ID A0A1S3L5Z8_SALSA Unreviewed; 890 AA.
AC A0A1S3L5Z8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Phosphoinositide 3-kinase regulatory subunit 5 {ECO:0000256|ARBA:ARBA00040195};
GN Name=LOC106564678 {ECO:0000313|RefSeq:XP_013986368.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_013986368.1};
RN [1] {ECO:0000313|RefSeq:XP_013986368.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_013986368.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Membrane {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_013986368.1; XM_014130893.1.
DR AlphaFoldDB; A0A1S3L5Z8; -.
DR STRING; 8030.ENSSSAP00000102825; -.
DR PaxDb; 8030-ENSSSAP00000102825; -.
DR Ensembl; ENSSSAT00000208238; ENSSSAP00000126694; ENSSSAG00000075389.
DR GeneID; 106564678; -.
DR KEGG; sasa:106564678; -.
DR OMA; HELINDC; -.
DR OrthoDB; 5349388at2759; -.
DR Proteomes; UP000087266; Chromosome ssa12.
DR Bgee; ENSSSAG00000075389; Expressed in spleen and 9 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005944; C:phosphatidylinositol 3-kinase complex, class IB; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046935; F:1-phosphatidylinositol-3-kinase regulator activity; IEA:InterPro.
DR InterPro; IPR019522; PIK3R5/6.
DR PANTHER; PTHR15593; PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR15593:SF2; PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 5; 1.
DR Pfam; PF10486; PI3K_1B_p101; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT REGION 316..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 403..435
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 326..348
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 412..435
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 890 AA; 99314 MW; 99BC188A694F531A CRC64;
MQHTSCTEDR IQHALDRCLD GLRPSPTAPQ PWNVLMCSAG QSLNRWSLEE LVKRDPENFL
ILLQQILRKT REVQDQCQYE RVAPLAIMFS STLLQTPFCP PATELLEEAC EVFGCFLTWP
EPYCSVCKGL LSTLHQELKA PGISYHRLVR EEQGLATSKH RSKTMTVLLM NPGEVPPEFL
SVADQLSSIQ RSQRETYITL VKHAYQATLG TKYPLASIHK ALQVKSLEVL VEIFSMVTDV
LEMAAAMDDP VKGRDHVTQG LERLRERMGV PASNVRKSDG MLQTLPLPTA KCYMFHWDKD
NFDILNTILE NEHDLTGFQT SSGQGDVEDE EGEEGAEFDL EEEEGEKEEG EKEFVRRHVG
DNGWSVDHRA STFSTLSTAS KDSMYSNLSE SYTPSILSVT SGIDSDFYED PEDATSTSST
SPLERSPSSG KSTKALARRS QHFSRFFKTK TQSLTRAKSL GSPDAKDFVP VRSKRSNSLP
QQVHLRSPDS LFQSPCTPQA LKHVCFRRRP ILSSDEEGNS NATTLRVVVF GADHVAGKVA
RAYSNLRQRE NVCPSLSRAF RLQFFFVPVK RDGVVRCPSP RCPSPGGQSA SPRRGSTSCT
ELNILGTEDS TNDIARFIGM LDPWYERNTL SLLSLPANVV GQQTSKIESE LYDSSYEDRL
PILADLVLYY CRHATRPALM QLYQAEMTLA GGERRTEVFI HSLELGHTAG TRAIKAMGAA
SKRFGIDGDR EAVPLMLEVV YNTVVISGRS QWTKKDKVCT SINLTKACKN PEELDSKMEC
LQLTMTEVLK RQNSNKSKKG YNQQLSITEV KVDKVQVSGT GNTTFAVCLD QDEKKIFQGV
TRCEVSVCYK PDSSTDWRLD QGLSAQIQPL HPTFCSLLCL PIATFSGAQP
//
