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Database: UniProt
Entry: A0A1S3LQF8_SALSA
LinkDB: A0A1S3LQF8_SALSA
Original site: A0A1S3LQF8_SALSA 
ID   A0A1S3LQF8_SALSA        Unreviewed;       534 AA.
AC   A0A1S3LQF8;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   31-JUL-2019, entry version 14.
DE   SubName: Full=G protein-activated inward rectifier potassium channel 4-like isoform X2 {ECO:0000313|RefSeq:XP_013992819.1, ECO:0000313|RefSeq:XP_013992820.1};
GN   Name=LOC106567723 {ECO:0000313|RefSeq:XP_013992819.1,
GN   ECO:0000313|RefSeq:XP_013992820.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii;
OC   Salmoniformes; Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_013992819.1};
RN   [1] {ECO:0000313|RefSeq:XP_013992819.1, ECO:0000313|RefSeq:XP_013992820.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_013992819.1,
RC   ECO:0000313|RefSeq:XP_013992820.1};
RG   RefSeq;
RL   Submitted (JUN-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   RefSeq; XP_013992819.1; XM_014137344.1.
DR   RefSeq; XP_013992820.1; XM_014137345.1.
DR   GeneID; 106567723; -.
DR   OrthoDB; 956263at2759; -.
DR   Proteomes; UP000087266; Genome assembly.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PIRSF; PIRSF005465; GIRK_kir; 1.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000087266};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609, ECO:0000313|RefSeq:XP_013992819.1,
KW   ECO:0000313|RefSeq:XP_013992820.1};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM    245    267       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    322    345       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      211    350       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      357    528       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   REGION       87    113       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      163    198       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS     91    107       Pro-rich. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    166    183       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   SITE        336    336       Role in the control of polyamine-mediated
FT                                channel gating and in the blocking by
FT                                intracellular magnesium.
FT                                {ECO:0000256|PIRSR:PIRSR005465-1}.
SQ   SEQUENCE   534 AA;  60540 MW;  A43DDEAFEAFE626E CRC64;
     MVSTMMCRRV TLHEPHNGDY RSPMRIAPRR NSIPPAKALT GKHLLAYLPR PPPESTRFTP
     YPKKVVAKTN MAVMMLHSRR ASLFPSTNNN FPALPPQPVP SASPQSHPKS PTPHRVVAGL
     ISREVDTGQY IIPTEEPEEP ATAHHAHRRR HLKRFSSRWY SGAPSGGPFD STQSPNQGTS
     GENKPHKPRC KLLGEGRPNY GTANKQRQRY VTKDGKCQVN LGPIEDKSRF LSDIFTTLVD
     LKYRWFLFVF TMCYIVTWVA FAEIYFLDAW LRDDVAHVHD PQWQPCFENV DSFISALLLS
     VESQRTIGYG SRLVTANCME GVVLLMAQSI IGSIIDALMV GCMFVKISRP QKRAQTLIFS
     KHCVISERDE KLCLLFRIGD LRASHMVDAK IRAKLIKSRQ TKEGEFIPLE QSEINLGYDT
     GGDRLLLVEP QTITHVINES SPFWEIGAER LTRERFEIII ILEGIVEASG MTCQARTSYT
     EEEILWGHRF ESCMSLEKGS YRVDHGAFDK TFPVHTLTLS AKEKSDEKED EVLF
//
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