ID A0A1S3J7J5_LINUN Unreviewed; 2116 AA.
AC A0A1S3J7J5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=WD repeat-containing protein 81 isoform X2 {ECO:0000313|RefSeq:XP_013406370.1};
GN Name=LOC106170885 {ECO:0000313|RefSeq:XP_013406370.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013406370.1};
RN [1] {ECO:0000313|RefSeq:XP_013406370.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_013406370.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_013406370.1; XM_013550916.1.
DR EnsemblMetazoa; XM_013550916.1; XP_013406370.1; LOC106170885.
DR GeneID; 106170885; -.
DR OrthoDB; 5491602at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR CDD; cd06071; Beach; 1.
DR Gene3D; 1.10.1540.10; BEACH domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR44662; WD REPEAT-CONTAINING PROTEIN 81; 1.
DR PANTHER; PTHR44662:SF1; WD REPEAT-CONTAINING PROTEIN 81; 1.
DR Pfam; PF02138; Beach; 1.
DR Pfam; PF00400; WD40; 3.
DR SMART; SM01026; Beach; 1.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF81837; BEACH domain; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000085678};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 444..741
FT /note="BEACH"
FT /evidence="ECO:0000259|PROSITE:PS50197"
FT REPEAT 1819..1854
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1868..1898
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 171..190
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 313..360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1215..1293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1681..1703
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 338..354
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1269..1293
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1685..1699
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2116 AA; 237771 MW; 8EEF3D8512EF5922 CRC64;
MEILHMIRDE LNIHPGCIRL VSCHRAVCLV QTEWLKKACN KHKIPTASRY NHSLSEIEYE
RLLAASTTDV PEPWERISVK VIQKRNEKVK CFPESFGLPH LENGLIDSLA YVTDENYRRS
WQNAFERFGS CGRNLESSTA PPAKPFCDFV RDVIQRLHNC SIYPLKSFEN GRREGVPEEE
EEQNDISQLD SPHPNLIPLY CAFESDSAFY LLQPYMTYSL QDCVTLSPAI LGNSYAKPLF
IVYQILHALR HLHNKGLSLG NRKLRDILID SKLWVQCSYP TMKSLTEDVL YECQKDPDEI
AVNAEGKEVT SSNSSTVLTK GCSTIENGER GEGNGAESGA EMDEDVDEEA EDISDGNTGS
QYHVSESVVH VDVKTGSSVG QTNFAPRAPS STSQVIQGAS TQLESVREQV ESSLESSDEH
FPDIIPDNHS ALETDCAMSR AFLHDEPSLE TLPKLTDDWI NGRISNFKYI MALNKLAGRR
MGDPNNHPVL PWVIDFTTPN GEYRDFSMSK YRLNKGDDQL DVMYNVSFSS SVPGRTEGLI
QVPHHISDVL SDITYYVYKA RRTPKDILCT KVRSKWVPRE YPSSMQRMQE WTPDECIPEF
FTDPSIFASI HGDLPDLEIP PWSSSPMDFV TKHMAILEGD YVSSQLHLWI DLTFGYKLSG
AAAVDAKNVC LQLVDEHTNL TNHGVVQLFQ SPHPQRNCGQ KSFSSSLPPN VMRNMSSYNY
LKSLHEIPQN EFVKGTGDPY RIQAALQVFS ETVEKDLPRP GTPPTERRLQ SDPGLVANMM
PWKVPITLPE NYDPLELLNE VERGCGFSTS VLHSWPQRKT VEEIQTVQAQ IQDKVNRDMQ
ILGCLLVEMF LSAKLHAISF ETSFKGRCRI VRGVARQFFH ELPRPIRHVV KWLLQLNRSL
PASAADSNLA FPYRLQSREG LPPPNASILL EPTFQVISFP AYFPELYAFL KELRAADNSL
FSHFNDVHEV SDDGSFSKLM KNKVDIFARN FSQLSPKLDE AGVELLMPYL KELFSDRATM
VNAAWNLFGP VAKLLGPTAM SKHFLQSLTK LYDGENTTPK HFKLYHRTFL LQLLIRLGLE
AFLSSFVTLL IEATSGYKDF IPDVTSDPSM THDDNDLDSA SMETDEDTVI KYDFISSEEG
VASGFLDRQI SEMSEQALQF DENFPEKISL DGVEEEDGAV ACHHNNSTDT DSIGDQKSIT
SARSDLEMED IKGGEVQAAS NPALDVPSDD APDSIAGSLG THSTPLVPAH KWGSKGPMEV
KESEIGARKR ISSQTSISSA DQTPEQKGKQ TVQRKKWSLS CTLDSTMNRS EYNVRDVATE
TVKWLSQKLG PVLTAKHLSH NLLRMLVLCY LEEEQLCFVE FDEIDNDISA CKKMVVGDLN
ASKILESLGY IAVLYGEQTV ALQYFKHMLE LVFTAMKRLT PRSEAGLVSC LTLLKYIIPY
LSDTTLMDYL QDDGMKTTRS ILKDMLYPTI ELLSSTTISF PSGGHVRKLL CYKVVDVIYL
ICLRIGFEQT RQHMSQVMQC FFQVFDLVHE RKHSGNNEPK RSSATAIPNK KESLTDSNEL
FLEIKKDSVN NEYKIGTPVC VADLISPTKS FGSSGSWHRR SHSLTPLEPV VPHSQADEDN
PEQVATKEKI MDELRQTFTP EMAYTAYIPL CQVYGGIHME QYLKNESLIR ELCTRHDEET
SLQNKMDYSG DSSDSGESDG FLNGFLGEQK DKEDIVTGSF GKNVKVVGNK LAVSCEDDHL
VSMAAVKQDR LLPKKKLPDV RRSVDNPKQI DIKKLKCPEM ETATSRHLKG NWLAYWEHEI
GLSEKDTRFN FKQIKLQTFS NHTNSVRSIH VMDNENCFFS ASKDKTVKLW SIQSFGDGSA
RSHPQWTYLQ HRKPVLAVTF LESMRLAASS DSSVHIWDPF VGMPIRQFDS SKNNPVAAFC
CMSPPHNTIL CGTNEGSLRF LDVRAGKFMQ EYKCVTGPAG VLRCVTVSPS GNWVAVGFSA
GVLSLLDTRT GLLLGTWKGH EGDIMKLKAF NDRKFVTSGV DNMVHLWRTD VDQRYMCSMK
GHSEPVHGIS FYRNEMISIT AGNKIGVHTS LDSHAMFSST KLRSDTFKGS LTSMAVLPLN
RMLLLGADNG SIKLLC
//
