ID   A0A1S3KLS0_SALSA        Unreviewed;       940 AA.
AC   A0A1S3KLS0;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Breast cancer anti-estrogen resistance protein 1-like isoform X1 {ECO:0000313|RefSeq:XP_013979671.1};
GN   Name=LOC106560839 {ECO:0000313|RefSeq:XP_013979671.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_013979671.1};
RN   [1] {ECO:0000313|RefSeq:XP_013979671.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_013979671.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell junction, focal adhesion
CC       {ECO:0000256|ARBA:ARBA00004246}.
CC   -!- SIMILARITY: Belongs to the CAS family. {ECO:0000256|ARBA:ARBA00007848}.
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DR   RefSeq; XP_013979671.1; XM_014124196.1.
DR   AlphaFoldDB; A0A1S3KLS0; -.
DR   GeneID; 106560839; -.
DR   KEGG; sasa:106560839; -.
DR   OrthoDB; 2902504at2759; -.
DR   Proteomes; UP000087266; Chromosome ssa10.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   CDD; cd11552; Serine_rich_BCAR1; 1.
DR   CDD; cd12001; SH3_BCAR1; 1.
DR   Gene3D; 1.20.120.230; Alpha-catenin/vinculin-like; 1.
DR   Gene3D; 1.20.120.830; Serine-rich domain; 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 1.
DR   InterPro; IPR035745; BCAR1_SH3.
DR   InterPro; IPR021901; CAS_C.
DR   InterPro; IPR037362; CAS_fam.
DR   InterPro; IPR014928; Serine_rich_dom.
DR   InterPro; IPR038319; Serine_rich_sf.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   PANTHER; PTHR10654:SF15; BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 1; 1.
DR   PANTHER; PTHR10654; CAS SCAFFOLDING PROTEIN; 1.
DR   Pfam; PF12026; CAS_C; 1.
DR   Pfam; PF08824; Serine_rich; 1.
DR   Pfam; PF00018; SH3_1; 1.
DR   PRINTS; PR00452; SH3DOMAIN.
DR   PRINTS; PR01887; SPECTRNALPHA.
DR   SMART; SM00326; SH3; 1.
DR   SUPFAM; SSF50044; SH3-domain; 1.
DR   PROSITE; PS50002; SH3; 1.
PE   3: Inferred from homology;
KW   Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW   Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          18..80
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   REGION          86..138
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          266..289
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          699..725
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        88..132
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   940 AA;  103584 MW;  8875CB4AF10F4AA8 CRC64;
     MSVPVFCRMF DCLQRASSEN VLAKALYDNV AESPDELSFR KGDIMTVLER DTQGLDGWWL
     CSLHGRQGIV PGNRLKILVG MYDKAGQQQQ PPPLQASQAG SAQTQSPSQL AFPPQSAYTK
     PSPSSQYTAM HPAFSNPGPV PALPDSIYMM PPNHGKPSPS SLYQIPTGPQ APPKAPMLAQ
     KQYHAPVQDI YQVPPSMGPA PVQDIYQVPP SARGPVPGQD IYQVPPSLNQ TQIPPSIEKR
     SWDSKPLGKV VVPTRVGQVY VYDTGKSEQD EYDVPPRHMP PSQQSQDIYD VPPTRAQYSQ
     QVYDTPPMAV KGPPSGQDIY DTPPSVDKSQ LLSQQTVYDF PPSVSKDVPD TPIREETYDV
     PPHFAKLKSL ESQNQGYLIP GGPEPPIPED VYNIPPPPLT GKHHPDAPLG QEIYDIPASL
     RKGGPHDPQD VYDFPRERPA GEDSIYDIPP QVVRDAGATE ELTVSFKRLS ASSTGSTRSN
     LSTSSLDMVP VRELAVPGQA GPGKLLILDL DQAMERLSRL QQGVEGSVSL LMSFISGNWR
     SPTQMEANLP AIRQAVDRMR VAVRDLLEFA RGAVANSAQA TDRTLQAKLG KQVQKMEEAF
     QGLVKSSQAL DAVAWAPSAL MTPSAGSSGD DLDRLVMCAR GVPDDTKQLA SFLHGNASLL
     FKRTNKQQQL PLPPVPHTAD LMGQMTNNNI SAYQMGDGRA NIQSRPLPSP PKLTAEEETR
     DRPYETTEEG WMEDYDYVHL QGKEEFEKNQ RQLLEKGTRH NKTTLEQQQQ LKQFERLEQE
     VSRPINNDIS GWTPPPHYPT AQRSKLSMGD RQLLLFYSEQ CESNVTTLTN AIDAFYSSIN
     NNQPPKIFVA HSKFVILSAH KLVFIGDTLS RQAKSPEVRA HVAQHSNTLC DKLKDIVVST
     KTAALQYPSP GAARDMTERV RELAGCTQQF RMALGQLVAM
//