ID A0A1S3KKH1_SALSA Unreviewed; 707 AA.
AC A0A1S3KKH1;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=G-protein-signaling modulator 2 isoform X2 {ECO:0000313|RefSeq:XP_013978829.1};
GN Name=gpsm2 {ECO:0000313|RefSeq:XP_013978829.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_013978829.1};
RN [1] {ECO:0000313|RefSeq:XP_013978829.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_013978829.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the GPSM family.
CC {ECO:0000256|ARBA:ARBA00006600}.
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DR RefSeq; XP_013978829.1; XM_014123354.1.
DR AlphaFoldDB; A0A1S3KKH1; -.
DR GeneID; 106560444; -.
DR OrthoDB; 4190321at2759; -.
DR Proteomes; UP000087266; Chromosome ssa10.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030695; F:GTPase regulator activity; IEA:InterPro.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR003109; GoLoco_motif.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45954:SF3; G-PROTEIN-SIGNALING MODULATOR 2; 1.
DR PANTHER; PTHR45954; LD33695P; 1.
DR Pfam; PF02188; GoLoco; 3.
DR Pfam; PF13374; TPR_10; 1.
DR Pfam; PF13424; TPR_12; 1.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00390; GoLoco; 4.
DR SMART; SM00028; TPR; 7.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS50877; GOLOCO; 3.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS50005; TPR; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 84..117
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 263..296
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 401..433
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 484..512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 593..620
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 655..675
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 687..707
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 401..419
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 594..615
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 707 AA; 78737 MW; 37037BCAA090917B CRC64;
MLWPKLTQSH TFLAVPSSVS CCFIYGYGGY FIFMMVFIHT RMETSCLELA LEGERQCKVG
NYRAGVSFFE SAIQVGTEDL QILSAIYSQL GNAYFHLQEY SKALEYHRHD LNLTRTIGDE
LGEAKASGNL GNTLKVLGRF DEAVVCCQRH YDITRGMYDK VGQARALYNF GNVYHAKGKS
ICWTGVEPGE IPEEAKVALN KATEYYEFNL SIVKDLGDRA AQGRTYGNLG NTHYLLGNFQ
RAVVAHGQRL LIAKEFGDRA AERRAYYNLG NAYIFLDQFE VAAEHYKKTL QLAMVLKDKA
VEAQACYSLG NTYTLQQDYQ RAIDYHLKHL IIAQELKDRV GEGRACWSLG NAHTALGNHQ
KAIHFAEKHL EISKETGDKN GEATARMNMA DLKLVLGLGQ NPSSSLNTNN SSVLTENHRK
QDTLPGVKSE GRSNSMENLE HIGLGPEKTT VENWDEDVFG PSNPKSSMAK ASSKLFFINR
FRGKKHKKHS SPTRDGVLQD TSNKPTAREV DTHKSGVKIG CSDTLGDDGF FDLLSRFQGS
RMDDQRCSLL DGESRLSDPF SPCTTPPVAM RKSTSACEAN LEPGHFLDLR ASSQGSRLDE
QRASMGSSLP GLRLSTSDQP IRPHPMLSRL MTSADQPQAD DVFFDMLVKC QGSRLNDQRC
EEPPPSTRGP TVPAEDFFSL ILRSQANRMD EQRVPPLSSD LNQPISD
//
