ID A0A1S3KRN9_SALSA Unreviewed; 730 AA.
AC A0A1S3KRN9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Solute carrier organic anion transporter family member {ECO:0000256|RuleBase:RU362056};
GN Name=LOC106561698 {ECO:0000313|RefSeq:XP_013981381.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_013981381.1};
RN [1] {ECO:0000313|RefSeq:XP_013981381.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_013981381.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362056};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU362056}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the organo anion transporter (TC 2.A.60) family.
CC {ECO:0000256|ARBA:ARBA00009657, ECO:0000256|RuleBase:RU362056}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU362056}.
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DR RefSeq; XP_013981381.1; XM_014125906.1.
DR AlphaFoldDB; A0A1S3KRN9; -.
DR STRING; 8030.ENSSSAP00000050485; -.
DR PaxDb; 8030-ENSSSAP00000050485; -.
DR Ensembl; ENSSSAT00000078762; ENSSSAP00000050485; ENSSSAG00000046263.
DR GeneID; 106561698; -.
DR KEGG; sasa:106561698; -.
DR OMA; ESSISMW; -.
DR OrthoDB; 2874223at2759; -.
DR Proteomes; UP000087266; Chromosome ssa10.
DR Bgee; ENSSSAG00000046263; Expressed in ovary and 1 other cell type or tissue.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR002350; Kazal_dom.
DR InterPro; IPR036058; Kazal_dom_sf.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR004156; OATP.
DR NCBIfam; TIGR00805; oat; 1.
DR PANTHER; PTHR11388; ORGANIC ANION TRANSPORTER; 1.
DR PANTHER; PTHR11388:SF99; SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1C1; 1.
DR Pfam; PF07648; Kazal_2; 1.
DR Pfam; PF03137; OATP; 1.
DR SUPFAM; SSF100895; Kazal-type serine protease inhibitors; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS51465; KAZAL_2; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|RuleBase:RU362056};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362056};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362056};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362056}; Transport {ECO:0000256|RuleBase:RU362056}.
FT TRANSMEM 89..109
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 121..143
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 284..304
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 367..385
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 405..425
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 437..457
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 564..591
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 612..635
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 655..678
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT DOMAIN 55..683
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT DOMAIN 482..537
FT /note="Kazal-like"
FT /evidence="ECO:0000259|PROSITE:PS51465"
FT REGION 27..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..46
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 730 AA; 79539 MW; F8EEA7580FA6D69B CRC64;
MTKDYNRETP SPEETIIFLR KMEVPSKGRW TPDDISSTPS SSGMQRSSCS SLKMFLAALS
FAYFSKALSG SYMKSTITQL ERRFDIPSYL IGVIDGSFEI GNLLVIAFVS YFGAKLHRPK
IIAIGCVLMS FGTFLIAMPH FILGRYKFQS SVRASMNSTT TFGPCPASSA ESTQAGDKAS
ILPSVGCEQE SSVSMWIYVF LGNVLRGIGE TPVHPLGISY IDDYARSENA ALYISCVQTI
SIIGPVFGYL LGSLCAKIYV DIGYVNMETI TITPGDARWV GAWWLGYLIA GAITLMSAVP
FWFLPKSLPM PVDKQLNANC TSEQTRFIKD SPSAMEDTFR PVEPANFHQM AKEFVPTLKS
LLGSPIYITY LCVTIIQFNS LIGMVTYKPK YIEQHYGQSA SKANFLMGTV NIPAVALGMF
SGGVVMKKFK LGVMGAAKFA FGTSLLGYFL SLFFFAMGCD NAKVAGITMS YTGVEGLSYQ
QPSLFSECNS GCQCSGSDWD PVCGENGITY VSPCLAGCKS STGAGKNTVF DQCRCVAVTG
AGSQPSNQTA SLGHCPIRDS CDTMFPYFLF LSVITSFIIS LGGTPGFMLL IRCIKPEFKS
LALGVHTLAT RTLAGIPAPI YFGAIIDTTC LKWGITKCGG RGACRIYNTT AYRVVYLGLT
MGLRTVSFLL CILGFVLLGR HVKQEEKMAL TNGNVEMESE SLRKEESNNS LHCDQFVRAL
DCNPDRETRL
//
