ID A0A1S3LGN1_SALSA Unreviewed; 1513 AA.
AC A0A1S3LGN1;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Ubiquitin carboxyl-terminal hydrolase 19-like isoform X1 {ECO:0000313|RefSeq:XP_013989990.1};
GN Name=LOC106566460 {ECO:0000313|RefSeq:XP_013989990.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_013989990.1};
RN [1] {ECO:0000313|RefSeq:XP_013989990.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_013989990.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_013989990.1; XM_014134515.1.
DR KEGG; sasa:106566460; -.
DR OrthoDB; 5474185at2759; -.
DR Proteomes; UP000087266; Chromosome ssa13.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd06466; p23_CS_SGT1_like; 1.
DR CDD; cd06463; p23_like; 1.
DR CDD; cd02674; Peptidase_C19R; 1.
DR Gene3D; 2.60.40.790; -; 2.
DR Gene3D; 6.10.140.2220; -; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 2.
DR InterPro; IPR007052; CS_dom.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR001394; Peptidase_C19_UCH.
DR InterPro; IPR018200; USP_CS.
DR InterPro; IPR028889; USP_dom.
DR InterPro; IPR002893; Znf_MYND.
DR PANTHER; PTHR21646; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR PANTHER; PTHR21646:SF74; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 19; 1.
DR Pfam; PF04969; CS; 1.
DR Pfam; PF00443; UCH; 1.
DR Pfam; PF16602; USP19_linker; 1.
DR Pfam; PF01753; zf-MYND; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR SUPFAM; SSF49764; HSP20-like chaperones; 2.
DR PROSITE; PS51203; CS; 2.
DR PROSITE; PS00972; USP_1; 1.
DR PROSITE; PS00973; USP_2; 1.
DR PROSITE; PS50235; USP_3; 1.
DR PROSITE; PS01360; ZF_MYND_1; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|RefSeq:XP_013989990.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT TRANSMEM 1488..1508
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 49..139
FT /note="CS"
FT /evidence="ECO:0000259|PROSITE:PS51203"
FT DOMAIN 443..545
FT /note="CS"
FT /evidence="ECO:0000259|PROSITE:PS51203"
FT DOMAIN 661..1400
FT /note="USP"
FT /evidence="ECO:0000259|PROSITE:PS50235"
FT DOMAIN 960..1002
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 143..436
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 545..613
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1050..1168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..44
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 144..158
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 196..213
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 247..268
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 269..290
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 315..329
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 341..355
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 379..413
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 414..433
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 562..576
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1117..1138
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1513 AA; 168221 MW; AB971D8E485E1B55 CRC64;
MASSSESGRR NGGQRSADDS TSKKKQKDRA NQESREAKRA AAGANAEHKK DVFVDWKQNA
NEVIARLRCG DGVQRVEDVT TTFTDTYCQA RFPDGRQWDC HLHEEIEGSC SKVQYKEKSG
FLLLVMHKKI PFHSWPSLMQ NKKEKQPVKV EAKNGKDQKQ LPLVKPVVKP EKSVPKTADM
AELSAQTSAP PAQCEQRRGK AERGVKRIMN YKPADKPESG VKAGGEGQTK PVSVSKGDLP
QEPSAKRTVH PPKDPTSEMP RDTHSKSTSN GKPHSPTGRD LQTSTAGDNR AELLGNGHEG
TTPEVAISHT QQELKVQMED NKAPESDFKA GAEEVIIPAA TVSSAQISPK AGASTNRTER
PGEAERTDSE MLVRQPPNEA DQATETLTPT IQSGSGKPVT ATATKQAEPP NSSSTQEEKR
DRSKEEPLEM KQEEAVPEPM VNLKLLKNDS YEKGTDLMVV NVYMKGIFRE TARVIFREQD
FTLIFQTSDA NFLRLHADCG ANTVFKWQVK LRNLIQPEQS TYAFTPSRLD ITLKKRHSQR
WGGLEAPATQ GAVGGAKVAV PSAPSSQASQ PGSSKHSLPA KEEPPWVGEG KPKPPRTVDG
CLDSVSSRTV SDHVPIKQEP AVTPKPTCMV QPMTHAPPAG SQRSVEEEEE EEEKVCLPGF
TGLVNLGNTC FMNSVIQSLS NTRELRDYFH DRAFENEINC NNPLGTGGRL AIGFAVLLRA
LWKGTHHAFQ PSKLKAIVAS KASQFTGYAQ HDAQEFMAFL LDGLHEDLNR IQNKPYTETV
DSDGRLDEVG EIKVVADEAW QRHKMRNDSF IVDLFQGQYK SKLVCPVCSK VSITFDPFLY
LPVPLPQKQK VLTVFYFAKE PHKKPMKFLV SVSKENSSTA EVLESISRSV RIKAENLRLA
EVVKSRFHRI FLPSNSLDTV SSSDMLFCFE VLSKELAKER VVVLRVQQRP QVPSIPISKC
AACLKPPLSD EEKLKRCTRC YRVGYCNQVC QKKHWSSHKV LCGPNIENVG LPFLVSVPES
RLTYARLSQL LEGYSRYSVN VFQPPFQSGR TSPEVTQCLA DLPPPAETPE GVGSGEKARG
GGGGAGDSEQ EDSSLVPESP LETAQASAHP AGDPDALSTH TTDSGFIEPS SGSQDSQGEK
ETSCEKAVRP EGKAAVTGYQ QPSESASSHT SQFYITILHS NSKEQTLEEK EEAVLDLPED
SSLELVWKNN ERLKEYVLVR SKELEFEEDP GSVNETARAG HFTLEQCLNL FTRPEVLAPE
EAWYCPKCQQ HREASKQLLL WRLPNVLIIQ LKRFSFRSFI WRDKINDMVD FPIRNLDLSK
FCIGQKDDMQ QPPIYDLYAV INHYGGMIGG HYTAYARLPS AQNSQRSDVG WRLFDDSTVT
MVEESQVVTR YAYVLFYRRR NSPVERPPRL LGPLGAESPT AAGATASQAS LIWQELEQEE
EGVEEGPRGL FRPRLGRRRA ARREEGVEGQ VWRLLRQRIP HYSDDDCVRY FVLGTLAALL
ALLVNLLYRA NWG
//
