ID A0A1S3LXK4_SALSA Unreviewed; 1099 AA.
AC A0A1S3LXK4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Suppression of tumorigenicity 18 protein-like isoform X2 {ECO:0000313|RefSeq:XP_013995591.1};
GN Name=LOC106569122 {ECO:0000313|RefSeq:XP_013995591.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_013995591.1};
RN [1] {ECO:0000313|RefSeq:XP_013995591.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_013995591.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the MYT1 family.
CC {ECO:0000256|ARBA:ARBA00010194}.
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DR RefSeq; XP_013995591.1; XM_014140116.1.
DR AlphaFoldDB; A0A1S3LXK4; -.
DR STRING; 8030.ENSSSAP00000030720; -.
DR PaxDb; 8030-ENSSSAP00000030720; -.
DR GeneID; 106569122; -.
DR OMA; RYTCYQE; -.
DR OrthoDB; 3091993at2759; -.
DR Proteomes; UP000087266; Chromosome ssa14.
DR Bgee; ENSSSAG00000039855; Expressed in brain and 4 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 4.10.320.30; -; 6.
DR InterPro; IPR013681; Myelin_TF.
DR InterPro; IPR002515; Znf_C2H2C.
DR InterPro; IPR036060; Znf_C2H2C_sf.
DR PANTHER; PTHR10816; MYELIN TRANSCRIPTION FACTOR 1-RELATED; 1.
DR PANTHER; PTHR10816:SF9; SUPPRESSION OF TUMORIGENICITY 18 PROTEIN; 1.
DR Pfam; PF08474; MYT1; 1.
DR Pfam; PF01530; zf-C2HC; 6.
DR SUPFAM; SSF103637; CCHHC domain; 6.
DR PROSITE; PS51802; ZF_CCHHC; 6.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU01143}.
FT DOMAIN 536..763
FT /note="Myelin transcription factor 1"
FT /evidence="ECO:0000259|Pfam:PF08474"
FT REGION 41..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 220..268
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 281..322
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 664..700
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 739..761
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 978..1033
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 79..100
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 142..156
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 188..207
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 252..268
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 283..322
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1099 AA; 122167 MW; 3E0063CAEEDDFFDC CRC64;
MDSEGEENTL QTCNGGKVPA DCITQAPSTY GSMAARKRLA QEGVQGAPVN KRKSLLMRPR
HYSPSEACCE EENEDLAPPQ DKEELRNIDT PADEYSETLN EPKRNGCQDA ITKPHDSFGW
SEVVTDSPHQ EAAASETLED EEVAERNQEE EEEDQSQDRM SITCSSSPRK SPYGDSWEAD
WEPLSLSHSA RVNGSNGSIS SPSKATTGER YLLGRNDYLH MRDHDPDSVL SGYNMGRAGP
FQAGPLRLYR STPSEEDSEG EPEVERPPRL EAWALGLQEM ERPLSLEMDR GDRDRDRDRG
DRDRDRDRGD KDRDRDRGDR DWDRGRVNLS LLEQAMALQS EQRQVLHNAY REMDRFLLEQ
MTNERRHQRL LDVDTRVGYH GCKDSPRPDK KDIRCPTPGC DGTGHVTGLY PHHRSLSGCP
HKVRVPPEIL AMHENVLKCP TPGCTGRGHV NSNRSTHRSL SGCPIAAAVK VSKPQEESPK
CRQAPERLSS SHFPHQIQQH LVFLDSSPTR PLGPLMKKLE LNQYNYRFAH HHPVAAALQA
NLTKDMDKYS KIRFDYASFD EQVFGKQPLM APNQDQEISS SHFPDSLQYT GFLGAPGNCL
PTPGPVRHSP PSHYKPGGEG LQATTATTAI LNLSTRYRSN MESISGRPLA SSTKDMPIEV
DENGTLDLSM KKGREVKAPP QVPLGDATQS PPESTLSKQA GSVHISPAFY QALCERDTWD
TPLNFSKAQH QIMHDREQED FDDASLEDQS YSGDTSMFSP KTDMLLRDSK KELMSCPTPG
CDGSGHVTGN YASHRSVSGC PLADKTLKSL MAANSQELKC PTPSCDGSGH VTGNYSSHRS
LSGCPRARKG GLKLTPNRDE KDDQEIKCPV TGCDGQGHTS GKYTSHRSAG SCPLAAKRHK
ESSINGLPFP WNKACKQELP HCPLPGCNGL GHANNVFVTH RSLSGCPLNA QSIKKKMTGE
EMMTIKLQAS SVDNNDDVQH MDHEIKELNE SNLKIEADMM QLQTQISSME CNLKTIEEEN
KMIEQHNDSL LKELAHLSQA LINSLTDIQL PQMGPISEHN FEAYVNTLTD MYNSSEHDYS
PECKALLDNI KQAMKGIHV
//
