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Database: UniProt
Entry: A0A1S3LCZ5_SALSA
LinkDB: A0A1S3LCZ5_SALSA
Original site: A0A1S3LCZ5_SALSA 
ID   A0A1S3LCZ5_SALSA        Unreviewed;      2787 AA.
AC   A0A1S3LCZ5;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   16-JAN-2019, entry version 11.
DE   SubName: Full=inositol 1,4,5-trisphosphate receptor type 1-like isoform X9 {ECO:0000313|RefSeq:XP_013988695.1};
GN   Name=LOC106565749 {ECO:0000313|RefSeq:XP_013988695.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii;
OC   Salmoniformes; Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_013988695.1};
RN   [1] {ECO:0000313|RefSeq:XP_013988695.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_013988695.1};
RG   RefSeq;
RL   Submitted (JUN-2017) to UniProtKB.
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DR   RefSeq; XP_013988695.1; XM_014133220.1.
DR   GeneID; 106565749; -.
DR   OrthoDB; 94996at2759; -.
DR   Proteomes; UP000087266; Genome assembly.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; IEA:InterPro.
DR   GO; GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; IEA:InterPro.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR000493; InsP3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   PANTHER; PTHR13715; PTHR13715; 2.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   PRINTS; PR00779; INSP3RECEPTR.
DR   SMART; SM00472; MIR; 4.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF48371; SSF48371; 1.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000087266};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000313|RefSeq:XP_013988695.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2310   2332       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2344   2362       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2390   2408       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2428   2455       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2476   2498       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2607   2630       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      112    166       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      173    223       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      231    287       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      294    383       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      389    445       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   COILED     2724   2765       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   2787 AA;  316842 MW;  AB6E86CF45683C77 CRC64;
     MSDKMSSFLH IGDICSLYAE GSTSGFISTL GLVDDRCVVQ PDTGDLNNPP KKFRDCLFKL
     CPMNRYSAQK QFWKAAKPGG NSTTDTVLLN KLHHAADLEK KQNESENRKL LGTVIQYGNV
     IQLLHLKSNK YLTVNKRLPA LLEKNAMRVT LDSAGNEGSW FYIQPFYKLR SLGDSVVIGD
     KVVLNPVNAG QPLHASSHQL VDNPGCNEVN SVNCNTSWKV VLFMKWSDNK EIILKGGDVV
     RLFHAEQEKF LTCDDFKKKE YVFLRTTGRQ SATSATSSKA LWEVEVVHHD PCRGGAGYWN
     SLFRFKHLAT GSYLAAEVNP DYVEECPEPR SSVVDFVPFN FQLDSDHEAL RARLRTPQER
     VMYQLVSVPD GMDISSIFEL DPTTLRGGDS LVPRNSFVRL RHLCTNTWVH STNNPIDKEE
     EKPVMLRIGT SAVKEDKEAF AIVPVPPAEV RDLDLANDAS KVLASIAGKL ERGTITQNER
     RFVTKLLEDL VFFVCDIPNT GQDVLEIMVN KPNRERQKLM REQNILKQIF KLLQAPFTDS
     GDGPMLRLEE LGDQRHAPFR HICRLCYRVL RHSQQDYRKN QEYIAKQFRF MQKQIGYDVL
     AEDTITALLH NNRKLLEKHI TAAEIDTFVT LVRKNREPRF LDYLSDLCVS MNKSIPVTQE
     LICNAVLDPS NADILIETKL VLSRFEIEAV TIGEAPVETE EDEEEVWLFW RDNLKEIRSK
     SVRELAQDAK EGQKEDQEVV SYYRYQLNLF ARMCLDRQYL AINKISGQLD VDLILRCMSD
     EDLPYDLRAS FCRMMLHMHV DRDPQEQVTP VKYARLWSEI PSKIAIGDYD NDGTTRDEIK
     ERFCLTMEFV ENYLMSVVSQ NIPFDDREKN KLTFEVVNLA RNLIYFGFYN FSDLLRLTKI
     LLNILDCVHV STIYPVTKLE KGEEKQVSTG SNVMKSIHGV GELMTQVVLR GGGFLPVTPT
     HQPEEGVVKT QTEPEREDIM VMDTKLKIIE ILQFILNVRL DYRISCLLCI FKREFDESNP
     QGDGTPSSAS QDGNNMTGAL DFENIEEQAE AIFGGSEENT PLDLDDHGGR TFLRVLLHLT
     MHDYPPLVSG ALHLLFRHFS QRQEVLMAFK QVQLLVTSQD VDNYKQIKSD LDQLRSIVEK
     SELWVYKRQG DDDGGDGPSE SDHKKKGDSG SSDKKKTETT SSYNYRVMKE ILLRLSKLCV
     QEGASGKKSK KQQQRLLRNM GAHSVVLELL QIPYEKGEDV RMQEIMKLAH EFLQNFCAGN
     QQNQILLHKH INLFLNPGIL EAITMQHIFM NNFQLCSEIN ERVVQHFVHC TETHGRHVQY
     LKFLQTIVKA ENKFIKKCQD TVMAELVNSG EDVLVFYNDR ASFQTLVTMM RSERDRMDEN
     SALRYHIHLV ELLAVCTEGK NVYTEIKCNS LLPLDDIVRV VTHEDCIPEV KIAYINFLNH
     CYVDTEVEMK EIYTSNHMWK LFENFLVDIC RVCNNTSDRK HADTVLEGYV TETVMSIVTT
     FFSSPFSDQS TSLQTRQPVF VQLLQGVFRV FHCNWLTPTQ KASVEVCIKV LSDVAKSRAI
     AIPVDLDSQV NNLFVKSNNV VTKSILSWRL SAKNAPRRDS NATTSVSYRN IIERLQDIVS
     ALEDRLHPLV QAELSVLVDV LHRPELLFPE NTDARRKCES GGFISKLIKH TKQLLEENEE
     RLCIKVLQTL REMMTKDRGY GEKHIAFDDE MDVAELAPPP AEPDVPAADE LDPNQPEKQL
     EDQRRGEALR QILVNRYYGN IKPGARRDSV TTFINGPVPP GTEGKPRAVV SSGAAAARGE
     LTLHEVQCRL DKEGASDLVI DLIMNATSDR IFQESILLAI ALLEGGNTVI QKSFFMRLTG
     ENKSEMFFKV FYERMKLAQQ EIKATVTVNT SDLGSKKKDE EPPDKDTPTA KGKKGKVVAM
     VAVAAVTEEV KEQLVEASTV TKKAFTTYRR EAEAEEHLAA AECQGPASTP DDQEGEMSVI
     ITIMQPILRL MQLLCENHNR ELQNFLRCQN NKNNYNLVCE TLQFLDCICG STTGGLGLLG
     LYINEKNVGL INQTVESLTE YCQGPCHDNQ NCIATHECNG IDIIIALILN DINPLGKKRM
     DLVLELKNNA SKLLLAIMES RHDSENAERI LYNMRPKELV EVIKKAYMQG EVEPEEPAEE
     DEDGEEEHAA SPRNVGHNIY ILAHQLARHN KELQAMLKTY GEGDDALEFY AKHTAQIEIV
     RLDRTMEQIV FPVPNICEFL TNESKLRVYY TTERDEQGSK INDFFLRSED LFNEMNWQKK
     LRGTQEPTTG NANTVPSQPI LYWCSRNMSF WSSISFNLAV LMNLLVAFFY PLEGISRGTL
     DGHLSALLWI AMLVSLAIVI ILPQPHGVRV LIASTILRLI FSVGLEPTLF LLGAFNVGNK
     MIFLMSFVGN RGTFTRGYKA MIMDVEFLYH LLYLIICSLG VFVHVFFYSL LLFDLVYREE
     TLLNVIKSVT RNGRSILLTA VLALILVYLF SIVGYIFFQD DFLLNIDRIP NKTLESGASM
     VGDFLSAGVC RKDSGENCST EAVMDAAIAT QPSAVVIEDK ERSCDSLLMC IVTVLSHGLR
     SGGGVGDVLR KPSKEEPLFA GRVIYDLLFF FLVIIIVLNL IFGVIIDTFA DLRSEKQKKE
     EVLKTTCFIC GLERDKFDNK TVTFEEHIKV EHNMWHYLFF IVLVKVKDST EYTGPESYVA
     EMIREHNLDW FPRMRAMSLV CSDADGEQNE IRSLQEKLES TMKLVSNLSG QLTELKEQMT
     EQRKQKQRIG LLGHPQHPQH ANPQQTA
//
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