ID A0A1S3IZN5_LINUN Unreviewed; 493 AA.
AC A0A1S3IZN5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Probable ATP-dependent RNA helicase DDX58 {ECO:0000313|RefSeq:XP_013403655.1};
GN Name=LOC106168943 {ECO:0000313|RefSeq:XP_013403655.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013403655.1};
RN [1] {ECO:0000313|RefSeq:XP_013403655.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_013403655.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_013403655.1; XM_013548201.1.
DR AlphaFoldDB; A0A1S3IZN5; -.
DR STRING; 7574.A0A1S3IZN5; -.
DR EnsemblMetazoa; XM_013548201.1; XP_013403655.1; LOC106168943.
DR GeneID; 106168943; -.
DR KEGG; lak:106168943; -.
DR InParanoid; A0A1S3IZN5; -.
DR OrthoDB; 342391at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0002376; P:immune system process; IEA:UniProt.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR CDD; cd01671; CARD; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR031964; CARD_dom.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR14074:SF16; ANTIVIRAL INNATE IMMUNE RESPONSE RECEPTOR RIG-I; 1.
DR PANTHER; PTHR14074; HELICASE WITH DEATH DOMAIN-RELATED; 1.
DR Pfam; PF16739; CARD_2; 2.
DR Pfam; PF00270; DEAD; 1.
DR SMART; SM00487; DEXDc; 1.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|RefSeq:XP_013403655.1};
KW Helicase {ECO:0000313|RefSeq:XP_013403655.1};
KW Hydrolase {ECO:0000313|RefSeq:XP_013403655.1};
KW Nucleotide-binding {ECO:0000313|RefSeq:XP_013403655.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000085678}.
FT DOMAIN 305..463
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT REGION 465..493
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 472..493
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 493 AA; 56093 MW; 848E2B41B84653F6 CRC64;
MDNSQPREEC DEVGQGDSHI DKFQLQREIL TVCSTVFIDK IQPVELCVHL SDIIGKAEED
KIKAATDEKG PRKGAELLLS FVLESTDPGW FTVFVNGLRE TGSETALGIL EDFKALSDFS
QHVNGMKYDL NSVRFEDLHE KHLRVFRPHI IEYLEPIQLL PHLIQRGVLS NSTVDRIRAE
TRNKGRFYGS LMLLRHLPTL KNTWYTDFLY SLWDSGNQKD KELVQLIDPD FNPDWKQYQT
SQKRTVTKEI AGDTIDAVPP KCRKYGSADE GRNITGAEVE QVSLKLSDLN ITDELSLRNY
QHELAEPALR GQNCIIVAPT GSGKTRVAAH IVAEHLKQGA DRKVVFMACK VPLVQQQYQL
FCQLFEKYEL RVLKVCGDDE SNKFLHQLIS EFDIIVLTPQ ILENHLLENT ISSLDVFSLL
IFDECHHTQK ASVKKTHTSS VTAQDDHPEF SPLTLMLRRL TSEDDQHVQP CYGRSRHSSR
TSSTSDSRDS SEL
//
