GenomeNet

Database: UniProt
Entry: A0A1S3LKT8_SALSA
LinkDB: A0A1S3LKT8_SALSA
Original site: A0A1S3LKT8_SALSA 
ID   A0A1S3LKT8_SALSA        Unreviewed;      3771 AA.
AC   A0A1S3LKT8;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   05-JUN-2019, entry version 16.
DE   SubName: Full=basement membrane-specific heparan sulfate proteoglycan core protein-like isoform X3 {ECO:0000313|RefSeq:XP_013991588.1};
GN   Name=LOC106567148 {ECO:0000313|RefSeq:XP_013991588.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii;
OC   Salmoniformes; Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_013991588.1};
RN   [1] {ECO:0000313|RefSeq:XP_013991588.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_013991588.1};
RG   RefSeq;
RL   Submitted (JUN-2017) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00124}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   RefSeq; XP_013991588.1; XM_014136113.1.
DR   GeneID; 106567148; -.
DR   OrthoDB; 414294at2759; -.
DR   Proteomes; UP000087266; Genome assembly.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   CDD; cd00112; LDLa; 4.
DR   Gene3D; 2.60.40.10; -; 13.
DR   Gene3D; 4.10.400.10; -; 4.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR   InterPro; IPR013032; EGF-like_CS.
DR   InterPro; IPR000742; EGF-like_dom.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR013098; Ig_I-set.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   InterPro; IPR013106; Ig_V-set.
DR   InterPro; IPR002049; Laminin_EGF.
DR   InterPro; IPR001791; Laminin_G.
DR   InterPro; IPR000034; Laminin_IV.
DR   InterPro; IPR036055; LDL_receptor-like_sf.
DR   InterPro; IPR023415; LDLR_class-A_CS.
DR   InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR   InterPro; IPR000082; SEA_dom.
DR   Pfam; PF00008; EGF; 2.
DR   Pfam; PF07679; I-set; 6.
DR   Pfam; PF00052; Laminin_B; 3.
DR   Pfam; PF00053; Laminin_EGF; 10.
DR   Pfam; PF00054; Laminin_G_1; 3.
DR   Pfam; PF00057; Ldl_recept_a; 4.
DR   PRINTS; PR00261; LDLRECEPTOR.
DR   SMART; SM00181; EGF; 11.
DR   SMART; SM00179; EGF_CA; 2.
DR   SMART; SM00180; EGF_Lam; 8.
DR   SMART; SM00409; IG; 13.
DR   SMART; SM00408; IGc2; 13.
DR   SMART; SM00406; IGv; 3.
DR   SMART; SM00281; LamB; 3.
DR   SMART; SM00282; LamG; 3.
DR   SMART; SM00192; LDLa; 4.
DR   SMART; SM00200; SEA; 1.
DR   SUPFAM; SSF48726; SSF48726; 13.
DR   SUPFAM; SSF49899; SSF49899; 3.
DR   SUPFAM; SSF57424; SSF57424; 4.
DR   PROSITE; PS00022; EGF_1; 4.
DR   PROSITE; PS01186; EGF_2; 3.
DR   PROSITE; PS50026; EGF_3; 4.
DR   PROSITE; PS01248; EGF_LAM_1; 6.
DR   PROSITE; PS50027; EGF_LAM_2; 8.
DR   PROSITE; PS50835; IG_LIKE; 13.
DR   PROSITE; PS50025; LAM_G_DOMAIN; 3.
DR   PROSITE; PS51115; LAMININ_IVA; 3.
DR   PROSITE; PS01209; LDLRA_1; 2.
DR   PROSITE; PS50068; LDLRA_2; 4.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000087266};
KW   Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00124,
KW   ECO:0000256|SAAS:SAAS00601599};
KW   EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW   Laminin EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00460,
KW   ECO:0000256|SAAS:SAAS00580772};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW   Repeat {ECO:0000256|SAAS:SAAS00814929};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     27       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        28   3771       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5010175357.
FT   DOMAIN      413    490       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN      550    735       Laminin IV type A. {ECO:0000259|PROSITE:
FT                                PS51115}.
FT   DOMAIN      769    818       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN      819    876       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN      881    926       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN      950   1125       Laminin IV type A. {ECO:0000259|PROSITE:
FT                                PS51115}.
FT   DOMAIN     1159   1208       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN     1209   1265       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN     1274   1322       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN     1533   1714       Laminin IV type A. {ECO:0000259|PROSITE:
FT                                PS51115}.
FT   DOMAIN     1748   1797       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN     1798   1854       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN     1854   1949       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN     1955   2029       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN     2070   2154       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN     2178   2289       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN     2301   2383       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN     2396   2480       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN     2487   2575       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN     2586   2664       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN     2673   2755       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN     2759   2842       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN     2847   2931       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN     2936   3018       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN     3024   3201       LAM_G_DOMAIN. {ECO:0000259|PROSITE:
FT                                PS50025}.
FT   DOMAIN     3197   3234       EGF-like. {ECO:0000259|PROSITE:PS50026}.
FT   DOMAIN     3237   3275       EGF-like. {ECO:0000259|PROSITE:PS50026}.
FT   DOMAIN     3281   3461       LAM_G_DOMAIN. {ECO:0000259|PROSITE:
FT                                PS50025}.
FT   DOMAIN     3457   3494       EGF-like. {ECO:0000259|PROSITE:PS50026}.
FT   DOMAIN     3496   3529       EGF-like. {ECO:0000259|PROSITE:PS50026}.
FT   DOMAIN     3554   3769       LAM_G_DOMAIN. {ECO:0000259|PROSITE:
FT                                PS50025}.
FT   REGION       62     81       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A1S3LKT8}.
FT   REGION      258    287       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A1S3LKT8}.
FT   REGION     1471   1557       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A1S3LKT8}.
FT   COMPBIAS    262    287       Pro-rich. {ECO:0000256|MobiDB-lite:
FT                                A0A1S3LKT8}.
FT   COMPBIAS   1501   1557       Polar. {ECO:0000256|MobiDB-lite:
FT                                A0A1S3LKT8}.
FT   DISULFID    222    234       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID    229    247       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID    241    256       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID    292    304       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID    299    317       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID    311    326       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID    332    344       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID    339    357       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID    351    366       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID    395    410       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID    788    797       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    847    856       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    897    906       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1178   1187       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1237   1246       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1249   1263       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1293   1302       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1767   1776       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1826   1835       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1838   1852       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   3224   3233       {ECO:0000256|PROSITE-ProRule:PRU00076}.
FT   DISULFID   3246   3263       {ECO:0000256|PROSITE-ProRule:PRU00076}.
FT   DISULFID   3265   3274       {ECO:0000256|PROSITE-ProRule:PRU00076}.
FT   DISULFID   3484   3493       {ECO:0000256|PROSITE-ProRule:PRU00076}.
FT   DISULFID   3519   3528       {ECO:0000256|PROSITE-ProRule:PRU00076}.
SQ   SEQUENCE   3771 AA;  410183 MW;  F2A5F20D406DEA48 CRC64;
     MGTRIHKVSG LIVSLIFTCH LVNVAQSSKV WGEVPLPEDL DSSRTVVQRS QRFLDDDEDF
     AANEASGDLP SGEEDGSTPE PTVVTEISTT YYRALVNFTD SIVYRPDMED IYSLSFEEIS
     DAVVDTLESE YNKISGIQTV NVVLIKKMPR QNGVDVFVEL DVGSDYNNNE NQIRNVLYGV
     VKEGTIASYI TSVQGFQFRR LGEALPLVNP MAVPVVPNPL PCMKDEHTCQ DGGCIPLEYL
     CDNRPDCNDM SDELDCDKIQ PGPVTPTPPT TTTPPIRKST RPLGPPDPLG PCKVDQATCQ
     NGECVPRDYL CDGERDCSDG SDEFRCGTPS PCEPNEFKCK NGRCALKLWR CDGDNDCEDN
     SDETNCPTRG PGDTCAPEQF VCLSDRTCIP SSYQCDEEPD CPDRSDEYGC TPPTVTSPPE
     ESIEAERGET VTFNCVAVGV PTPIITWRLN WGHIPISGRI SMTSENGRGS LTIRDVKEAD
     QGAYTCEAIN AKGLVFGIPD GVLSLTQKPG NCPDGHFSVE GRCISCFCFG ITKNCGNTGR
     YRNQINLRFT DEDDFKGVNV TYPSRPGTPP LSSTQLLINP EEEEFQLVDL SRRFLILDSF
     WTLPHQFLGN KIDSYGGSLK YKVRYTLARG ETEPEEKPDV VLTGNGQRLV YRRGNPTPSR
     EVNQKEIKFT EDNWQHSSGR QVSREDLMMT LASLESISIR TVYDNHMVSV ALSDIVMDTT
     TVEYNIHDNA KDVEECRCPP GYSGLSCEQC STGFERVSGG NFLGSCAGCN CNGHASACDP
     ISGQCLSCQH NTEGPQCDKC RPGYFGDPRR GRPDDCKPCP CPYTETSRRF SDTCFLDHDS
     QATCDACTPG YTGRRCEKCA SGYQGNPLQP NGKCFTTPNS KCDIRGTVNS NSRPCACKSN
     VVGSQCDECK SGSFHLMEDN PEGCLQCFCM GVTKQCASST WSRDQVRGGV NGQLFSLSNG
     ANTRTITDGI AQRGSSEVVY RSFSDIPNDV YYWVLPDSFR GDKVTAYGGE LRYTVRYEPR
     QRSLVIDRQP DVVLQGNGIF LEHFSQIKPL SPATVTVTFR ESAWRRADGQ PCTREHLLMA
     LADTTVFMIR ATYADNMVET SLSDIRMDIA VPHSTGNERA LEVEECACPQ GYNGPSCQEC
     DVGYTRTGSG LYLGTCERCH CNGHASGCDL ETGACLQCLH NTAGPRCERC LPGFYGNPMT
     DGPQACQSCP CPGTSPSNQY SLSCYKDADG QPTCDNCPPG FTGRRCERCA ARYTGNPQLG
     QKCIVGNNDL NGNCYNCDQR GSEGCNGNGV CRCKMNVEGP ACSNCKQGTF HLSTDNKDGC
     LSCFCMGVTQ QCSSSSHYRD QVSSVFAPGN FQGFALVNRQ LTNRISTGFT VELSTDGTQL
     SYSNFDYLGQ EPHYWQLPGA FQGDKKEAFF ARMRRAHQRD SSWTEEQLRK DASVWDIMTS
     SKGNGTSRSK RASQEQVKKL DDEIWAILSN FPAGSPPFPP SSSSERKVPS ASYRAGSRTP
     LRPPSPSSSL SGISSLVRPT SPQPASPGHS PRQQTQQRGT KNIVGPPSAP SSPRSTGASS
     QYALFYKGFS LHPDDTLYWQ LPEQFKGDKV NSYGGKLKYT ISYVAGQRGT AIEDADVQII
     GNDITLVARQ LWQRGKGTRE SRQFELVFRE ENWRRPDGMP ATREHLMMVL ADLDDILVRA
     SYYTEMRSSS ISDVSMEVAV PNYSGLAQAL EVEQCRCPPA YQGLSCQDCA PGYTRTGGGL
     YLGHCELCEC NGHSDSCHPE MGICTSCLHN TQGELCEQCA QGFYGDPTAG TPEDCQPCAC
     PHTDPDNQFS PTCESLGNGG YQCTACQPGY TGQYCERCAT GYVGNPQDRI KCRPFNTAAA
     SLVVKVYPER VLVAQGSPVT LRCQVTGPPP HYYYWSREDG RPVTNSAIRQ RQGEELHIPS
     VQPSDTGVYV CTCRDQRNTN RSRAEIVVTT VSSKPIQVTI EEPKTRSVTV GATVSFICTA
     KSQSPAYTLV WTRQGNGKLP NRAMDFNGIL TIQNVLPEDA GIYMCTGSNM FAMDEGTAVL
     YVPEASQTQM FYTTYEMLEG HGKPREGAQP VATVTPSVLT IQQGGHAEFH CTVTGNPTPA
     IEWIGGGPSN RMSPNAVVRG GVLTIPAVGR ENGGEYICKA LNTHGEHTSR AVLHVSGSQT
     VGRDPLVGHS RGQGASLPHV QVSPQRVDIN EGETLRLYCR AGGRPSPGLT WKKQEGQLSP
     QAIPSHGFQQ FKSNSLDVLQ RRIKELQASM ERTDIGTLLI PNIKSSDSGT YLCVGTNSIG
     SSEARIEVTV NKAIGGDTIS SAITIQPSIA EVQEGQSLDL NCFVPGNPPP AVTWRRESGR
     LSANHQVLGT KLRILSASPD DSGKYICLVE RGPGTPIRQA SVSVSVTATS SRLQTPIISI
     EPHSAALRQG ESASFKCRVN GGAEPIRLEW KLSNNQPLPD NVKVGHYGTV ITIADARPSN
     QGTYNCVATN LFGITQSIVS LIIRESPVAT VTPQGPVRVR MGEPINLECQ ASGEPRPSVT
     WHRLDSARNT MLSSPVPMES NAVMQVLVAR PEDSGTYVCT ARNDEGTTET RVEVIVEGAA
     QVPVTPRASV PDPLMVVVEG QSTTLRCDAH GFPVPKITWS KLRAPLPWRH KVVDNTLILP
     SVGRADAGEY ICNATNNMGT TEVTIMLDVE TPPYATSLPD DVAVRVGEVI RLQCLAHGTP
     PLLFQWTKLN GSLSTRADVQ GGDLQINLAI PEDAGTYKCV ATNKVGTSEA HAKVTVRSPL
     VVRVSPQVEV KARGSAVEFT CSAAGGLGTT LEWLKEGGAL PPNHHIKDGV LRIENLEQRN
     EGIYICRATS VHGQAQDSAK LTIQALPKVM INVRTAVQTV MVGNSVEFEC QAIGEPQPTV
     RWSRVGGPLP AHIMVKGGML KIEQVSDADA GQYRCTATNN VGSVQSQVVL HVQSLPQISA
     LPELNEVTVG SDAVLPCVAS GYPVPAIKWS KLDGELPPKC RQVVNTLTVP EVTHEDSGTY
     VCTASNKQGK VEALTTLKVH DRVMPYFTQE PLSYLTLPTI KNAYKSFSIK ISFRPDNPDG
     MIIYNGQKRT MGADFISLGL VGGRPEFRFD VGSGMATIRY PTPIKLGEFH TIEFYRNQTQ
     GSIIVDREAP VNGSSQGKFQ GLDLNEELYV GGYPNYTLLA KTAGLKTGFV GCIRKLVIQG
     DEIIFKDLER SSTGVSNCPV CTDRPCQNGG MCQDSEASLY KCSCPRGFTG SNCQHHSSLH
     CHPEACGPDA TCINRQNSLG YDCRCHLGKS GNKCMDGELV TTPLFDGLES YIAYPPLTNI
     HNDLRIEMEF KPMDLDGLMF FSVGKKMKTE DFVSLEMVDG YVQFCYELGT GQAVLRSPEP
     VTLGQWHRLE AGRLDKDGSL TVDGGREVRR SSPGKAQGLN IHTPMYLGGV PNIEIVPKAL
     NISDMFDGCI GVVSINGKKV DLSYSFTESM AIVQCKDNSP CDRNPCLNGA RCMPSAEYEY
     QCLCKDGFEG ERCEVVRDTC QSSDQCQNGG SCVNGHCVCP LGFNGPTCGQ SQVSSFAEAL
     WNLEGSGGND APIEYAAQFY DNGYLSLPKT IFPRSGPDAP ETIEMELKVN TTSKEGLILW
     QGVEPFNGAS HFRKMHASKK VSTSPKHLEL GDQGKGKDFI SLGLQNGHLV FSYQLGSGES
     QIQSREPIND GRWHKVTAVR TGKQGYIQID GAAIQRGQSQ GKSIMVNTKG NVYLGGAPDI
     SAMTGGKFSS GLTGCVRNLS LMNARPGEQP ARPIELQAAA ENGINVGRCS S
//
DBGET integrated database retrieval system