ID A0A1S3K5R7_LINUN Unreviewed; 907 AA.
AC A0A1S3K5R7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Uncharacterized protein LOC106178968 {ECO:0000313|RefSeq:XP_013417852.1};
GN Name=LOC106178968 {ECO:0000313|RefSeq:XP_013417852.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013417852.1};
RN [1] {ECO:0000313|RefSeq:XP_013417852.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_013417852.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_013417852.1; XM_013562398.1.
DR AlphaFoldDB; A0A1S3K5R7; -.
DR EnsemblMetazoa; XM_013562398.1; XP_013417852.1; LOC106178968.
DR GeneID; 106178968; -.
DR KEGG; lak:106178968; -.
DR InParanoid; A0A1S3K5R7; -.
DR OrthoDB; 2960358at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR CDD; cd15039; 7tmB3_Methuselah-like; 1.
DR Gene3D; 4.10.410.20; -; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR InterPro; IPR036024; Somatomedin_B-like_dom_sf.
DR InterPro; IPR001212; Somatomedin_B_dom.
DR PANTHER; PTHR45902; LATROPHILIN RECEPTOR-LIKE PROTEIN A; 1.
DR PANTHER; PTHR45902:SF1; LATROPHILIN RECEPTOR-LIKE PROTEIN A; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR Pfam; PF01033; Somatomedin_B; 1.
DR SMART; SM00201; SO; 1.
DR SUPFAM; SSF90188; Somatomedin B domain; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
DR PROSITE; PS00524; SMB_1; 1.
DR PROSITE; PS50958; SMB_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000085678};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..907
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010182631"
FT TRANSMEM 597..619
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 631..650
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 670..689
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 709..732
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 752..778
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 799..819
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 825..850
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 72..114
FT /note="SMB"
FT /evidence="ECO:0000259|PROSITE:PS50958"
FT DOMAIN 598..851
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
FT REGION 872..907
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 888..907
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 907 AA; 101209 MW; 49B62D3523A977EA CRC64;
MHTSYLGKMN SLYFLIPLCI SWKLVSSLNS WDLLPPPPPN LGDPVEFYNA TDVCSGTLQK
NIVMTNALKC DRSYSCQRRC GAVASQGEDC SCDEVCKTYG DCCYDYDSIC QSNSRVIRIM
PVIAAVPICV ETSQDEFVLF LGEGCLPHWQ GTDMETKCLS HSTALSHKIP VTDVTNRLHY
TNIFCAKCND VTDYRFWNAS YECSKELEVL KNITDPLEIL KQRSCYFKLH FPPGVTKRRC
QAGRTVNRCP PNNTCTTQIQ EACKKYKNVV DVQGKEYQNE YCAICHGKNV TDMTCPAKIL
FPFIPPIHSV VSGSTDVEIS GSNNRPSLGS FSFSIVMDFT QDAEVHVGVG SGTDDDVTMC
TLDEVTSSCI PSQCRKDYIL RDGACVLGVL VYDVHVNTLW EPKATSDPLS IFITDDFQLK
NYGQILTNLI GEMYGEAVYG FVTFGAARKQ KESFLIHNDF KLQFNKTVEA DEIKEEWINV
TRTERFRSVL GQFVTLVNST ISLSLYHDPY ELGDLMNATN TSDQVLHIAE TDCERVRFDS
YDTTENGNIL LPSMTIINES DVLYDNNGSI LVCRNLLNFT VSSNPQDNLS GDDSKEALGI
LTIVCIAISL VCLLIRIALQ PFVALFQTFP GKLQLSLCLS LVLWKVFFLA RPFASLSGDV
SACIAVAALF HWSLLASFFW MNVIAIDLWK TFRRTSSLQI SAESNKTIFG YVCYATLLPG
GIVALCLVLD YVDIDSQFQP HYSGPACYIS NIYPLVLFLV APIGVILIVN IVLFAMIARS
IHIAISEAGK LKAKRNKHTF LIYVRLFALM GTTWLFGFLS GGLNVLALNF IFVILTTLDG
LLIFIAVVCS RRVWRDLRDR KIITRSSTRT LTLSSSNKLP PTPKSPTPSE SNSLKFSLKQ
DTSLSRL
//
