ID   A0A1S3JJ91_LINUN        Unreviewed;      1358 AA.
AC   A0A1S3JJ91;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Pleckstrin homology-like domain family B member 2 isoform X10 {ECO:0000313|RefSeq:XP_013410480.1};
GN   Name=LOC106173715 {ECO:0000313|RefSeq:XP_013410480.1};
OS   Lingula unguis.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC   Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX   NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013410480.1};
RN   [1] {ECO:0000313|RefSeq:XP_013410480.1}
RP   IDENTIFICATION.
RC   TISSUE=Gonads {ECO:0000313|RefSeq:XP_013410480.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_013410480.1; XM_013555026.2.
DR   EnsemblMetazoa; XM_013555026.2; XP_013410480.1; LOC106173715.
DR   GeneID; 106173715; -.
DR   OrthoDB; 5477608at2759; -.
DR   Proteomes; UP000085678; Unplaced.
DR   CDD; cd22713; FHA_PHLB1; 1.
DR   Gene3D; 2.60.200.20; -; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR000253; FHA_dom.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR008984; SMAD_FHA_dom_sf.
DR   PANTHER; PTHR12156:SF5; KINESIN-LIKE PROTEIN UNC-104; 1.
DR   PANTHER; PTHR12156; PLECKSTRIN HOMOLOGY-LIKE DOMAIN, FAMILY B, MEMBER 3; 1.
DR   Pfam; PF00498; FHA; 1.
DR   Pfam; PF00169; PH; 1.
DR   SMART; SM00233; PH; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000085678}.
FT   DOMAIN          1249..1351
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   REGION          198..295
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          384..421
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          518..543
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          560..671
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          691..761
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          997..1027
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1100..1136
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          766..992
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        384..407
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        560..611
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        636..652
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        725..753
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1005..1025
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1113..1131
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1358 AA;  154323 MW;  C289608FB95971C4 CRC64;
     MAIDPARAQY NSLERRRRML QIATPVLAEL EEECKDQIEV TEIGKSYKVQ TDKPHLVSLG
     SGRLSTAVTL LPLPEGVTSI GTAENNDIVI QGTGCEADHC TVENCNGLVT LYPGADLCSV
     DGLKVNRPTI LSQGCMLCLG RSNYFRFNHP QEAIRMKNAL PNPRISMAPI GFLPGLESNP
     DYYKNLAENN RMPTLDQIQH SVQSQSRTEQ SYGQGLHNIQ KSSGNSYGPG GQNNLSYSSS
     PGGRNNLSYS PAHNSGTYTT FHEGYSSSPG GWKDSSLLEG RNDLNQTPQA AEGNSDETIF
     NHRDNLEKEN FVSKISRFEA LTHSMANKAP PHVKGIQKYT YLNTSGSPPN IYQQHMGEKV
     FTKQTSTTRV SLDNNTADRI GSMASTASSS SFTSVSSASS SQSNDTVKSE EHVMRSRGTV
     GAKQNSVASI VSTDTSIWGS TSTMPDNYLQ DMARLSENRD SVFSDISDIS ELTESQLELS
     LKHKQMKEER VKEQAQEKFE RQRLEDILSM CAEYERQLEK EKGGSKDGPP YSTPTPPSSL
     YFEQLSDGSA NSLERKRIKT NGSLLSSPTS SVQKLSSPTT GQGQFSSSPG QGQAFDFKVM
     SRSTSSTSED DVDSGTIKRK PKVPTSLTNQ EKYDNVDYDY VAERDPEEDP RTPTAASPEA
     GQVKDSAVEE EEVDIFECVK QNVTQRLITE AETSREEEED GDEVEHAHVE SLSVQLKDVE
     SAKESVTEQA SPASDQSIGV KSSSGVETSS DHSLATSEEN DRRIQLEKLK KMRVDAVNTI
     TDLKQKIVDI EGQQNEAIRE LEMERALLEG EHQTEMVQLQ REQDRINSLK QKQLELIERA
     TAEKERKRKV RFTTQLEQEK MDAERHKLRE LEHKHYEVEQ QLECCSREEE PLLLDELQKY
     QDAIENQRKI FDDLEFQQLE VETRYEEERE VVQQQLLQEQ NQLLGKYKAR EERLHQIDKQ
     QRDMLKQVKV DIEGLETERQ KLVEEFRKEK ATLSTIDRKI RELSRNNSTS PPGDTSSASA
     KSSDTEYEMK VNEEFFRRLQ EEELKTPTNE MTMELSDKLA KTYLSDDKGA KFIEDQKKYL
     EDLKRRATQE GHVQWAEMHQ REAKARSYGS VESEEGSVDS GSTPSDKATS LSSGEDHLEK
     LTEMERTLSQ AQTEKIKQLE NQVQFREAEM RQLLAERQRR EDLERRLQDE IAKREELVEQ
     QVKMREKQRQ QSRPLTRYLP VKSKDFNLRL HIESAGHNLE LCPHVVLDAV SCKGYLHKMG
     NRFKTWHKRW FVFDRVRRSF LYYTDKSEAK PRGGMYFQAI EEVYVDHLRT VKSPNTKLTF
     CVKTYDRTYY LVSPSPEAMR IWVDVIFTGA EGYTEFQS
//