ID A0A1S3LNM3_SALSA Unreviewed; 235 AA.
AC A0A1S3LNM3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 isoform X1 {ECO:0000313|RefSeq:XP_013992583.1};
GN Name=alkbh6 {ECO:0000313|RefSeq:XP_013992583.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_013992583.1};
RN [1] {ECO:0000313|RefSeq:XP_013992583.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_013992583.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|ARBA:ARBA00001954};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the alkB family.
CC {ECO:0000256|ARBA:ARBA00007879}.
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DR RefSeq; XP_013992583.1; XM_014137108.1.
DR AlphaFoldDB; A0A1S3LNM3; -.
DR STRING; 8030.ENSSSAP00000021955; -.
DR PaxDb; 8030-ENSSSAP00000021955; -.
DR Ensembl; ENSSSAT00000245310; ENSSSAP00000159659; ENSSSAG00000011720.
DR GeneID; 106567597; -.
DR KEGG; sasa:106567597; -.
DR CTD; 84964; -.
DR OMA; ILQDEMY; -.
DR OrthoDB; 169579at2759; -.
DR Proteomes; UP000087266; Chromosome ssa13.
DR Bgee; ENSSSAG00000011720; Expressed in camera-type eye and 15 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.590; Alpha-ketoglutarate-dependent dioxygenase AlkB-like; 1.
DR InterPro; IPR027450; AlkB-like.
DR InterPro; IPR037151; AlkB-like_sf.
DR InterPro; IPR032862; ALKBH6.
DR InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR PANTHER; PTHR46030; ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6; 1.
DR PANTHER; PTHR46030:SF1; ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6; 1.
DR Pfam; PF13532; 2OG-FeII_Oxy_2; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS51471; FE2OG_OXY; 1.
PE 3: Inferred from homology;
KW Dioxygenase {ECO:0000256|ARBA:ARBA00022964,
KW ECO:0000313|RefSeq:XP_013992583.1}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT DOMAIN 96..223
FT /note="Fe2OG dioxygenase"
FT /evidence="ECO:0000259|PROSITE:PS51471"
SQ SEQUENCE 235 AA; 26618 MW; BC8953647392B5D9 CRC64;
MEHPCSIFED LERYVVKDAP PTVYYIPDFI TEDEESQLLQ QVYKAPKTKW TQLSNRRLQN
WGGLPRPKGM LGEKLPDWLL KYCERISALG AFAGKTANHV LVNEYKPGEG IMPHEDGPLY
HPTVTTISLG SHTLLDFYRP ISAQELDEVP QTEESRYLLS LLVRPRSLLI LQDDMYQRLL
HGIQGTHHDS LTERVANLLA AGVQPGATLT RGTRVSLTVR HVPIVMKANL LLGRK
//
