEVLG WGWLAWTVGT SKTGPQLVQA LSDLGGIQQI
VCGERALLAL TKTGKVFSLY YTSEAQNVQA VEGFGDKDIV KVVAHPDGKH FMALSSDGDV
FAWGNGDGGR LGLGDNNSRD QPVQINSLSG KHVVNISCGS TYSAAVTADG ELYTWGRGNY
GRLGHGSSED VTVPTLVASL KEHKVVDVAC GSGDAHTLVV TDDGSVFSWG DGDYGKLGRG
GSEGCKSPKL VEKLQGLDIV RVYCGAQCSL ALSKAGAVYS WGKGDNYRLG HGTEEHVRHP
KQLEAMSGKK VVDIAVGPTH CLALTEDGDV YSWGRNDQSQ QGDGHSSTKT DPGVVTHLQG
KHIIGVACGP GQSFAWSSSM QWSVGARVPF VVDLCKSTFE QLDRLLDSVC EGMDGRSDWP
PPQEKECMAV GALNLLSLQP VQINSLSGKH VVNISCGSTY SAAVTADGEL YTWGRGNYGR
LGHGSSEDVT VPTLVASLKE HKVVDVACGS GDAHTLVVTD DGSVFSWGDG DYGKLGRGGS
EGCKSPKLVE KLQGLDIVRV YCGAQCSLAL SKAGAVYSWG KGDNYRLGHG TEEHVRHPKQ
LEAMSGKKVV DIAVGPTHCL ALTEDGDVYS WGRNDQSQQG DGHSSTKTDP GVVTHLQGKH
IIGVACGPGQ SFAWSSSMQW SVGARVPFVV DLCKSTFEQL DRLLDSVCEG MDGRSDWPPP
QEKECMAVGA LNLLSLQLYA AIYQEEDAEN LGLNPGSRLI TSLKQRIIAL ATNSGVIATV
QSAAQSALQN GWSLLLPTAE ERARTLSTLL PTGGSRDMAV LSPGQRFMTD LLVSSLMADG
GLEMALRTAI KKEKEGIEEK TEKDTEKEPD DMDKIGQATN MLKSEEALLE EEAQKCQDIQ
VDGDSSIPLL QLVQQLLRNA STQMLSRLNE LSQDPQVKTE ALDLSDNIAS INLLLQFQRL
LMAKIFPREE FKEKKGSMEI DAELLGAGSL LRKYVHLLVA HVADILPLAA SLAGYSSKYF
SLVAKVISAD VTGVLLPELI TSAVLLQTIS PAVIKASGCI PLLEALLPIL DKFNRLAPGL
EKDDKEDMAW PGIMATSVEK QIQHHLEDVP VVRKSDLENH NKDGGLWIVI HGKVYDVQDF
KAQAQCGEEI LMQYAESARE MMETFFVGQY IDPEHDLIQS TPSNAVSSPL MDTERTLGLL
LGLHASSLAR GTRLSAQEEE SKQWLESEFF AGGLQVLQPQ NPFEEEKGES RTPSSCTTTP
GHTPTSEQKQ LHASLNEKQQ LLEHQDSLAD ASKPFLQSLA DGGLQEHTVQ SFMGYVSRYA
KHHHLVMPIE FPNDHPVEEV ARRLMAVLLK HHDLGHVALG LVEHGLSESG NKFGLPRSIA
EVCKTVFQVK RSLIKIHQDL SRSYKEVCAP VIERCMFLFN ELRPAMGNEV HTMEKSKMLK
SKPRWVEVTK RMIAEKRKVK LASPPSPPQP QASGSADNSS PVHPEDVTLV IKEEDLKLEV
KDMWEVNSSK GQPSSVKCQG VKVHEVKIEE PIGQVMESKD TPRKRRVNEL WDLVYYAVSS
HRERMWLKQR LTGSIVHPTL MTRIVEFVLY EDPIDIEMLR TSLHHQVERA ESRLTGIQNM
LTLVHKDFLI PSVKYNILCG WQGSIAAERK CSDSSINCLS NVNLIPPCDR ILLEMMFSEL
NKWVVKTLRS CIIEADMFFK AHSLPASHTQ DNSKVCVEDI SLGVLPVARF LLATLSLLLT
EHQANGISML INSGLLALTQ SLLRLAGPDL ETIPQQSCNS LCAVLEESQK QKRTQPVPLS
GPELAAMMKV GTRVMRGVDW KWGDQDGPPP SLGRVIGELG EDGWIRVQWD TGSTNSYRMG
KEGKYDLKLA EPPQMSTEED EEEDDDVVAD NERRERKHPT ALLRCVTTQL LKSVAIMTSV
HAEQVLEEAI CTLCGLVRNI VEAGCNSGLN TNSTQILIAR EQYYSWGSLG FISSLAHSPS
LCKALSTHPW IQLLIRILTE DQDPSEPRNL PRQILTLRLL RRVLPAWDSG VDRSKMTEVI
SRLFSLLGHV LMTCDSDPTL TTQDSYSKAS KKIKAPVSLT ASYSSTIAEE VVSLLRCLHG
HDAWNPHINK FLCNQLGTVA ELLTGKQDTT ASSVYKSILA VLAVIGGVDD RVRLGGLATY
EECGLATVSR IHVRGKVTLQ FHENKEIRTF KLSEIKPIKS SRFLVDQLPL TDSLLQIWTK
LVTIMSTTRE KDHMTSLQAS TGPAEGASSA SDMVQLKLLQ IQQLKLGLLK AAIALFSKQE
NLRKILLQPI PVDSVSVQAT SDVDGSSDTG GQEDTSPEIE SGPKFLMQQL MLAATQPSQV
KAVFSRQELE AAALAVCQHL TAQANNPYSS QSQDSLMASS HLSDLGAAAP ASVLDSNTKA
NNEPAPQAPK FTQKPQESQI VARLQKPKRI KPPSPPPVPV VAQLMEMGFV RKRVEMALKA
LEGACAPGAD TPSAETLVGW LLEHHDVQPP SSSSDSDSSV DLCSDSESMS DELEDLDGGY
AEAVAIEPPL PATPYKRRSE FANNDEYAIY LSDHIQVGMM VRCCRTYEEV HEGDIGKVMK
LDSDGLHDLN IQAEWPRKGG LYWVRYIHVE LLGFIPPGQQ IPAVTTGSST AVALPTATQQ
QNIKVGDRVR VKRSVTTPKY RWGSVTHNSI GVVTAISASG KDVTVDFPQQ SHWTGLMAEM
ELVPSAHPGV TCDGCGQFPI MGPRYKCKTC YDFDFCENCF RSKRSHRHAF NRIADPGGPA
IYAGKPSRYR SRFNDSNISG GGTSDSYIDD WHRCVKYLTV SSRENQAHRL IDGSGGCWQS
SGSQGKHWIK LEMQPDLIIT KLTMRVEPSD SSYMPSLVVV SAGDTVHSMK EIRTIHVGQL
DTTVVLLQDM AEYFRFIELS IKQCRSSGID CKIHGLSISG RMRAEEDDMA GNFPFLESDE
EEEEQTTSQQ QTKKVKLSSN KEIQTHVFVW GLNDKDQLGG PKGSKIKMPA LNEFNSSLKC
IQIAGGSKSL FCVTQDGKVY ACGEATHGRL GLGITSGNVS TPRQLVSLSQ YVIKKVAVHS
GGRHALALTV DGKVFSWGEG DDGKLGHFSR FNSDKPKLIE ALRSKRVRDI ACGSSHSAAI
SSNGDLYTWG LGEYGRLGHG DNLTQLRPKQ VKGLAGKRVV QVACGSRDAQ TLALTDEGHV
YSWGDGDFGK LGRGGSEGCS VPRIIERLTG LGVIQIECGA QFSLALTKEG EVWTWGKGDY
FRLGHGTDAH VRKPQLVEGL KGKKIVHVAV GALHCLAVQD QGQVYAWGDN DHGQQGNGTT
TVNKKPALVH GLEGYKITRV ACGSSHSVAW TLTDMSAPSS HEPVMFGTPR DPLGASVVGV
EDSSSEESPV SPTPNNAIGK SSVRPSLTKI ILSQESSYSK QQALKHILTA LQIMYARGAI
VGALTKEPDT VSAVPGLDNW KMTTPASISP VSATPVESPR SLSGSGEQEL QTIQQMAAIA
PIRPEHLPSF HALVAASPTT SILAETVTST EEVAEPEETD HSTSHTDLDD FTAKLTANDA
RMLVDLLKLA VAGRAGAHGK EALSGVLKAL GKTYPQVQEM LLELCVTELE DVAADRESVR
NAAQPVVQES SHPYTDDTSL SGHVKIPGAE ALRVEFDRQC STERRHDPLT IMDASGRTVT
IRSGREWSDW SQELRINSEE LRWKFTSDGS VNGWGWRFTV YPIMPSAAAL ERLSDRTVES
RPSIDLVTCL LDLKLEASMD KTIVTRLAAA LAACAQLSSL GARQRMWALQ KLRELMTTNF
GPMINVSTLM QAPCSPFSDG LDEPRQSSLS GTALASLVKG LPEALQRQYE YEDPIVRSGK
HLMHSSFFKV LVALACDLGL DTLSCCIEMH KWSWFRRYCM AARVAVALQH RTALPQPFCE
EVHKKVMEIA PDDEKIRGHE DHAIFKQEQD EQLLLWLNRH PDDWTLSWGG SGQIWGWGHN
HRGQLGGVEG AKVKLPSSCE ALAQLRPIQV VGGEQTLFAV TADGKVYATG YGAGGRLGIG
GSDSVASPTL LESIQHVFIT KVTVNSGGKH CLALSAEGEV YSWGEGEDGK LGHGNKSPCD
RPRVIESLRG TEVVDIAAGG AHSACITSGG QLYTWGKGRY GRLGHGDSED QLKPKLVEAL
RGYFVQDVAC GSGDAQTLCI TNDGSVWSWG DGDYGKLGRG GSDGCKVPMK IDAMHEVGVI
KVECGSQFSV ALTSTGAVYT WGKGDYHRLG HGTDDHVRRP KRVTAIQGKN VVHIACGSLH
CVCCTDTGEV FTWGDNDEGQ LGDGTTNAIQ RPRLVAALQG KMINRVACGS AHTLAWSTNK
PIQTSRLPSA IPMEYNHLSN IPIPVLRNRL VLLHHFSDLF CPSIPMFDLE GAVEGQQRGP
LLVTDALRGI LVSAAKETSF RKVVQATMIR DRQHGPVIEL NRIQVKRSRS KGGLAGPDGT
KSVFGQMCSK IAAFGPDSLM LPHRVWKVKF VGESVDDCGG GYSESIAEMC DELQNGSTPV
IIVTPNGRDE SGANRDCFLP NPTCKSALHQ SMFKFLGMLI GIAIRTGSPL SLNLAECVWK
QLAGMQLSIT DLQEVDKDYV PGLMCIKDMS EDALSAADMP FSTPSAAGHE VHLKSKFSKI
TTENRNEYVR LALNYRLHEF DDQIHWMREG IARVIPVPLL SLFTGYELET MVCGSPDIPI
NLLKSVATYK GIDATAPLIQ WFWEVMEEFT NQERSLFLRF VWGRTRLPRT IADFRGRDFV
LQVLDKYSPP DHFLPESYTC FFLLKLPRYS CKIVLREKLK YAIHFCKSID TDDYARVALS
GDPMEDDSTD DVQSDDFDSM DSDGDLVYGS E
//
