ID A0A1S3LCB8_SALSA Unreviewed; 598 AA.
AC A0A1S3LCB8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Ras association domain-containing protein 5-like isoform X2 {ECO:0000313|RefSeq:XP_013988603.1};
GN Name=LOC106565716 {ECO:0000313|RefSeq:XP_013988603.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_013988603.1};
RN [1] {ECO:0000313|RefSeq:XP_013988603.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_013988603.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
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DR RefSeq; XP_013988603.1; XM_014133128.1.
DR AlphaFoldDB; A0A1S3LCB8; -.
DR GeneID; 106565716; -.
DR OrthoDB; 4260488at2759; -.
DR Proteomes; UP000087266; Chromosome ssa12.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0048468; P:cell development; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd20886; C1_RASSF5; 1.
DR CDD; cd21892; SARAH_RASSF5; 1.
DR Gene3D; 1.20.5.110; -; 1.
DR Gene3D; 3.30.60.20; -; 1.
DR InterPro; IPR046349; C1-like_sf.
DR InterPro; IPR002219; PE/DAG-bd.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR033614; RASSF1-6.
DR InterPro; IPR011524; SARAH_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR22738:SF9; RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 5; 1.
DR PANTHER; PTHR22738; RASSF; 1.
DR Pfam; PF00130; C1_1; 1.
DR Pfam; PF16517; Nore1-SARAH; 1.
DR Pfam; PF00788; RA; 1.
DR SMART; SM00109; C1; 1.
DR SMART; SM00314; RA; 1.
DR SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50200; RA; 1.
DR PROSITE; PS50951; SARAH; 1.
DR PROSITE; PS00479; ZF_DAG_PE_1; 1.
DR PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 291..338
FT /note="Phorbol-ester/DAG-type"
FT /evidence="ECO:0000259|PROSITE:PS50081"
FT DOMAIN 461..547
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT DOMAIN 549..596
FT /note="SARAH"
FT /evidence="ECO:0000259|PROSITE:PS50951"
FT REGION 101..253
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 341..381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 433..453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 137..158
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 174..197
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 211..225
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 341..358
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 359..381
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 598 AA; 66060 MW; 5C03CA769C9BEAD8 CRC64;
MPGSRFNLVD IHRTHTDTHT LLGHCISSRA MASVVVVGPR QHRPAPDQEF FFKEITATGK
KKITLPRKYS LGNMVTRKIS VKRECGSVSV LSAVTATPLN PSLTPENQRA AAEVGGGNPG
VRSGAQPGLV PRSLDIESDS SRPDCGHTER DTTAGREDTG QSGRRASGND YADDGGSSLK
TVTSVRSSTS ANEQIADAKC DRSSAPTNGH TDAHSHRDRP VRMRASHSLP GETTGPGTKG
DTGGPPMERL TQGRTGVVKL ARTEPHRKEA WSIFASQDQE DPRVRAQTGE GHLFWTRTVT
QDWCDVCNQP INAQQALKCK NCSYTCHLEC EGRVQLDCNQ RDSNPQETPS PRRHCSTPPQ
NKNEVKEEQE GGPKALSEKE VRARIEDYNS NVSENGMKLA ADGLYTGFIK VHLRLSRPVT
VLAVEGAGLE EQSGKADRRG RPMTVSEGQV GEGAGLSDKR TSFYLPRDCV KQLHISSTTT
VREVIQGLLK KFMVLDNPRK FALYRQTHRD GQDLFQKLPL VECPLSLRLV AGPDPELLSF
VLKENETGEV EWHAFSVPEL QNFLVILEKE ETERVRLVEQ RFTVYRQRLQ KALCEHQP
//
