ID A0A1S3JSL1_LINUN Unreviewed; 1229 AA.
AC A0A1S3JSL1;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Protocadherin-1 {ECO:0000313|RefSeq:XP_013413109.1, ECO:0000313|RefSeq:XP_013413110.1};
GN Name=LOC106175590 {ECO:0000313|RefSeq:XP_013413109.1,
GN ECO:0000313|RefSeq:XP_013413110.1, ECO:0000313|RefSeq:XP_013413111.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013413111.1};
RN [1] {ECO:0000313|RefSeq:XP_013413109.1, ECO:0000313|RefSeq:XP_013413110.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_013413109.1,
RC ECO:0000313|RefSeq:XP_013413110.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_013413109.1; XM_013557655.2.
DR RefSeq; XP_013413110.1; XM_013557656.2.
DR RefSeq; XP_013413111.1; XM_013557657.2.
DR STRING; 7574.A0A1S3JSL1; -.
DR EnsemblMetazoa; g3567.t1; g3567.t1; g3567.
DR EnsemblMetazoa; XM_013557655.2; XP_013413109.1; LOC106175590.
DR EnsemblMetazoa; XM_013557656.2; XP_013413110.1; LOC106175590.
DR EnsemblMetazoa; XM_013557657.2; XP_013413111.1; LOC106175590.
DR GeneID; 106175590; -.
DR KEGG; lak:106175590; -.
DR OMA; CYVPDRI; -.
DR OrthoDB; 2996291at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 7.
DR Gene3D; 2.60.40.60; Cadherins; 7.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR PANTHER; PTHR24028:SF146; CADHERIN FAMILY; 1.
DR PANTHER; PTHR24028; CADHERIN-87A; 1.
DR Pfam; PF00028; Cadherin; 6.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 7.
DR SUPFAM; SSF49313; Cadherin-like; 7.
DR PROSITE; PS00232; CADHERIN_1; 2.
DR PROSITE; PS50268; CADHERIN_2; 7.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000085678};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..1229
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014545957"
FT TRANSMEM 821..845
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 52..148
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 149..258
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 260..366
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 387..482
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 483..586
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 589..694
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 709..806
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT REGION 866..940
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1009..1057
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1149..1185
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 866..905
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 917..940
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1010..1034
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1035..1049
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1156..1171
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1229 AA; 134528 MW; 88789A0EBD7F0C52 CRC64;
MAFVNMPSNM RFFTCVVLAS VFIIQSAAQT GPGIHSKVRE GGSAGLYVGN IATDANYTRR
FSDPVLQQLR YNFLTQGYPG TRYFRLDNQT GVIRTSETIN REEVCADDLS VRCLVDLAVS
VKNVPVQYVE IIKVQVEIED TNDNSPSFPS DSLDFEVSES VSVNHTLFTN GATDPDFGTN
SVQHYELLPQ NSAFGLVQQT TVDGATELGL RVLQPLDRET TDSYSLTIIA RDGGVPVRSG
TVRISIQVRD INDNTPVFDQ VDGYEKSITE TAGPNFSVLT VHASDPDEGT NGEIAYSFSS
GTSAKIRALF DINSNGLITL KGNVVYDDSP YQFTVYATDQ GTPEARSSRT TVTVNVVDVN
DNEPLININI ISSSPEPQYA GHAVMWESEG AGKYVAHMAV SDADSGPNGQ TKCELATQDF
RLVKYPNDDN MYKILLDTDL NREERSEYNV TVNCWDEGSP PLRSSASFLA IVLDENDNDP
VFSHQIYGAQ IEENNAVGAL LVTVNATDAD IGNNALINFQ LSSGAGGLVT LDPSTGEIRA
KKQFDRETTP SFEFHVIAAD SGSSANTATA TVSVTVLDQN DESPVFKGSN LPYEFRIKEN
QTRYQYVGEV FAEDRDEGSS GQVWYGLDPN SEGAELFTIE PNTGRITTNQ SLDRERKGSY
RLVVIARDRG TTVQSTAIEA EVILLDINDN PPNIIYPYGD NNTVSLSYGT PVGITAATIV
AEDIDSGVNA ELVYSLDKPD SHNIFRIDPA TGDIIISREM RLDDITKSRS RPYRLVVAVT
DQGTPSNQVL VDFYIHVTND PYVPLVGPNK SQMGEGLGQN LIIVIVLATV SAILAIILVI
AIIMIKRQNK DNHAYNCRTE AQRALNGSKR SFGSNNSNNN DFKPEESGQC VMREQQLTPR
SESSLLGRPD GQEMRQSPGG GTLSGTEIST FKSHPSFTSS IDQKTLENPQ ATSSLLQVTP
ELIFEYARDK PQELNALALH KVPQKGNRQQ QPWVLSQKEK EAQELLDILK KPANQSTSNT
DIDSECSGEV SNTDSGRGHS EEETQGMEGQ QVRAKKYAPA RDPYQPKSIL HPNARFHKNR
TSTDSGVFMN NNQGNKKNIG RVSQVPPCAI QVVSENNVCN QNIPRVQGSG RQEADDHGKM
HTKVHFSSDI DYHSNSGDSN SEHRDSDGFS DSESTGSEYS SGDVEEELNV TAEKINAQNM
STVSAASSCV DPNQLCLDID QMFFQDMVV
//
