ID A0A1S3KWQ3_SALSA Unreviewed; 260 AA.
AC A0A1S3KWQ3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=small monomeric GTPase {ECO:0000256|ARBA:ARBA00011984};
DE EC=3.6.5.2 {ECO:0000256|ARBA:ARBA00011984};
GN Name=rasl12 {ECO:0000313|RefSeq:XP_013983073.1,
GN ECO:0000313|RefSeq:XP_013983074.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_013983073.1};
RN [1] {ECO:0000313|RefSeq:XP_013983073.1, ECO:0000313|RefSeq:XP_013983074.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_013983073.1,
RC ECO:0000313|RefSeq:XP_013983074.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189; EC=3.6.5.2;
CC Evidence={ECO:0000256|ARBA:ARBA00023421};
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Ras family.
CC {ECO:0000256|ARBA:ARBA00008344}.
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DR RefSeq; XP_013983073.1; XM_014127598.1.
DR RefSeq; XP_013983074.1; XM_014127599.1.
DR STRING; 8030.ENSSSAP00000017701; -.
DR PaxDb; 8030-ENSSSAP00000017701; -.
DR GeneID; 106562635; -.
DR CTD; 51285; -.
DR OMA; CERYLAW; -.
DR OrthoDB; 2601998at2759; -.
DR Proteomes; UP000087266; Chromosome ssa11.
DR Bgee; ENSSSAG00000008430; Expressed in heart and 10 other cell types or tissues.
DR GO; GO:0003925; F:G protein activity; IEA:UniProtKB-EC.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR CDD; cd04146; RERG_RasL11_like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR001806; Small_GTPase.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR45704:SF18; PROTEIN CBG04185; 1.
DR PANTHER; PTHR45704; RAS-LIKE FAMILY MEMBER 11; 1.
DR Pfam; PF00071; Ras; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00173; RAS; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51419; RAB; 1.
DR PROSITE; PS51421; RAS; 1.
DR PROSITE; PS51420; RHO; 1.
PE 3: Inferred from homology;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266}.
SQ SEQUENCE 260 AA; 28936 MW; ABA910B3CAB0F0BA CRC64;
MSLMFGKARS CNFSAIPEGG QPEVNVVVLG VRGSGKSALT VKFLTKRFIS EYDPNLEDTY
SSEEMVDQQP VVVKVMDTAD QDGPVNCERY LSWASAFLVV YSIDNRRSFE GCQQYLEAVT
VHTKALQPKT PIILLGNKLD MERYRQVSKL DGSALASHFG CLFFEVSACL DFLSVQRVFH
EAVREARQAG GKRSPPLRPL YISEDNKPLF SLATVPPFNT PCYKELPVPA TAKLVTVKSS
RAQSKRRAPT LTLLKGFKIF
//
