ID A0A1S3LKX3_SALSA Unreviewed; 144 AA.
AC A0A1S3LKX3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Heme transporter hrg1-B {ECO:0000313|RefSeq:XP_013991623.1};
GN Name=LOC106567162 {ECO:0000313|RefSeq:XP_013991623.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_013991623.1};
RN [1] {ECO:0000313|RefSeq:XP_013991623.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_013991623.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=heme b(in) = heme b(out); Xref=Rhea:RHEA:75443,
CC ChEBI:CHEBI:60344; Evidence={ECO:0000256|ARBA:ARBA00035075};
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, phagosome membrane
CC {ECO:0000256|ARBA:ARBA00004265}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004265}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the HRG family. {ECO:0000256|ARBA:ARBA00006203}.
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DR RefSeq; XP_013991623.1; XM_014136148.1.
DR AlphaFoldDB; A0A1S3LKX3; -.
DR PaxDb; 8030-ENSSSAP00000101616; -.
DR GeneID; 106567162; -.
DR KEGG; sasa:106567162; -.
DR CTD; 436697; -.
DR OMA; YLSCIWS; -.
DR OrthoDB; 2914891at2759; -.
DR Proteomes; UP000087266; Chromosome ssa13.
DR Bgee; ENSSSAG00000074896; Expressed in camera-type eye and 16 other cell types or tissues.
DR GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0030670; C:phagocytic vesicle membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015232; F:heme transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR026218; HRG.
DR PANTHER; PTHR31525; HEME TRANSPORTER HRG1; 1.
DR PANTHER; PTHR31525:SF1; HEME TRANSPORTER HRG1; 1.
DR Pfam; PF16954; HRG; 2.
DR PRINTS; PR02095; TRNSPORTRHRG.
PE 3: Inferred from homology;
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 37..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 71..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 107..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 144 AA; 16430 MW; B99D846E7CDAFC51 CRC64;
MGKSRTYISI GYATFGMLVG FSAFLVWNIA YKQPWTAAMG GLSGVLALWA LVTHIMYLQD
YWRTWLKGLK FFIFVAGFFS ILAVVAFATF LTLAITQKQS PTDPTSLYLS CVWSFLTLKW
AFLLALYSHR YRQEFADISI LSDF
//
