ID   A0A1S3J141_LINUN        Unreviewed;       704 AA.
AC   A0A1S3J141;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Uncharacterized protein LOC106169291 {ECO:0000313|RefSeq:XP_013404162.1};
GN   Name=LOC106169291 {ECO:0000313|RefSeq:XP_013404162.1};
OS   Lingula unguis.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC   Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX   NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013404162.1};
RN   [1] {ECO:0000313|RefSeq:XP_013404162.1}
RP   IDENTIFICATION.
RC   TISSUE=Gonads {ECO:0000313|RefSeq:XP_013404162.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_013404162.1; XM_013548708.1.
DR   AlphaFoldDB; A0A1S3J141; -.
DR   STRING; 7574.A0A1S3J141; -.
DR   EnsemblMetazoa; XM_013548708.1; XP_013404162.1; LOC106169291.
DR   GeneID; 106169291; -.
DR   KEGG; lak:106169291; -.
DR   InParanoid; A0A1S3J141; -.
DR   OrthoDB; 5352585at2759; -.
DR   Proteomes; UP000085678; Unplaced.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0002218; P:activation of innate immune response; IEA:InterPro.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.20.5.5200; -; 2.
DR   Gene3D; 3.40.50.12100; Stimulator of interferon genes protein; 2.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 2.
DR   InterPro; IPR029158; STING.
DR   InterPro; IPR038623; STING_C_sf.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   PANTHER; PTHR34339; STIMULATOR OF INTERFERON GENES PROTEIN; 1.
DR   PANTHER; PTHR34339:SF1; STIMULATOR OF INTERFERON GENES PROTEIN; 1.
DR   Pfam; PF13676; TIR_2; 2.
DR   Pfam; PF15009; TMEM173; 2.
DR   SMART; SM00255; TIR; 2.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 2.
DR   PROSITE; PS50104; TIR; 2.
PE   4: Predicted;
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000085678}.
FT   DOMAIN          8..138
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|PROSITE:PS50104"
FT   DOMAIN          366..504
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|PROSITE:PS50104"
SQ   SEQUENCE   704 AA;  80713 MW;  4DDC9D1701E6F1BE CRC64;
     MAEETADYEY DVFISYSFKD SREVEQLSED LKEEGVKCVL AERDFDPGKP VLESIINCFE
     HSRRSLLYIT THSIKSNWCR FEKSLSLAHA VKSEKQQVIP VYANITDEEL EEVPGHLRAL
     DPIDSRKERF FDTLLSRIKA PLVGLKKALP TGNVAHGLVW GYFYGYLNLI LPGLKQRFQE
     WEDFDPHSRK GKYIPKFIIL LPESCYCWSS MNDNDDRIQR AGNLKPFNKA RAGKPEREYK
     NFLFTVTADD GELYYFSGEY STPLMSMQEL ESGHLAEFDA NAKCVQYELY CQVLKQALDS
     ALPEGAKDTY LLLKYQDEME GGSKKYPIAD LIVKAIRDGL NTEASGNTTQ QEHGLPTEFE
     KVKVGEEYDA FVWHSDDDGE EVDRLVEKLE SYGDRQFRII HRGKFEVDKM ETKSIEEALK
     NSRNTILYVT KRFLESTPYL NTLLMHERLT DDIQQGRLTL VPVLVDVEPN ELPSVLTNVI
     YIEKSKMTED ECFGRLVKAL EAPILKLKSA QPAGDIATGM AWSYYYGYLK LILPGLKQRI
     EASNYWTQGG SNTVVIPKLV LLLPQSCYVW DKLQDSDQKI QYVGEVKFRV TRAGLPDRDY
     SSRLYKFQSE SDGKEYVFAS EYATALLHLY EMEKGRSAGL NAKEMMKQQK DFCRILGEIL
     NNAEECLGNF ILLPYDDTNC QFPITKELEK KLKELSDASH QGAT
//