ID A0A1S3L316_SALSA Unreviewed; 1572 AA.
AC A0A1S3L316;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Rapamycin-insensitive companion of mTOR-like isoform X3 {ECO:0000313|RefSeq:XP_013985195.1};
GN Name=LOC106563815 {ECO:0000313|RefSeq:XP_013985195.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_013985195.1};
RN [1] {ECO:0000313|RefSeq:XP_013985195.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_013985195.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RICTOR family.
CC {ECO:0000256|ARBA:ARBA00008878}.
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DR RefSeq; XP_013985195.1; XM_014129720.1.
DR GeneID; 106563815; -.
DR OrthoDB; 90320at2759; -.
DR Proteomes; UP000087266; Chromosome ssa01.
DR GO; GO:0031932; C:TORC2 complex; IEA:InterPro.
DR GO; GO:0031929; P:TOR signaling; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR028268; Pianissimo_fam.
DR InterPro; IPR028267; Pianissimo_N.
DR InterPro; IPR029453; Rictor_IV.
DR InterPro; IPR029451; RICTOR_M.
DR InterPro; IPR029259; RICTOR_phospho.
DR InterPro; IPR029452; RICTOR_V.
DR PANTHER; PTHR13298; CYTOSOLIC REGULATOR PIANISSIMO; 1.
DR PANTHER; PTHR13298:SF11; RAPAMYCIN-INSENSITIVE COMPANION OF MTOR; 1.
DR Pfam; PF14663; RasGEF_N_2; 1.
DR Pfam; PF14666; RICTOR_M; 1.
DR Pfam; PF14664; RICTOR_N; 1.
DR Pfam; PF14665; RICTOR_phospho; 1.
DR Pfam; PF14668; RICTOR_V; 1.
DR SMART; SM01303; RasGEF_N_2; 1.
DR SMART; SM01307; RICTOR_M; 1.
DR SMART; SM01308; RICTOR_N; 1.
DR SMART; SM01309; RICTOR_phospho; 1.
DR SMART; SM01310; RICTOR_V; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT DOMAIN 1..287
FT /note="Rapamycin-insensitive companion of mTOR N-terminal"
FT /evidence="ECO:0000259|SMART:SM01308"
FT DOMAIN 371..590
FT /note="Rapamycin-insensitive companion of mTOR middle"
FT /evidence="ECO:0000259|SMART:SM01307"
FT DOMAIN 768..840
FT /note="Rapamycin-insensitive companion of mTOR"
FT /evidence="ECO:0000259|SMART:SM01310"
FT REGION 854..894
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 945..980
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1011..1096
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1118..1160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1322..1349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 866..894
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 953..969
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1062..1096
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1572 AA; 175256 MW; 91DC53E2AB44467E CRC64;
MITVNALLFP SSVTNSLIAV GKDGLQERDR MVRVCIAIIC ELAVKNPVVV AQRSGLSTIL
KNVIDCQLSR INEALITTIL HLLNHPHTRQ YVRSDVELEQ ILAPYTDFHY RHNADTSEGQ
LKEDREARFL ASKMSIVASF RSWSGIINLC KSGNSGIQSL IGLLCIPNVE VRKGLLEVMY
EIFRLPMPVA TADFIEALVS VDPSRFQDSW RLSDGFVASE AKCILPHRAR SRPDLMDNYL
ALVLSAFIKS GLLEGLIEVI TSTDDNNSVR ATILLGELLH MANTILPHSH SHHLHCLPTL
IHKAASFDIA QEKRLRASAA VNYLKRFHEK KKKGPKPNSL YLDHIIRKSK SSHYCRDQHF
RPQRDIFVIK DTEDALMMNL RDSHILNHKE NLDWNWVLIA TILKWPNVNL RSNKDEQIHK
FVRRLLFFYK PSSKLYASLE LDHSKARQLT VVGCQFIEFL LESDEDGQVY LEDLVKDIVQ
WLSSSSGLKP DRSLQSNGLL TTLSQHYFLF LGTLSSHPHG VKMLEKCGVF QCLLSICTLK
NQDHPLKLTV STLDYSRDGL SRVILSKILT AATDNCRLYA TKHLRVLLRA NVEFFSNWGI
ELLVTQLHDR NKSISMEALD ILDEACEDKA NLHALIQMKP ALTHLGDKGV LLLLRFLSIP
KGFSYLNERG YVTKQLEKWQ KEYNLKYVDM IEEQLNEALT TYRKPVDGDN YVRRSNQRLQ
RPNVYLPVHL YGQLVHDKTG CHLLEVQNVV PDLSYTVRSP MLDKWEGIKQ LKAALWALGN
IGSSNWGLNL LQEEGVIPDI VVLALHCEVL SVRGTCLYVL GLISKTRQGC DMLKQHGWDA
VRHSRRTLWP VVPDDMEPHP NPPSLLSSVP SSLSLASDST SSMHNSESDS TQPSMYIMDD
ERLENCDLSD DPPMYMRPKY KDRSPFTLLA SSRFRNRLLH SLSLSGKKLR SNSDPKGIPR
GRRGGVEGQQ GRKRTVTEPS YTFGSSDVFP IYNDSHLPKS PSVNLETSFV GSKASENRGS
TPSIGEGRLP GRSVAVGGSG VGENQREQAS RERLVGYGGG AQFKSRSQSF NTDTTTSGIS
SMSSSPSRET LPSTIDTDGV SLNSVISAQT IQTLTSLTPQ PHTAQPHTAH LSSLSKSSSA
SLVPPGSSHT LPRRAQSLKS PSLTTLSGLT DCSLMYSNSR DALGYATLKY ASCRDTYASQ
RDALGYATLK RLQQQRIHSS LSHSEALASP VKDMLFTDTI NMKTGSLDSR LTPRRFLKAL
SFASLDKEDL LSPISQTTLQ RSSSVRSMVS SATYGSSDDF IGLALPVDIN NMFQIKETPY
FQKRTSPPSE DRSAKFFSGD SDGPSPHSRH AVLRSQLSIT ELMGVSRAEQ QQLLGSEETG
LQEHNDDNCL YCTGLTLLGF SASDSHPDLT EDHPFSEWCS PPVQNHLEVM AQTKLSGVSG
CNDAMSQDSP GSTRSTELVL GVKSIPEDAP AGRVLLRKEV LRLVVNLSSS VGTKGHETNL
LTIKEKFPYA FDDICLYSEV SYLLAHCMFR LSARRFIQEL FQDVPFIPMY EEAESILSMP
PKNGPTDPPA EP
//
