ID A0A1S3KFG2_LINUN Unreviewed; 600 AA.
AC A0A1S3KFG2;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Solute carrier family 2, facilitated glucose transporter member 1 isoform X2 {ECO:0000313|RefSeq:XP_013420976.1};
GN Name=LOC106181195 {ECO:0000313|RefSeq:XP_013420976.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013420976.1};
RN [1] {ECO:0000313|RefSeq:XP_013420976.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_013420976.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC transporter (TC 2.A.1.1) family. {ECO:0000256|RuleBase:RU003346}.
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DR RefSeq; XP_013420976.1; XM_013565522.2.
DR AlphaFoldDB; A0A1S3KFG2; -.
DR EnsemblMetazoa; XM_013565522.2; XP_013420976.1; LOC106181195.
DR GeneID; 106181195; -.
DR OrthoDB; 1899001at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR045263; GLUT.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR003663; Sugar/inositol_transpt.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR NCBIfam; TIGR00879; SP; 1.
DR PANTHER; PTHR23503:SF127; FI08437P-RELATED; 1.
DR PANTHER; PTHR23503; SOLUTE CARRIER FAMILY 2; 1.
DR Pfam; PF00083; Sugar_tr; 1.
DR PRINTS; PR00171; SUGRTRNSPORT.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00217; SUGAR_TRANSPORT_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000085678};
KW Sugar transport {ECO:0000313|RefSeq:XP_013420976.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU003346}.
FT TRANSMEM 20..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 74..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..128
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 134..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..186
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 198..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 318..341
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 348..370
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 376..403
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 415..435
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 447..465
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 26..469
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 543..600
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 543..561
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 562..578
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 600 AA; 65946 MW; ABD6CE63EDB0E75E CRC64;
MTAEKVAFTH DPRLKGRVTV PLVVTAFAAV IGGSFPHGYN TGVLNAPQDL IIQFLNDTYL
IRTGNEPGKG MLNFVWSFTV AIYLVGGMFG AFSAGWFADR FGRKKAIIIM YIPTFVAAIL
FGLCDVAESF EMLIIARFIV GFGCGAGSGL VPMYMTEIAP VNIRGAMGVL HQLALTTGIL
VSQIFGLRQI LGNENWPILL AFVGVPCLIS AFILPWFPDS PRYTLIKLKK EKEAQEALQT
FRGADHDVSA DIEEMRREQK QLQKQPPWSL GKLFRSKMHR MPFMLVSALA LAQQLSGINV
VFYYSSSVFK DAGIPDDYVQ YATLGTGIIN VIMTVISVPL MEKSGRRILL LGGMILMLTS
AVIITIALNL KDILPWMAYI CVICMLLFVI GFAIGLGSIP QFIGAELFKQ GPRPAAMSFG
GMLNWLANTL VGISYPSMED AMGPYSFIVF VALLLFFLIL IWKFLPETKN KSFAEIAAHF
GIKEDEMADA EDNKESVEML PMHDRVGTRL AATAPANARQ NGSHSMPTTH IPQVVIEDEA
NATNPTIGNP AINVTDDDFQ QQPLISKEDS HRSPRKPNIP MDPEVGRPRS GQDVDKEVLA
//
