ID A0A1S3LLU0_SALSA Unreviewed; 331 AA.
AC A0A1S3LLU0;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Iroquois-class homeodomain protein irx-1-B-like {ECO:0000313|RefSeq:XP_013991937.1};
GN Name=LOC106567327 {ECO:0000313|RefSeq:XP_013991937.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_013991937.1};
RN [1] {ECO:0000313|RefSeq:XP_013991937.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_013991937.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108}.
CC -!- SIMILARITY: Belongs to the TALE/IRO homeobox family.
CC {ECO:0000256|ARBA:ARBA00008446}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_013991937.1; XM_014136462.1.
DR AlphaFoldDB; A0A1S3LLU0; -.
DR STRING; 8030.ENSSSAP00000074736; -.
DR PaxDb; 8030-ENSSSAP00000074736; -.
DR GeneID; 106567327; -.
DR KEGG; sasa:106567327; -.
DR OrthoDB; 2915644at2759; -.
DR Proteomes; UP000087266; Chromosome ssa13.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR008422; Homeobox_KN_domain.
DR InterPro; IPR003893; Iroquois_homeo.
DR PANTHER; PTHR11211:SF41; IROQUOIS HOMEOBOX 7; 1.
DR PANTHER; PTHR11211; IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX; 1.
DR Pfam; PF05920; Homeobox_KN; 1.
DR SMART; SM00389; HOX; 1.
DR SMART; SM00548; IRO; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT DOMAIN 105..168
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 107..169
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 176..272
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 212..262
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 331 AA; 37253 MW; BCCECED19DB91A8E CRC64;
MSASQIGFGN FFFERNINML PGYQIPVLGC QPGVQQQQAP HLAAMAGVPL AYSGLQGYNF
IPYPHYRHIA HMNNSFDLKT VSPYYEALLG RGGPFYPQYR PGATDDPSRV AKVATRESTS
ALKAWLNEHL KNPYPTKGEK IMLAIVTKMS LTQVSTWFAN ARRRLKKENR VSWAFKGKSD
EEEGESDEEK SDGSLQTSAL VDEDEIDLQT VDDKVEDIGH RVDNSTPELV DARLEKQSSD
DHRDSTRAHG ENDVEKSDTE RTSSPSRLGC KDNVECQKPK IWSLAETATS ETVKKPHQSC
HPRSTEMGKF WSEWASRNGL YIPRYTAHDI L
//
