ID A0A1S3LRJ9_SALSA Unreviewed; 624 AA.
AC A0A1S3LRJ9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Transcription factor 7-like 1-B isoform X2 {ECO:0000313|RefSeq:XP_013993450.1};
GN Name=LOC106567996 {ECO:0000313|RefSeq:XP_013993450.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_013993450.1};
RN [1] {ECO:0000313|RefSeq:XP_013993450.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_013993450.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TCF/LEF family.
CC {ECO:0000256|ARBA:ARBA00006569}.
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DR RefSeq; XP_013993450.1; XM_014137975.1.
DR AlphaFoldDB; A0A1S3LRJ9; -.
DR GeneID; 106567996; -.
DR OrthoDB; 4225246at2759; -.
DR Proteomes; UP000087266; Chromosome ssa01.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd21996; HMG-box_TCF7-like; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR Gene3D; 4.10.900.10; TCF3-CBD (Catenin binding domain); 1.
DR InterPro; IPR027397; Catenin-bd_sf.
DR InterPro; IPR013558; CTNNB1-bd_N.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR InterPro; IPR024940; TCF/LEF.
DR PANTHER; PTHR10373; TRANSCRIPTION FACTOR 7 FAMILY MEMBER; 1.
DR PANTHER; PTHR10373:SF25; TRANSCRIPTION FACTOR 7-LIKE 1; 1.
DR Pfam; PF08347; CTNNB1_binding; 1.
DR Pfam; PF00505; HMG_box; 1.
DR SMART; SM00398; HMG; 1.
DR SUPFAM; SSF47095; HMG-box; 1.
DR PROSITE; PS50118; HMG_BOX_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00267}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687}.
FT DOMAIN 329..397
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 329..397
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 1..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 194..219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 303..327
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 390..433
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 447..624
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..47
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..63
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 447..486
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 505..542
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 558..582
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 596..624
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 624 AA; 68662 MW; D5A3C554C40CEB28 CRC64;
MPQLDGGGGD DLGANDELIS FKDEGEQEEK TAENVSSERD LDDVKSSLVN ETENNSSSSD
SEAVSHRRPQ HHIPDWESYV RQREFVAEAL RRQQHDSGLF KASLYAGYPL LMIPDLGNLA
NLGHLGNLGN PYLSPGVLSP GARTYLQMKW PILDVPGTSA LKDPRSPSPA HMSNKVPVVQ
HSHLSPFSPL LSYSPDPFPP RTPPPHLSAD TGLPPTPHPA ELSPYYPLSP GGMEHMTHPL
SWLQGQSMYG IPVGGFRPSY PAALALNSSM SSFVSSRFSP HMVPPPQTSV PHPAIVSTAI
KQEPRDSNQH GRCAVSMGDR EKEEKKPHVK KPLNAFMLYM KEQRPKVVAE CTLKESAAIN
QILGRRWHTL SREEQSKYYD MARKERQLHS QLYPGWSARD NYGKRKKRKR DGRPETAPEG
QMTHLQSAAS EEHFSAQLKK SCVSYGTQER PSVSHTHLTH THLSQASPAS SLDSPATPTT
ALASPAAPAP THTEHTHSHS EHTHPEQVQP LSLTTKPPRL QSHRDTHGQA YTHIQSHTHP
HLLTHTHLPP PPTPNTSSSS SPSSHPPFSL HMNSSSKQTP PLLSRPIPFA SGLAPPTSIH
ESTMSSHHAM LQSQPLSLVT RNNN
//
