ID A0A1S3LLQ7_SALSA Unreviewed; 218 AA.
AC A0A1S3LLQ7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Suppressor of cytokine signaling 2-like {ECO:0000313|RefSeq:XP_013991906.1, ECO:0000313|RefSeq:XP_013991907.1};
GN Name=LOC106567289 {ECO:0000313|RefSeq:XP_013991906.1,
GN ECO:0000313|RefSeq:XP_013991907.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_013991907.1};
RN [1] {ECO:0000313|RefSeq:XP_013991906.1, ECO:0000313|RefSeq:XP_013991907.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_013991906.1,
RC ECO:0000313|RefSeq:XP_013991907.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR RefSeq; XP_013991906.1; XM_014136431.1.
DR RefSeq; XP_013991907.1; XM_014136432.1.
DR STRING; 8030.ENSSSAP00000076470; -.
DR PaxDb; 8030-ENSSSAP00000076470; -.
DR GeneID; 106567289; -.
DR KEGG; sasa:106567289; -.
DR OMA; PQNACVE; -.
DR OrthoDB; 5362214at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000087266; Chromosome ssa13.
DR Bgee; ENSSSAG00000065569; Expressed in liver and 11 other cell types or tissues.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR PANTHER; PTHR10155; PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR10155:SF7; SUPPRESSOR OF CYTOKINE SIGNALING 2; 1.
DR Pfam; PF00017; SH2; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR PRINTS; PR00401; SH2DOMAIN.
DR SMART; SM00252; SH2; 1.
DR SMART; SM00253; SOCS; 1.
DR SMART; SM00969; SOCS_box; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50001; SH2; 1.
DR PROSITE; PS50225; SOCS; 1.
PE 4: Predicted;
KW Growth regulation {ECO:0000256|ARBA:ARBA00022604};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191};
KW Signal transduction inhibitor {ECO:0000256|ARBA:ARBA00022700};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 61..176
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT DOMAIN 171..217
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 218 AA; 24391 MW; 58050326BBD1C20C CRC64;
MPKSSGVPSP SGPMIIPTSA PDKSLNAVRL KDSELEPRRI ESREDAARLQ RAMSHLQESG
WYWGPLTAAQ AKQVLIDAPE GTFLLRDSSY QGYLLTLSVK TSLGPTHLRI EHATGMFGFD
SVIVARPQLR RFEGAVDLVQ HYALTYKHLA TQNDTGGGNH SAPTEKTLQL KLTRPLHKVS
PSLQHLCRIT INQHSHCHQD LPLPRRLQDF MLEYPFVL
//
