ID A0A1S3K928_LINUN Unreviewed; 361 AA.
AC A0A1S3K928;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Endophilin-A3 isoform X2 {ECO:0000313|RefSeq:XP_013419130.1};
GN Name=LOC106179882 {ECO:0000313|RefSeq:XP_013419130.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013419130.1};
RN [1] {ECO:0000313|RefSeq:XP_013419130.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_013419130.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the endophilin family.
CC {ECO:0000256|ARBA:ARBA00006697}.
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DR RefSeq; XP_013419130.1; XM_013563676.1.
DR AlphaFoldDB; A0A1S3K928; -.
DR EnsemblMetazoa; XM_013563676.1; XP_013419130.1; LOC106179882.
DR GeneID; 106179882; -.
DR OrthoDB; 25371at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd07592; BAR_Endophilin_A; 1.
DR CDD; cd11803; SH3_Endophilin_A; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR035824; Endophilin_A_SH3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR14167:SF30; ENDOPHILIN-A; 1.
DR PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR Pfam; PF03114; BAR; 1.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR00499; P67PHOX.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00721; BAR; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51021; BAR; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000085678};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 18..256
FT /note="BAR"
FT /evidence="ECO:0000259|PROSITE:PS51021"
FT DOMAIN 301..360
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 165..201
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..182
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 361 AA; 40631 MW; 44F08BD821CE2BD9 CRC64;
MSLAGLRKQF NKANQFMSEK IGGAKGTELD EEFLEMERKI DVTGKLVEDV MARTQEYLQP
NPASRAKLMT VNTISKLRGQ VKQTAYPQPE GILGETMIKH GKDLGDDSSF GQCLVEAGES
FKQLADVKYA LEDSVKQNFL EPLQHLQNKD LKEVNHHRKK LGGRRLDYDC KKRKKDKAPA
SGSAISEDEL QQAEEKFEES KQLAETAMHN LLENDVEQIS QLASFIEAQE DYHRRAADIL
QQLHDTLQSK RNEAASRPRS EFVSKKVTSS FRNSSPAFDN NLDSLDTTGY SLSPAQQSSE
PQQACCTALY DFDPENPGEL GFREGDMITL ISQIDENWYE GSIHGQTGFF PVNYVEVKVP
L
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