ID   A0A1S3J441_LINUN        Unreviewed;      1136 AA.
AC   A0A1S3J441;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=ATP-dependent DNA helicase {ECO:0000256|RuleBase:RU363044};
DE            EC=3.6.4.12 {ECO:0000256|RuleBase:RU363044};
GN   Name=LOC106169925 {ECO:0000313|RefSeq:XP_013405048.1};
OS   Lingula unguis.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC   Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX   NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013405048.1};
RN   [1] {ECO:0000313|RefSeq:XP_013405048.1}
RP   IDENTIFICATION.
RC   TISSUE=Gonads {ECO:0000313|RefSeq:XP_013405048.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000256|RuleBase:RU363044};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|RuleBase:RU363044};
CC   -!- SIMILARITY: Belongs to the helicase family.
CC       {ECO:0000256|RuleBase:RU363044}.
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DR   RefSeq; XP_013405048.1; XM_013549594.1.
DR   AlphaFoldDB; A0A1S3J441; -.
DR   STRING; 7574.A0A1S3J441; -.
DR   EnsemblMetazoa; XM_013549594.1; XP_013405048.1; LOC106169925.
DR   GeneID; 106169925; -.
DR   KEGG; lak:106169925; -.
DR   InParanoid; A0A1S3J441; -.
DR   OrthoDB; 929107at2759; -.
DR   Proteomes; UP000085678; Unplaced.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR   CDD; cd18809; SF1_C_RecD; 1.
DR   Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR010285; DNA_helicase_pif1-like.
DR   InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR   InterPro; IPR025476; Helitron_helicase-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR47642; ATP-DEPENDENT DNA HELICASE; 1.
DR   PANTHER; PTHR47642:SF2; PHD-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF14214; Helitron_like_N; 1.
DR   Pfam; PF05970; PIF1; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU363044};
KW   DNA damage {ECO:0000256|RuleBase:RU363044};
KW   DNA recombination {ECO:0000256|RuleBase:RU363044};
KW   DNA repair {ECO:0000256|RuleBase:RU363044};
KW   Helicase {ECO:0000256|RuleBase:RU363044};
KW   Hydrolase {ECO:0000256|RuleBase:RU363044};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU363044};
KW   Reference proteome {ECO:0000313|Proteomes:UP000085678}.
FT   DOMAIN          2..108
FT                   /note="Helitron helicase-like"
FT                   /evidence="ECO:0000259|Pfam:PF14214"
FT   NON_TER         1136
FT                   /evidence="ECO:0000313|RefSeq:XP_013405048.1"
SQ   SEQUENCE   1136 AA;  129145 MW;  74F84104A2EF1569 CRC64;
     MKDLCAMVKQ LGIPTWFCSF SAADRRWKEI VYAILKSQGK VVPDEMDWTE HCKVINSNPV
     IAAAMFDKRS HHLIHDLIKS ASHPIGNVTD FFYRIEFQQR GWPHIHALFW VQDAPILDRS
     EPTDVVSFID KYVTCQLPHE EEPLYEKVSK LQMHSKNHSR SCRKGNQTCR FNFPRQVSTR
     TFICKPIKLD EEQPKQIIRK EAREALEKLA KITSDEKNIS LSSQQCLELA GMTQESLEYS
     MGVLARKTVI VLKREPRECW INQYNPHLLE AWDANIDIQY IVDAYACICY IVSYISKKES
     EEGELLKAAQ KEAREGNTEA VNELKTLGKV YITHREISVM EAIYRCTGMK LKCSSREVRW
     IAADKDATRL SLPLNILKQQ AKEKRLDNIW AKSDLERGQD ILPSAFTSYE TFHNNACFVI
     NDEEIPIYEL VNRNSAPFEK DAEVIDIALQ RSHDDHEDAW ADIAPGAEEQ RIDDKMDQNL
     STIGEDAVEE VHLPDLEAAL PDKIAYRKGN LFSENLKLQI STKQAKNMLR SMNIQQLHIF
     NYMRNWCLEK SQGKNPKPFH IFLTGGAGTG KTHVINTFRY EAENILTSVD SPNENPDDVK
     VLLVAYTGTA AFNIQGQTIH SAFAIRSQKG KNRKKYVPLG EELLTELRVK YRSLQILVID
     EISMVGQNMM MNISQRLNQI KQTNSAQAIF GDISVLAVGD FYQVAPVADK ALYVTDPGQL
     YESEWNNFVK YELSIIMRQK DDQPFANLLN AIRTKKKEEQ LKPHDKAMLL ERVNDQLTAD
     STKLYIFPRN KEVDEHNKHL LETLCSDIIS IEAADIIHSR SGQTKRKKVP FAKDSLALKP
     LLEIAINARV MLTTNLNVSD GLSNGVMGTV VKIEQGTKPL NQPQYIWVHF DNPNIGANTR
     QQTVRPENIP TNSVQLQPHV ELFDHQSVKV ARYQYPLKLA WACTVHKTQG KTVTDAVVSL
     KHVFAPGIGY VALSRATKLS GLQLQSFDQT DEANLYCDIK VDDAMKAMSP LNPDILPLLR
     PLQKTLTIVC HNIQSLPAHF TDLKSNPEMA VADIVGITES WLHSNVPSSK YSIPGFKLIR
     CDRQNDTSRG GVAVYIRNTL KVMEVKNNSV TEPGFESLSM TINGYYISFM YRSPSI
//