ID A0A1S3L5L8_SALSA Unreviewed; 214 AA.
AC A0A1S3L5L8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Calcium-binding protein 7-like {ECO:0000313|RefSeq:XP_013985809.1};
GN Name=LOC106564295 {ECO:0000313|RefSeq:XP_013985809.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_013985809.1};
RN [1] {ECO:0000313|RefSeq:XP_013985809.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_013985809.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBUNIT: Interacts with PI4KB. This binding competes with FREQ/NCS1
CC binding in a calcium-dependent manner. {ECO:0000256|ARBA:ARBA00038636}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004521};
CC Single-pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004521}.
CC Cytoplasm, perinuclear region {ECO:0000256|ARBA:ARBA00004556}. Golgi
CC apparatus, trans-Golgi network membrane
CC {ECO:0000256|ARBA:ARBA00037801}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00037801}.
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DR RefSeq; XP_013985809.1; XM_014130334.1.
DR AlphaFoldDB; A0A1S3L5L8; -.
DR STRING; 8030.ENSSSAP00000010962; -.
DR PaxDb; 8030-ENSSSAP00000010962; -.
DR Ensembl; ENSSSAT00000011675; ENSSSAP00000010962; ENSSSAG00000005442.
DR GeneID; 106564295; -.
DR KEGG; sasa:106564295; -.
DR CTD; 556082; -.
DR OMA; ECHVDID; -.
DR OrthoDB; 3936962at2759; -.
DR Proteomes; UP000087266; Chromosome ssa01.
DR Bgee; ENSSSAG00000005442; Expressed in camera-type eye and 3 other cell types or tissues.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR001751; S100/CaBP7/8-like_CS.
DR PANTHER; PTHR46311:SF2; CALCIUM-BINDING PROTEIN 7; 1.
DR PANTHER; PTHR46311; CALCIUM-BINDING PROTEIN 8-RELATED; 1.
DR Pfam; PF13499; EF-hand_7; 1.
DR SMART; SM00054; EFh; 2.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00018; EF_HAND_1; 2.
DR PROSITE; PS50222; EF_HAND_2; 2.
DR PROSITE; PS00303; S100_CABP; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 186..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 35..70
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 71..106
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 214 AA; 24535 MW; E653C7423C2FF43F CRC64;
MPVRMPVRTT RFMYKGNCTI PDILSYRTPI NLPEDEVEEI REAFKVFDRD GNGYISKQEL
GVAMRSLGYM PNEVELEIII QRLDMDGDGQ VDFEEFVALL GPKLVAAGMP DKFHGADFDS
VFWKCDMSKL TVDELKRLLY DTFCDHLTMK DIENIIMTEE SHLDSQECQV DIDTSPTQQK
HTCVRKSLIC AFAFAFIISV MLIAANQMLR RGMK
//
