ID A0A1S3J1K8_LINUN Unreviewed; 797 AA.
AC A0A1S3J1K8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Alpha-N-acetylglucosaminidase isoform X3 {ECO:0000313|RefSeq:XP_013404322.1};
GN Name=LOC106169263 {ECO:0000313|RefSeq:XP_013404322.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013404322.1};
RN [1] {ECO:0000313|RefSeq:XP_013404322.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_013404322.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_013404322.1; XM_013548868.1.
DR AlphaFoldDB; A0A1S3J1K8; -.
DR EnsemblMetazoa; XM_013548868.1; XP_013404322.1; LOC106169263.
DR GeneID; 106169263; -.
DR OrthoDB; 1112009at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 1.20.120.670; N-acetyl-b-d-glucoasminidase; 1.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR007781; NAGLU.
DR InterPro; IPR024732; NAGLU_C.
DR InterPro; IPR024240; NAGLU_N.
DR InterPro; IPR024733; NAGLU_tim-barrel.
DR PANTHER; PTHR12872; ALPHA-N-ACETYLGLUCOSAMINIDASE; 1.
DR PANTHER; PTHR12872:SF1; ALPHA-N-ACETYLGLUCOSAMINIDASE; 1.
DR Pfam; PF05089; NAGLU; 1.
DR Pfam; PF12972; NAGLU_C; 1.
DR Pfam; PF12971; NAGLU_N; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000085678};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..797
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010197134"
FT DOMAIN 44..119
FT /note="Alpha-N-acetylglucosaminidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12971"
FT DOMAIN 141..472
FT /note="Alpha-N-acetylglucosaminidase tim-barrel"
FT /evidence="ECO:0000259|Pfam:PF05089"
FT DOMAIN 484..745
FT /note="Alpha-N-acetylglucosaminidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12972"
SQ SEQUENCE 797 AA; 91774 MW; 5F62FD2EE61DD927 CRC64;
MMSTRCAVIL FLLFAPGDRH VTASVEFPTL DHLHTKVPPD IQEAAVKALA TRALGDNAKF
FQFKVDSELG VPNRDSFKLQ TVQNVIHVTG TTGVAAAWGL QYYLKHYQGF HFSWGGDQKT
WRGFRPVPDP GIKITSNDRF RYYQNVCTSS YSFVWWNWTR WEREIDWMAL NGINLPLAFT
GQEAIWQKVY LKLGLSQKDL DEHFAGPAFL AWGRMGNMRG FGGPIPQTWL DNQLKLQHQI
LRRMRELGML PVLPGFAGHI PEGFTRVYPN VNCTRLGGWA GFADPKYCCT YLLDPNDPMF
VKVGQAFIEE MSKEFNGTNH IYNADTFNEM TPSSGALSYI SGAGKAVFKG MESGDPQAIW
LMQAWLFLSS FWNADRAKAL LTSVPQGRMI LLDLRAELYP QYERFESFYG QPFIWCMLHD
FGGGNYMQGQ IEDINQGPFK ARAYPNSSMI GIGLTPEGIN QNDVIYEFMN ENIAREKPVN
TITWFMNYAD RRYGISSLNV QTGWIYLMHS IYNCTDRHDD FSNNNIPTQR PRLSPPIKPD
VWYDPKVVIA AWKYFVSDSS KLKSSDLFRY DLVDVTRQVL QLLGLQYYTI MITAYKSKNA
TLFNTTSGMF IELLTDMDTL LSSDQHFLLG AWIADAHNMA ESEAERKLYE YNARNQVTLW
GPNGEILDYA AKQWGGLVGK YYLPRWLLFI NQLKEALSKG QKFNQTAFNK NVFSQVEQPF
TFDTTPFPVQ PQGDSVQVVR TIFKKYFPST RSKFFKKLKQ FTPHGKKYMK YATRWLKKNP
RVINKLVEKW QRMNTRL
//
