ID A0A1S3KR50_SALSA Unreviewed; 326 AA.
AC A0A1S3KR50;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=ALX homeobox protein 1 {ECO:0000256|ARBA:ARBA00014029};
DE AltName: Full=Cartilage homeoprotein 1 {ECO:0000256|ARBA:ARBA00032590};
GN Name=LOC106561592 {ECO:0000313|RefSeq:XP_013981173.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_013981173.1};
RN [1] {ECO:0000313|RefSeq:XP_013981173.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_013981173.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the paired homeobox family.
CC {ECO:0000256|ARBA:ARBA00005733}.
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DR RefSeq; XP_013981173.1; XM_014125698.1.
DR AlphaFoldDB; A0A1S3KR50; -.
DR STRING; 8030.ENSSSAP00000011272; -.
DR PaxDb; 8030-ENSSSAP00000011272; -.
DR Ensembl; ENSSSAT00000012005; ENSSSAP00000011272; ENSSSAG00000005590.
DR GeneID; 106561592; -.
DR KEGG; sasa:106561592; -.
DR CTD; 8092; -.
DR OMA; SSPCGDQ; -.
DR OrthoDB; 5400675at2759; -.
DR Proteomes; UP000087266; Chromosome ssa10.
DR Bgee; ENSSSAG00000005590; Expressed in nose and 2 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR003654; OAR_dom.
DR PANTHER; PTHR24329:SF359; ALX HOMEOBOX PROTEIN 1; 1.
DR PANTHER; PTHR24329; HOMEOBOX PROTEIN ARISTALESS; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR Pfam; PF03826; OAR; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
DR PROSITE; PS50803; OAR; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT DOMAIN 127..187
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DOMAIN 306..319
FT /note="OAR"
FT /evidence="ECO:0000259|PROSITE:PS50803"
FT DNA_BIND 129..188
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
SQ SEQUENCE 326 AA; 36771 MW; 67AAADA809919DD0 CRC64;
MEYMNDKFAL KSQAIKGSDY YMGSGGALDQ VMESLDSVQY YSKTSPKCVQ AFGIQSSEHH
SRMERSSPCG DQHANYGVQK TEDTLHADLG RSIDNCCNLR ASPATACQEK TDLDEMGDKC
DSNVSSSKKR RHRTTFTSTQ LEELEKVFQK THYPDVYVRE QLAMRTELTE ARVQVWFQNR
RAKWRKRERY GQIQQAKSHF AATYDISVLP RTDSYSQIPN NLWPSPAPSG SVVSSCMLPR
GSPPCVNSYS HSPRSAADHG YVGFPNQQNQ FGHVSLNNFF TADSLLTPSP NGHPFETKPE
FERRSSSIAV LRMKAKEHAA NISWAM
//
