ID A0A1S3LV18_SALSA Unreviewed; 447 AA.
AC A0A1S3LV18;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Inhibin beta A chain-like {ECO:0000313|RefSeq:XP_013994685.1};
GN Name=LOC106568683 {ECO:0000313|RefSeq:XP_013994685.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_013994685.1};
RN [1] {ECO:0000313|RefSeq:XP_013994685.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_013994685.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR RefSeq; XP_013994685.1; XM_014139210.1.
DR AlphaFoldDB; A0A1S3LV18; -.
DR STRING; 8030.ENSSSAP00000091979; -.
DR PaxDb; 8030-ENSSSAP00000091979; -.
DR GeneID; 106568683; -.
DR KEGG; sasa:106568683; -.
DR OMA; GKEEHAH; -.
DR OrthoDB; 3015718at2759; -.
DR Proteomes; UP000087266; Chromosome ssa14.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd19404; TGF_beta_INHBA; 1.
DR Gene3D; 2.60.120.970; -; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF133; INHIBIN BETA A CHAIN; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR PRINTS; PR00669; INHIBINA.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..447
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010204496"
FT DOMAIN 325..447
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
SQ SEQUENCE 447 AA; 49039 MW; D02882B2695FFB57 CRC64;
MPSLAALAGV LALLLARLQT GCGSPTLAGP LAAVDVAMPE QGLVEETQVT HCPSCVLAQM
RRGYDPVPPG FESESESVSL ALAQTSGQTD MVEAVKRHIL NMLHLNARPN VTHPVPRAAL
LNAIKKLHVG RVGEDGRVEI QEEGPGGAGG EWAAPPEPPS EIITFAEPGN SPSAMTFDIS
KEGSELSVVE QANVWLFLKL AKGKGRGKGK VNIQLLQRRR QKLKAPGSAS TFTETQGEEE
ELVSEKMVDT RRSGWHTLPV PRSIQSLLDA GGRVLDLRVS CPLCTEVGAK PILVPTEDEQ
PGCEQEQSHR PFLMVVLRPG KEEHAHRRAR RGLECDDKMH MCCKRQFYVN FKDIGWNDWI
IAPSGYHANY CEGDCPSHVA SITGSSLSFH STVINHYRMR GYTPFQNIKS CCVPTRLRAM
SMLYYNEEQK IIKKDIQNMI VDECGCS
//
