ID A0A1S3JN26_LINUN Unreviewed; 1299 AA.
AC A0A1S3JN26;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Interference hedgehog isoform X1 {ECO:0000313|RefSeq:XP_013411337.1, ECO:0000313|RefSeq:XP_013411338.1};
GN Name=LOC106174354 {ECO:0000313|RefSeq:XP_013411337.1,
GN ECO:0000313|RefSeq:XP_013411338.1, ECO:0000313|RefSeq:XP_013411339.1,
GN ECO:0000313|RefSeq:XP_013411340.1, ECO:0000313|RefSeq:XP_013411341.1,
GN ECO:0000313|RefSeq:XP_013411343.1, ECO:0000313|RefSeq:XP_013411344.1,
GN ECO:0000313|RefSeq:XP_013411346.1, ECO:0000313|RefSeq:XP_013411347.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013411344.1};
RN [1] {ECO:0000313|RefSeq:XP_013411337.1, ECO:0000313|RefSeq:XP_013411338.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_013411337.1,
RC ECO:0000313|RefSeq:XP_013411338.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_013411337.1; XM_013555883.1.
DR RefSeq; XP_013411338.1; XM_013555884.1.
DR RefSeq; XP_013411339.1; XM_013555885.1.
DR RefSeq; XP_013411340.1; XM_013555886.2.
DR RefSeq; XP_013411341.1; XM_013555887.2.
DR RefSeq; XP_013411342.1; XM_013555888.1.
DR RefSeq; XP_013411343.1; XM_013555889.2.
DR RefSeq; XP_013411344.1; XM_013555890.1.
DR RefSeq; XP_013411346.1; XM_013555892.2.
DR RefSeq; XP_013411347.1; XM_013555893.1.
DR STRING; 7574.A0A1S3JN26; -.
DR EnsemblMetazoa; XM_013555883.1; XP_013411337.1; LOC106174354.
DR EnsemblMetazoa; XM_013555884.1; XP_013411338.1; LOC106174354.
DR EnsemblMetazoa; XM_013555885.1; XP_013411339.1; LOC106174354.
DR EnsemblMetazoa; XM_013555886.2; XP_013411340.1; LOC106174354.
DR EnsemblMetazoa; XM_013555887.2; XP_013411341.1; LOC106174354.
DR EnsemblMetazoa; XM_013555889.2; XP_013411343.1; LOC106174354.
DR EnsemblMetazoa; XM_013555890.1; XP_013411344.1; LOC106174354.
DR EnsemblMetazoa; XM_013555892.2; XP_013411346.1; LOC106174354.
DR EnsemblMetazoa; XM_013555893.1; XP_013411347.1; LOC106174354.
DR GeneID; 106174354; -.
DR KEGG; lak:106174354; -.
DR OrthoDB; 3138076at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 3.
DR Gene3D; 2.60.40.10; Immunoglobulins; 8.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR44170:SF30; FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF00041; fn3; 3.
DR Pfam; PF07679; I-set; 2.
DR Pfam; PF13927; Ig_3; 3.
DR SMART; SM00060; FN3; 3.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 5.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50853; FN3; 3.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000085678};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..1299
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014545942"
FT TRANSMEM 990..1015
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 31..102
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 135..220
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 232..311
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 322..407
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 439..535
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 593..677
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 732..833
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 840..936
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 412..440
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 532..599
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 686..742
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1096..1182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1194..1299
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 552..592
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 697..721
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1115..1171
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1205..1220
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1237..1286
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1299 AA; 143488 MW; 8B2B7943CEC939E0 CRC64;
MELPMCHMRW LLSCYLLLPW ILESVTPEVL PSFVVEPESQ VVKKNAEVVL SCQVAPPTAE
IRWKYNGHYI EPSTDDRMQI RADNSLHISA FKAKRHAGTY MCGGSTPEGT ILSRPAKLHR
ARLGHFTNGG QSRGIEVVVV NATEGNTAVI PCEIPKGEPT PVAIFEINST TIDKSTERYK
LHPSGNLHIG AVRQSDQGLY SCIVKNTVSG KKKDSTKQIQ LKISTPLANV GPRFILPPPK
NTEVILGSTL TLECAVGGSP VPRVSWDKYG GQLPEGRFRQ EFGTLLIENV QIQDIGTYIC
SGDNEVDSAV TAIAMVDVLV PPEITNAPSN KVVTVGDTVT FHCETYGTAR IKTQWVHDGE
PVPDTDQSIQ VQDTSITVSN IQMRHSGIWQ CLVSNKYGAT YAYAMLTVIP SNSTTNQPPG
GSEGEEEGTS SSSQNGVLPP TMPEVLQIEE NMVLLKWSVP LNLQTPVKYF KVQYKEEGVW
KTHANTSACS TCMFSLQGLR TGIPYKFRIA AVYSNGEELV SPNTERFKLL QAPKIPDDDG
NVQDIQPDDG PVSPSAVTTS SSIASTNSGS NNGDSSNSNM DGVSSNNDHP NKPIFTLRPA
NTERKVGEMA VLYCIAEGAD ELRWRQEGRP LRPDPRHIIE DGSLKIFNVQ PWESGAYMCV
AVNRFGFSIA TAHLLVTGNA TIREPASVDR SRDNPRYKQS TLCTTQRHPP TTPSSRGENQ
GHRGSGGRKK VPPSRPAVTQ LSDSSVMLEW SVPPNDGLRV TLFRVQYKRH KRRGNKGRWR
TIDEDIPDNQ FRYELRGLSL GHSYKFRIAA VYSNNDNAVG PTSPPFTLVA GPTSHPSAPE
VGPVIVQVKP SAYAMEIEWQ YAHHIGEGPI DGFWIHYKPY NAPDSQSQKV TVPPVETKYR
IIGLTPDTQY SFKMQCFNLA GASDFSNKVA MKTLAADGSQ PMFTPFPTGI LTPVTRPPGN
GLGPHLDDGQ DDVKDDNAVP ANSTQKSNEL LYMVLGVVLG VMMLLLVIFM VMCAWKQRQQ
RRMMAAALDA NARYKFQDPS QRIHNDSMRA KHGNGFLLNG LNGKTPNGHL SNGHAGNGHI
PNGNGKMNIN VNPMTQLEPL HNSDNEEEAI SENESNPDDP YTTQSTLPHR PLQTFGYPND
SNYNTLERNP YPSYHDNNTE HMNSNIPQSR DHIPSDPPDY SAIRLHNNYV HRSHDHISGV
RGQTPRSHDL GTTSEHSYPS QGSAKHKRRR KRPSREQQSP YTGTQMKDQA TNTDLSSNEG
TLDSSFTYPS QEGHHQDRTQ PTPIPHSDYR HSPDMYSVE
//
