ID   A0A1S3LTR0_SALSA        Unreviewed;       716 AA.
AC   A0A1S3LTR0;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Rho GTPase-activating protein 24 isoform X3 {ECO:0000313|RefSeq:XP_013994378.1};
GN   Name=arhgap24 {ECO:0000313|RefSeq:XP_013994378.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_013994378.1};
RN   [1] {ECO:0000313|RefSeq:XP_013994378.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_013994378.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_013994378.1; XM_014138903.1.
DR   AlphaFoldDB; A0A1S3LTR0; -.
DR   GeneID; 106568499; -.
DR   CTD; 83478; -.
DR   OrthoDB; 48967at2759; -.
DR   Proteomes; UP000087266; Chromosome ssa13.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd04390; RhoGAP_ARHGAP22_24_25; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR15228:SF19; RHO GTPASE-ACTIVATING PROTEIN 24; 1.
DR   PANTHER; PTHR15228; SPERMATHECAL PHYSIOLOGY VARIANT; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT   DOMAIN          1..57
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   DOMAIN          67..261
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          293..402
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          410..429
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          511..533
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          551..610
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          695..716
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..17
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        293..340
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        366..402
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        585..610
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   716 AA;  79150 MW;  56E9309DF5FBFDC7 CRC64;
     MEVVQQTVHQ YGSDLPSSPH SGGDRERMTA NHETYLLMAS TQNDMEDWVK TIRRVIWAPF
     GGGIFGQKLE ETVRYERRYG GRQAPMLVEQ CVGFIRKWGL REEGLFRLPG QANLVKELQD
     AFDCGEKPSF DCNTDVHTVA SLLKLYLREL PEPVIPFSKF DEFLSCTKLL SKDEESGMKE
     LKRQVECLPP VNYNLLQYIC RFLDEVQSYS GVNKMSVQNL ATVFGPNILR PKIEDPVAIM
     EGTVLVQQLM SVLIGRHDVL FPRDEDSPKT LELVNNNNEV QKRLTQIVPT VQTTEQNNNT
     QIPQQRVKQC SWETPESPHR QPPVTLDNNG SGSPRSASPL NGHVTGRFDL ARSPPLTVKK
     NPAVSKGSGV VTNGSFSCSP SGDAANQEKS QTLPGNTGGI SGLQVRRTLK GSGTKMGTSG
     VPNGGVRMGV SSTDVVNGTL NGRNGLWVPN GYPVTLRDSK SRDCGEQTVA QNRLSTYDNV
     QQQQQQQLQN QQQPCLSSSC EDKQSVDSAT WSTSSCEISL PDNSTSCRSS TTTCPEQDFY
     GGLGHYQDPL LLLDGPRGLS SLDEQPQPGG DVEGERRNGG GGSGGRGSGA TSSSDNSETF
     PVNKGPSSHS ALHSLVASLK QEMQKQKTEY EARITSLEHS NLELETEMGT LHEELNQEKK
     KVTMVEIKFR NAERAKDDAE KRNEMLQKEM EQFFSTFGDL TDDPRRPSRA NTIWIQ
//