ID A0A1S3LDC3_SALSA Unreviewed; 767 AA.
AC A0A1S3LDC3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Rap1 GTPase-activating protein 1-like isoform X2 {ECO:0000313|RefSeq:XP_013988962.1};
GN Name=LOC106565868 {ECO:0000313|RefSeq:XP_013988962.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_013988962.1};
RN [1] {ECO:0000313|RefSeq:XP_013988962.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_013988962.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_013988962.1; XM_014133487.1.
DR AlphaFoldDB; A0A1S3LDC3; -.
DR STRING; 8030.ENSSSAP00000078008; -.
DR PaxDb; 8030-ENSSSAP00000078008; -.
DR OMA; MIEKMQX; -.
DR OrthoDB; 25782at2759; -.
DR Proteomes; UP000087266; Chromosome ssa12.
DR Bgee; ENSSSAG00000064378; Expressed in brain and 12 other cell types or tissues.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR Gene3D; 6.10.140.210; -; 1.
DR Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR InterPro; IPR035974; Rap/Ran-GAP_sf.
DR InterPro; IPR000331; Rap/Ran_GAP_dom.
DR PANTHER; PTHR15711:SF67; GTPASE ACTIVATING PROTEIN RAP1-GAP; 1.
DR PANTHER; PTHR15711; RAP GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF21022; Rap-GAP_dimer; 1.
DR Pfam; PF02145; Rap_GAP; 1.
DR SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR PROSITE; PS50085; RAPGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT DOMAIN 233..449
FT /note="Rap-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50085"
FT REGION 495..542
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 556..626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 639..680
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 696..767
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 495..522
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 576..626
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 641..657
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 696..715
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 720..751
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 767 AA; 85512 MW; 610086998A017110 CRC64;
MSQRKRSFTF GAYGGVDKTF SRTRSLCKQD GRIPRISDTL EPLLSHSHPP YCAHSLSKGS
RMDEQRCTFP PPLKTEEDYI PYPSVHEVLG RRSPFPLILL PQFGGYWIEG TNHKPSATPE
PEQKPCAASH IKLETNSTAK IYRKQFMGKE HFNYYSMDIG LGHLVFSMKY DVIGDQEHLC
LLLRTKLKTH HDVIPISCLT EFPNVVQMAK LVFEEVNVDR FYPVLYPKAS RLIVTFDEHV
ISNKFKFGVI YQKFGQTTEE ELFGNSDESP AFVEFLEFLG DKIELHDFKG FRGGLDVTHG
QTGTESVYTN FHNKEIMFHV STKLPYTEGD SQQLQRKRHI GNDIVAILFQ EENTPFVPDM
IASNFLHAYV VVQVENACSD NVTYKVSVTA RDDVPFFGPA LPDPAIFKKG HEFHEFLFTK
LINAEYACYK AEKFAKLEER TRSALLETLY EELHINSQSM MGLGGDEDKL ENGAGGGGGF
FESFKRVIRS RSQSMDAMGL SNKKPHTVST SLSSSFTETP KTPGISLLVP GKSPSRYHGR
RGSAIGIGTI EESLIIPGKS PTRKKSGPFS ARRSSAIGIE NIQEVQERSR EVSPSTQRTP
DSGQISQDPK SENSSNQSSP EMPTTKNSLA MCCRAPSIPE AQDLSRSSSN ASSFASVVEE
HDNEGIEEYD PGLESLSFSG TSHKRDSFAY VSWVEDSVSS TSAASQGSSP APARSQQPEG
GKGEELKKAE SRDKTERSSS HSHKRHPLQE MKQAHVCSTT DAEEEQS
//
