ID A0A1S3KHZ0_LINUN Unreviewed; 835 AA.
AC A0A1S3KHZ0;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 2.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Transient receptor potential-gamma protein isoform X1 {ECO:0000313|RefSeq:XP_013421841.2, ECO:0000313|RefSeq:XP_023933460.1};
GN Name=LOC106181868 {ECO:0000313|RefSeq:XP_013421841.2,
GN ECO:0000313|RefSeq:XP_023933460.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013421841.2};
RN [1] {ECO:0000313|RefSeq:XP_013421841.2, ECO:0000313|RefSeq:XP_023933460.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_013421841.2,
RC ECO:0000313|RefSeq:XP_023933460.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_013421841.2; XM_013566387.2.
DR RefSeq; XP_023933460.1; XM_024077692.1.
DR EnsemblMetazoa; XM_013566387.2; XP_013421841.2; LOC106181868.
DR EnsemblMetazoa; XM_024077692.1; XP_023933460.1; LOC106181868.
DR KEGG; lak:106181868; -.
DR OrthoDB; 5406916at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005262; F:calcium channel activity; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR013555; TRP_dom.
DR InterPro; IPR002153; TRPC_channel.
DR NCBIfam; TIGR00870; trp; 1.
DR PANTHER; PTHR10117; TRANSIENT RECEPTOR POTENTIAL CHANNEL; 1.
DR PANTHER; PTHR10117:SF54; TRANSIENT RECEPTOR POTENTIAL-GAMMA PROTEIN; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF08344; TRP_2; 1.
DR PRINTS; PR01097; TRNSRECEPTRP.
DR SMART; SM00248; ANK; 2.
DR SMART; SM01420; TRP_2; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|RefSeq:XP_013421841.2,
KW ECO:0000313|RefSeq:XP_023933460.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000085678};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 355..375
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 387..408
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 437..457
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 477..496
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 525..546
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 566..591
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 651..672
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 82..109
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 199..261
FT /note="Transient receptor ion channel"
FT /evidence="ECO:0000259|SMART:SM01420"
FT REGION 812..835
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 835 AA; 96688 MW; 648754AE1F34DBFC CRC64;
MDKVYRKYRE QVLAGKIQDE IGIEAFQTDH FGSGVVRKEN DLNNEEKQYL LAVERGDMAN
VRRYLEDAPV YYSININCTD PLGRSALLVA IENENLEMIE LLLSFGVEMR DALLHAINEE
NVEAVELLLQ YQASRKKDLT LMGHSGDRDM EGYLGGTPSD SFTPDITPII LAAHRDNYEI
IKILLDRGDR IPKPHDVQCS CRECVANSSD DILRHSRSRI NAYRALASPS LIALSSKDPV
LTAFELSWEL KRLSRIENEF KIEYEGLSVQ CQDFAVDLLD QTRGSHELEI VLNHDSSGAV
PHDSSPDRMK LSRLKLAIKY KQKKFVAHSN CQQLLASLWY EGLPGFRRRH IAFKVIMTSV
IGMLFPLWSL IYIMVPKSSL GKLLRKPFVK FICHSSSYFT FLFLLILASQ HIESIDSITL
WGESKASSSL QLGEIRGAPP TIIEWMILLW VIGLIWAEIK QLWDEGAQEY IQDMWNILDF
ATNTLYIATI TLRIVAYMNV ERDVSGGVPT RYVPRKDWNA FDPNLIAEGT FAAANIFSTL
KLIYIFTVNP HLGPLQISLG RMVMDIMKFM FVYFLALFSF ACGINQLYWY YAAARRQECQ
VSENECKKNH EALSNLFEIM QTLYWGNFGL IDLEHFTLKE DHTITQLLLK LMFGTYSWIA
IVVLLNMLIA MMSNSFQIIS SMQDTEWKFA RSKMWMSYFE EGGTLPAPFN IIPTPKTVWN
ILVWLKNVFC RCSKRQKRNR WQSIRKLVKK IHDREQKYQA VVRDLIKRYI MSKQRFKEDE
GVTEDDINEI KTDVSSFRYE LLEILRNNGM KIPEYTQNKP SSSKKKQRKK RYRTR
//
