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Database: UniProt
Entry: A0A1S3KX85_SALSA
LinkDB: A0A1S3KX85_SALSA
Original site: A0A1S3KX85_SALSA 
ID   A0A1S3KX85_SALSA        Unreviewed;       860 AA.
AC   A0A1S3KX85;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   05-JUN-2019, entry version 18.
DE   SubName: Full=ral guanine nucleotide dissociation stimulator-like isoform X1 {ECO:0000313|RefSeq:XP_013983326.1};
GN   Name=LOC106562829 {ECO:0000313|RefSeq:XP_013983326.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii;
OC   Salmoniformes; Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_013983326.1};
RN   [1] {ECO:0000313|RefSeq:XP_013983326.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_013983326.1};
RG   RefSeq;
RL   Submitted (JUN-2017) to UniProtKB.
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DR   RefSeq; XP_013983326.1; XM_014127851.1.
DR   GeneID; 106562829; -.
DR   KEGG; sasa:106562829; -.
DR   KO; K08732; -.
DR   OrthoDB; 940219at2759; -.
DR   Proteomes; UP000087266; Genome assembly.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   CDD; cd00155; RasGEF; 1.
DR   CDD; cd06224; REM; 1.
DR   Gene3D; 1.10.840.10; -; 1.
DR   InterPro; IPR000159; RA_dom.
DR   InterPro; IPR015758; RalGDS.
DR   InterPro; IPR008937; Ras-like_GEF.
DR   InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR   InterPro; IPR023578; Ras_GEF_dom_sf.
DR   InterPro; IPR001895; RASGEF_cat_dom.
DR   InterPro; IPR036964; RASGEF_cat_dom_sf.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   PANTHER; PTHR23113; PTHR23113; 1.
DR   PANTHER; PTHR23113:SF35; PTHR23113:SF35; 1.
DR   Pfam; PF00788; RA; 1.
DR   Pfam; PF00617; RasGEF; 1.
DR   Pfam; PF00618; RasGEF_N; 1.
DR   SMART; SM00314; RA; 1.
DR   SMART; SM00147; RasGEF; 1.
DR   SMART; SM00229; RasGEFN; 1.
DR   SUPFAM; SSF48366; SSF48366; 1.
DR   SUPFAM; SSF54236; SSF54236; 1.
DR   PROSITE; PS50200; RA; 1.
DR   PROSITE; PS50009; RASGEF_CAT; 1.
DR   PROSITE; PS50212; RASGEF_NTER; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000087266};
KW   Guanine-nucleotide releasing factor {ECO:0000256|PROSITE-
KW   ProRule:PRU00168, ECO:0000256|SAAS:SAAS01081641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT   DOMAIN      125    255       N-terminal Ras-GEF. {ECO:0000259|PROSITE:
FT                                PS50212}.
FT   DOMAIN      292    557       Ras-GEF. {ECO:0000259|PROSITE:PS50009}.
FT   DOMAIN      744    831       Ras-associating. {ECO:0000259|PROSITE:
FT                                PS50200}.
FT   REGION      572    596       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A1S3KX85}.
FT   REGION      642    667       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A1S3KX85}.
FT   REGION      690    724       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A1S3KX85}.
SQ   SEQUENCE   860 AA;  96259 MW;  4B7FBE2F7F5BC2B1 CRC64;
     MVYLTVAQCE GRIIKLGSPD VMFDASTWRI RNIWDAVKLE VAGNVSPVVL HSFTQLDPDL
     PLLENATQEI GEEVEDGVVY TITLRKVQML HHHHHPGHHI GGSGAIKGQR WLGVDASLSL
     YETCKVRTIK AGTLEKLVEY MVAAFRGNDS TYVTIFLCTY RSFASTKQVL DLLLNRYAKL
     QHLPGSEGHR LTHDDRTDLR NTISSILGAW LDQYSEDFWN PPEYSCLRRL ISYLHLNFPG
     SDLERRACNL LAHFDRRQLQ EPESESLDHG GYPFTLLENG YEDDRLDFLN FDPAVVAEQF
     TLMDAELFKK VVPYHCLGSI WSQRDKKGKE HLAPTIRATV TQFNCVTNCV IATCLSERLL
     KPTQRAKLVE RWIEVARECR ILKNFSSLRA ILSALQCNPV HRLKRTWDEV SRENFRIFHE
     LSEIFSDENN HSLSRELLIK EGTSKFATLE INPKRAQKRQ QQPRDLSVMQ GTIPYLGTFL
     TDLVMMDTAM KDYLDGGLIH FEKRRKEFEV IAQIKLLQLA CNNYNFTRNK RFRQWFSGVD
     KLTEAESYSQ SCEIEPLSES ASNTLKKKNT GIIKRWSDRQ PASSEPGYCS AGSSHSKSFD
     QLRYAPCLGG SSGGGGGDGA DSLSVTSAGS SSSDVEEINI SFISDSPDAH ERKTSTPSVK
     HSNSTLGKCG PLPDLAPTFW ESTSLSSLDA SGVGSGSGSS SASSSSMSST PVVGAGSRSH
     KRSVSGVSNY SSLSLPLYNQ QVDDCCIIRV SLDVDNGNMY KSILVTSQDK TPAVIRKAMV
     KHNLDRERAE DYELLQKISE EKELKIPDNA NVFYAMNSSA NYDFVLKKHG FPKVCRTKHV
     ASSTLPRMKQ KGLKIGKGIF
//
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