ID A0A1S3J1Y4_LINUN Unreviewed; 904 AA.
AC A0A1S3J1Y4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Malignant fibrous histiocytoma-amplified sequence 1-like {ECO:0000313|RefSeq:XP_013404435.1};
GN Name=LOC106169511 {ECO:0000313|RefSeq:XP_013404435.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013404435.1};
RN [1] {ECO:0000313|RefSeq:XP_013404435.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_013404435.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_013404435.1; XM_013548981.2.
DR AlphaFoldDB; A0A1S3J1Y4; -.
DR STRING; 7574.A0A1S3J1Y4; -.
DR EnsemblMetazoa; XM_013548981.2; XP_013404435.1; LOC106169511.
DR GeneID; 106169511; -.
DR KEGG; lak:106169511; -.
DR InParanoid; A0A1S3J1Y4; -.
DR OrthoDB; 5352941at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0009966; P:regulation of signal transduction; IEA:UniProt.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 3.30.70.1390; ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2; 1.
DR InterPro; IPR032171; COR.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020859; ROC_dom.
DR PANTHER; PTHR48051; -; 1.
DR PANTHER; PTHR48051:SF1; ZGC:77287; 1.
DR Pfam; PF16095; COR; 1.
DR Pfam; PF13855; LRR_8; 2.
DR Pfam; PF08477; Roc; 1.
DR SMART; SM00369; LRR_TYP; 7.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51450; LRR; 3.
DR PROSITE; PS51424; ROC; 1.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000085678};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 277..505
FT /note="Roc"
FT /evidence="ECO:0000259|PROSITE:PS51424"
SQ SEQUENCE 904 AA; 103366 MW; F8A6D4BB6E198E39 CRC64;
MDQKQVKAGK ESLLILEKLQ DTCPSRTPVS VLEWTLIDYD NADIEVIPES IKWCFNVRKI
YGQRNKLSSL PQSISDLQFL KELWLGNNQF EDFPSSVCDV TLLELLDLSG NQLLKIPRDI
NRLRNLRSLY LSNNKFTDFP TAVCGIRKLE ELQLDNNQLS QIPDSVQQMD NLHILELGNN
DFNAIPDHIC SIPNLEKLFM ENNAITHIPP SIGNLQKLNK LKLDQNKITH LPHALVSAKN
LLDIHLHDNP LVEPPESVCS KGLEAIGRYF HELKDSKAVQ SSRIQLNLLG ETGSGKTSVS
LSLQRDKPTL TAQADRTRVI AQGSCETQPD IAFNINDFGG HDVYKVSHPI FISKNGIVLI
AFNLVTYNLS NPDHYGLYIG DWIDKVQAQT PGMRIALLGT HFDEVSTEAA MTIRQAVLKQ
MKQHMEKKKR WLKTQVSNID EKIEDLQQSP EQEEIIQAYR VKQGRLSKAA NHVVDVCDHV
FMVSSKTMEG YPQLKEYLSN QAQRWAVSLP GTWVQAANAI RIQKYENSNN TLDWVALQEV
ISQHAPRSWQ KRSPTEKRVV ICDILSFLAS RGDIIWFDTS PTLARVIFHK QEILAGLLKA
VLNHDLEHLM VKLLRPLKIS RPRLEDIRED FAVRGIVSKD VMKCLWGQFH LSSVETEVLV
ELLQQLELCY QVEKGTAVTP DTTFHFPWLL TEDRQQELEE KWPRCLPQDL IQVTLEVYFP
YKCPDGMFEK FSVRQHNYLG FYKSHRMDWK DGLYAQVRGC RIQISRSQRE SDWVITVAIR
GRNIEDLWPP LHRAHSDLMS VIQEDWPGVS YDKFLVCPHC VKEGFNRPHL FPGELLDRPP
PISGEDADVP CRNCDDLIDA GLVHPATKAE ICHKGKNIGN RGRLFVTSTV GHFPHGHFLM
YKIL
//
