ID A0A1S3LW68_SALSA Unreviewed; 1756 AA.
AC A0A1S3LW68;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Eukaryotic translation initiation factor 4 gamma 1-like isoform X6 {ECO:0000313|RefSeq:XP_013995091.1};
GN Name=LOC106568864 {ECO:0000313|RefSeq:XP_013995091.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_013995091.1};
RN [1] {ECO:0000313|RefSeq:XP_013995091.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_013995091.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the eukaryotic initiation factor 4G family.
CC {ECO:0000256|ARBA:ARBA00005775}.
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DR RefSeq; XP_013995091.1; XM_014139616.1.
DR GeneID; 106568864; -.
DR OrthoDB; 92033at2759; -.
DR Proteomes; UP000087266; Chromosome ssa14.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR CDD; cd11559; W2_eIF4G1_like; 1.
DR Gene3D; 1.25.40.180; -; 3.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR045208; IF4G.
DR InterPro; IPR003891; Initiation_fac_eIF4g_MI.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR InterPro; IPR003307; W2_domain.
DR PANTHER; PTHR23253; EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA; 1.
DR PANTHER; PTHR23253:SF10; EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 1; 1.
DR Pfam; PF02847; MA3; 1.
DR Pfam; PF02854; MIF4G; 1.
DR Pfam; PF02020; W2; 1.
DR SMART; SM00515; eIF5C; 1.
DR SMART; SM00544; MA3; 1.
DR SMART; SM00543; MIF4G; 1.
DR SUPFAM; SSF48371; ARM repeat; 3.
DR PROSITE; PS51366; MI; 1.
DR PROSITE; PS51363; W2; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000313|RefSeq:XP_013995091.1};
KW Protein biosynthesis {ECO:0000313|RefSeq:XP_013995091.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT DOMAIN 1397..1519
FT /note="MI"
FT /evidence="ECO:0000259|PROSITE:PS51366"
FT DOMAIN 1590..1756
FT /note="W2"
FT /evidence="ECO:0000259|PROSITE:PS51363"
FT REGION 1..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 174..425
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 467..704
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 761..804
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 829..851
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1121..1399
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..49
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..79
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 178..193
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 196..210
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 218..249
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 289..311
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 327..351
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 398..425
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 610..639
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 645..659
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 664..679
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1153..1167
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1177..1204
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1263..1285
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1286..1338
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1345..1374
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1756 AA; 190553 MW; 707D2C4C6886E783 CRC64;
MNKPPQPITG PTSVPHPSPS PGLTQAAYAP GQPPSLVFAT PPPQQMNSSP QPRQPYYANR
ATMPTSAPRV QTSSGPRPVG PTHVYQPGSQ MMMIPGQQLS FAGSPQGYFI PPGQYRAPYM
PPSPQYPVTS GTAGFYPGTS PAEYSTYAGA YYPAQPQYSH TPTVQTAPVM ISPAQPQQQA
LPPQPPPSQP PAPKRERIAI RIRDPNQGGR DITEEIMSGG RATSTPPSQS STTEGEGPSQ
TNGEVTKPVT MMTRTDDIME PAVSKAMAAV TPPPALVTPE PATATVPAEA KQETDSQAAP
PTEQVVSQSA VLTAEGKAEE AIPPEEDQAP PTSPSPPAAP TSPPPAEVQT PPPITTIAQV
SDTVDAGVTL AGKAVTPEAP PIEEEPSAAP AAVEKPPALV AEKEEAENKK EEVVVEEEKV
EKVKEEPVLT TKPEVVAPVT VAVAEEHTKP APRPLTPVAK ATIKHSAPAV KPVVSMEAPT
KTESVVEPTA TKRETAAAVP ASAPVPAVTP SVPEAEPAMA QKSEAQTPLS NGLPQEYPDE
VDAPVPAQER TAMPNTEPAA PTPQETATPA AAAVAEEGEK EEKEEDAATV PLASSPSEDT
SMQAAVSVPK KKRNMKELNK KEAIGDMLDA FKEEKEAAAA PEPLSTPAEP SPVAPPPLAT
ADAPDETWEE KEDKQNADTP PLKPGDLKYQ YKGEQWKPID PEDKKRYDRE FLLGFRYIGA
SMNKPEGLPL ICDVVLDKAN KTPMRPAEPG RNMMNAGPDF TPAFMGNLGR QSSGGGGGGP
RGPGRDHMGP PGPRRSQQGQ RKEPRKIIIS SSLGGDVELN KAEKAWKPAV KMAGSRGTGP
DEEESDDPEQ AKTQELFKRV RSILNKLTPQ MFQQLMKQVT ELTIDTEERL KGVIDLIFEK
AISEPNFSVA YANMCRCLMG LKVPTTDKPG VTVNFRKLLL NRCQKEFEKD QDDDVIFEAK
QKEMEAAKEE EKAGLKAELE EAKDKARRRS LGNIKFIGEL FKLKMLTEAI MHDCIVKLLK
NHDEESLECL CRLLSTIGKD LDFEKAKPRM DQYFAQMDKI IKEKKTSSRI RFMLQDVIDL
RRSGWVPRRG EQGPKTIDQI HKDAEREEQM QLVKVQQQLM SRNDSGGGGG GGGGGGGGGG
RGGGGGGGGG GRDGRGGDRD RGGRDQGGRG GQHGGQGARG SQPQDEGWNT VPISTKNRPI
DTSRLSKITK PGALDFNNQL LAPQLGGKGM WGSWGKGSSG GTTGAKPAAG AEPAAETGRP
ATGNRFSALQ QSAPPASSSD ADRRVPQRSS SSRDRGGDRD RFDRFERRDS SRDARPPVTK
RSFSRETEER RSDSRTPTEP PVRRVASMSD DRNRGSRDRG GSGSRDRAPS KEAVVKRETN
PTPPPAAPAK PAMTEEELDK KSSAIIEEYL HLNDMKEALQ CVAELNSAPL LFVFVRNGLE
DTLERSAIAR ERMGLLLHQL LKAGTLPTTQ YYKGLQEILE VAEDMAIDIP HIWQYLAELI
TPMLHDGGIP MGQLFREISK PLVPLGKAGL LLVQILNLLC KGMTHKKVGG LWTEAGLNWR
DFLPEDEDVN KFVTEQKMEF TLGEESDETN QKKPMSGEEL SKHLDRLIQD KANNQRIRDW
VEANLDQQQA AANQFVRALM TSICQSAVIC ENPYKVDVEQ ITQRAKLLQR YLSDEHRELQ
ALYALQALMV HMEQPANLLR MFFDALYDED VIKEEAFYRW ESSKDPAEQT GKGVALKSVT
AFFTWLREAE EESDKD
//
