ID A0A1S3JUD3_LINUN Unreviewed; 2159 AA.
AC A0A1S3JUD3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Down syndrome cell adhesion molecule homolog {ECO:0000313|RefSeq:XP_013413706.1};
GN Name=LOC106176041 {ECO:0000313|RefSeq:XP_013413706.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013413706.1};
RN [1] {ECO:0000313|RefSeq:XP_013413706.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_013413706.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_013413706.1; XM_013558252.1.
DR STRING; 7574.A0A1S3JUD3; -.
DR EnsemblMetazoa; XM_013558252.1; XP_013413706.1; LOC106176041.
DR GeneID; 106176041; -.
DR KEGG; lak:106176041; -.
DR InParanoid; A0A1S3JUD3; -.
DR OrthoDB; 4503820at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR CDD; cd00063; FN3; 6.
DR CDD; cd00096; Ig; 2.
DR CDD; cd20956; IgI_4_Dscam; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 16.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR013151; Immunoglobulin.
DR PANTHER; PTHR44170:SF39; FI24025P1; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF00041; fn3; 6.
DR Pfam; PF07679; I-set; 5.
DR Pfam; PF00047; ig; 1.
DR Pfam; PF13927; Ig_3; 2.
DR PRINTS; PR00014; FNTYPEIII.
DR SMART; SM00060; FN3; 6.
DR SMART; SM00409; IG; 9.
DR SMART; SM00408; IGc2; 9.
DR SMART; SM00406; IGv; 4.
DR SUPFAM; SSF49265; Fibronectin type III; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 10.
DR PROSITE; PS50853; FN3; 6.
DR PROSITE; PS50835; IG_LIKE; 9.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000085678};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 12..108
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 219..306
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 308..394
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 400..493
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 498..582
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 589..678
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 683..783
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 787..882
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 889..984
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 989..1087
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1092..1188
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1192..1287
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1284..1374
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1386..1479
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1484..1580
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 1845..1884
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1907..2063
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1860..1884
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1911..1948
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1995..2012
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2023..2038
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|RefSeq:XP_013413706.1"
SQ SEQUENCE 2159 AA; 239419 MW; 7D7B8959470B2E41 CRC64;
LSNVTNSGPR GPVFIYEPTH SQVAFANTKG TLLDCSAFGR PAPVLEWAKE DGSFVDNIPG
VIEILHNNSL YFPPFQDGAF RADVHIASYR CMASNLVGTI ISRKVKIKAV LIEQYKSYNV
RVNDVWAMRG TTAVFRCEIN PYIVKDYVNI TGWWKSNTVI KPDDRYSILP SGELHIRNFR
DEDTQSTYRC ITNNVLTGDQ KASLPASLNV IAATINSPPH IQDTVSQIKL QEGHTVELPC
TATGYPLPRY SWTKDGTAVV TDQSKVFQRG GNLVIRNVVT SDSGTYICTA SNTLGSKTAA
TQLTISAPLS VSVTPTRQTI DGGDPASLNC SIHGYPVSSV TWFKDGRLLT ADDHVSFEND
RVLRLASVQR MDKGMYQCVA SNEEDNAQGS AQLDLGAAKP LFHGVFQEQY MQQHTSISLK
CIASGNPIPN VTWTLDAGEI PKNGRFRMGY YVTPQGDVIS HVNITDLRVE DGGLYRCFAE
NKVGSLAHQN RLNIYGVPYI RPMKNVSAVA NDKLVIPCYA SGFPLQSIEW SKGGHTLPIN
HRQAVSTAGV LTVENVQKSY DEGAYVCTAS NNKGQIASRS VHVQVMEPPR IDRFNFPKRK
EGDRVSVSCM VSSGDTPITL SWLKDGQAIP LDLGITVQRL GPYMSTLMIG DVTPQHNGNY
TCIAQNSAAM VNYTAELHVD VPPRWVVEPS NSFVVLSQTV LLHCQSTGTP EPTVMWKKAK
GENPGNYQVM DFSETAPNGR PHRHLFPNGT LVINQAREED HGYYLCHASN GIGTGLSKVV
FLNVHIPARF DENKRNHSVL KGASINISCD AIGDMPMSLG WSFNGEQLNW QNNQRLALIL
HNTDRGRTTK LTINPAVRED SGFYVCIAKN AFGDDTLLIE LTVLEKPEAP VDVEVGSKWS
RSASISWRAP FNGNSLLLNY VIQYKNFTDV WSPSTKNLTT LPNVTMATLH GLHPAYNYSV
RMLAVNKLGE GLPSDVVNFT TREEAPSGPP TDIQLKATGS QSLEVTWQPP LPEHQNGVIQ
GYYVGYKIYN SSTPYIYITR QNSQGFTRHY SITNLEKFTK YALHIQAFNS EGAGPKSPDS
VVMTLEDVPS RPPQSVQATP LSSVSIRVLW APPPFYTLNG VLLGFKVLYK PVTPDEDESD
AQVITTKNIN ADIHGLEKFT NYSLQVLAYT RMGEGVRSAP IYVRTEQDEP GQPADVKALA
MNESSILITW KKPLRPNGII QKYIIYFKHN DAMGKEILDR VEVPPSQLSY SVTGLVQNRM
YTFQVSAATI VGEGERTREV SQTPVERVAA RVASFSARVL TPWKENVMLP CLTVGDPVPS
IQWRKRGVSL TPDNSHVKIL ENGTLEIVDV QGVDAANYTC QAVNQYGADE ITISLIVQVN
RDIRTPPRAP TISVAVTTEK SVQVNWRSGS NGGSTITGFI LMYKADHEDW TEVTTRPQNR
TYTAQNLKCG TQYRFKMKAR NSIGLGDLSN IITTKTNGSA PIMPPQSMLL EHINSTFITL
NLNSWQTDKC PITSFTVKYQ VWGDSNWATI PVTRTDLEES HLVEDLHPAT WYIMKVIANS
DAGSTESVLK FATLTYTGEK LPDSLPMDFS LSSTITPIMI THKYEPEFYQ KIHVMVPLSL
ALVLVITISL GTALYCKRRH EAMRWKEAKS NLRRDITAET SLMTDLDKRF DKDSDSSNSL
GYTPEPVHLR NVNLLIMDQS NEELPGPNTD WTNQENAQNT QQEMAGSVDS DGFINPYATF
CYPKPGGPTP PLQPIRTPLL QTFTKHKHTP QHGSQDLVAL EKTEAQRKFA EKFPFALPPP
PPPISTATNV LPEVNLLSHP KYRQATGVGL SPRKFASADA IHALFTGRNG KPGPPPHHHQ
TYSIPSNSRP PSQMSSICEK AGQRNSAISS VTTVSSNHDE LMLAFHNGFP STVTPPDSEN
QKEDSIGTPQ PTDNSSDTTV TEPGIRQFTQ SPPRPDERRQ AACEVPLYEQ NRVRRPSQLD
LSSDTTDYDP LPRRKKSPHR RRRSRGHVLS KKVMRQPRGA PVPIRPSSTS TTNSEEITYA
FDDRGHHRPS SPSEGYLSYP YTESESNPYY VRRRSRRYTP VAKYEVTPDT PGTDENRPLM
MSLAKPALAS PQEEEEVGLI DRIYRTVSNS DLSGSLLVDV PESQDKHYIQ GYTEDFTVV
//
