ID   A0A1S3J974_LINUN        Unreviewed;       660 AA.
AC   A0A1S3J974;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=THO complex subunit 1 {ECO:0000313|RefSeq:XP_013406771.1};
GN   Name=LOC106171155 {ECO:0000313|RefSeq:XP_013406771.1};
OS   Lingula unguis.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC   Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX   NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013406771.1};
RN   [1] {ECO:0000313|RefSeq:XP_013406771.1}
RP   IDENTIFICATION.
RC   TISSUE=Gonads {ECO:0000313|RefSeq:XP_013406771.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_013406771.1; XM_013551317.1.
DR   AlphaFoldDB; A0A1S3J974; -.
DR   STRING; 7574.A0A1S3J974; -.
DR   EnsemblMetazoa; g2706.t1; g2706.t1; g2706.
DR   EnsemblMetazoa; XM_013551317.1; XP_013406771.1; LOC106171155.
DR   GeneID; 106171155; -.
DR   KEGG; lak:106171155; -.
DR   InParanoid; A0A1S3J974; -.
DR   OMA; LWNSWKN; -.
DR   OrthoDB; 5490969at2759; -.
DR   Proteomes; UP000085678; Unplaced.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd01670; Death; 1.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR000488; Death_domain.
DR   InterPro; IPR021861; THO_THOC1.
DR   PANTHER; PTHR13265:SF0; HPR1; 1.
DR   PANTHER; PTHR13265; THO COMPLEX SUBUNIT 1; 1.
DR   Pfam; PF00531; Death; 1.
DR   Pfam; PF11957; efThoc1; 1.
DR   SMART; SM00005; DEATH; 1.
DR   SUPFAM; SSF47986; DEATH domain; 1.
DR   PROSITE; PS50017; DEATH_DOMAIN; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000085678}.
FT   DOMAIN          578..660
FT                   /note="Death"
FT                   /evidence="ECO:0000259|PROSITE:PS50017"
FT   REGION          536..571
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   660 AA;  75972 MW;  A8148D4469490D33 CRC64;
     MAASTASGSD FEKQRQTCLK FIEKHHNSTD LNGLRDEYQT LPGSESERKL ALDQAFRDAV
     HKQVQSGGDI NILTSLINLA VEAVRQELGS HSTPFLLLQD TFDGLELEKC SSLFKFVEDG
     VATWKSDIFY SAGKNYLLRM CNDLLRRLSK SLDTVFCGRI QLFLARLFPL EEKSGVNLTS
     QFNLDNVTTF SSSAEDFVRK SSETDGEKDD SMEIEEGEME DTLSSSIPID YNLYRRFWSL
     QDNFRNPQQC YEKIAWKQFV VNADEVLKVF TSNKLDDIKS SRKNLEQPKQ SDTHEYFAKY
     LTNEKLLDLQ MSDGNFRRYV LVQFLILFQY LNSTVKFKSA NQVLSEEQSN WVRESTDKVL
     QLLRETPPDG EQFAKYFEHL LAREENWNAW KNEGCPSYVR EATENTAKQK SLRVRKRSLG
     EDIKATGGKV VKMGNDELTR LWNIYPSNME ACKSDKRIFL PSLEDFFEEA ILQADPEQQI
     EEQYKLVSQS NFCWRSLRLL ARRSPHFFAQ TNQQPGALKI SKFVESMVMR IAKEMPSTLQ
     EEPKTELEEE EDIREEHQEE ELDKAEETGK EEAVEVVTAD QVATVAEELS QEWKRLAVEL
     NFPEDDIAYI ESDNEDTVSQ ALKMLTLWME NEAERATPGT LKIALKEVGL IDIANKVFPS
//