ID A0A1S3IZ01_LINUN Unreviewed; 363 AA.
AC A0A1S3IZ01;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Probable G-protein coupled receptor 22 {ECO:0000313|RefSeq:XP_013403243.1};
GN Name=LOC106168645 {ECO:0000313|RefSeq:XP_013403243.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013403243.1};
RN [1] {ECO:0000313|RefSeq:XP_013403243.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_013403243.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_013403243.1; XM_013547789.1.
DR AlphaFoldDB; A0A1S3IZ01; -.
DR STRING; 7574.A0A1S3IZ01; -.
DR EnsemblMetazoa; XM_013547789.1; XP_013403243.1; LOC106168645.
DR GeneID; 106168645; -.
DR KEGG; lak:106168645; -.
DR InParanoid; A0A1S3IZ01; -.
DR OrthoDB; 2953289at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR CDD; cd00637; 7tm_classA_rhodopsin-like; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR PANTHER; PTHR24241:SF179; G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24241; NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|RefSeq:XP_013403243.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000085678};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 40..68
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 80..101
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 121..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 160..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 207..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 267..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 305..325
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 59..322
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
SQ SEQUENCE 363 AA; 40461 MW; D32F05C564697341 CRC64;
MLALFFHLQL SPVPLPLEMM GEILNSTDLN LASMGEVPSA YLVVVCFILT VEIVLGVTVN
IMVLWAYYRH WNTLRSVSNI LMANLNVVDI LICVLSAPLT FTTLLLRHRD TDVLVCLSHE
AGVSFACSAT ALNLLVISVD RYESVIMPTK RTFSVKNVRF VLLVPWCGAL LGIGAAFIHT
ANPVLVTYTD VKSCVTWYLT TQTRHYFQTY WVVLFVSSSL WMIVSYRKIV NAAHTRLSIK
AALVQASLVV AGSGFCDKKV RPTGARATKV ALAIVSTYVL CWGPYTTYSL AVMVKPQMTQ
ETINVGLLCL AYMTTILHPI LYAFLRRKVR RACWTLVLAD QRSVRTIQVA PFRHASTRDD
CAT
//
