ID A0A1S3LXY8_SALSA Unreviewed; 796 AA.
AC A0A1S3LXY8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Dipeptidyl aminopeptidase-like protein 6 {ECO:0000256|ARBA:ARBA00040948};
DE AltName: Full=Dipeptidyl peptidase 6 {ECO:0000256|ARBA:ARBA00042016};
DE AltName: Full=Dipeptidyl peptidase VI {ECO:0000256|ARBA:ARBA00041991};
GN Name=LOC106569194 {ECO:0000313|RefSeq:XP_013995778.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_013995778.1};
RN [1] {ECO:0000313|RefSeq:XP_013995778.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_013995778.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_013995778.1; XM_014140303.1.
DR AlphaFoldDB; A0A1S3LXY8; -.
DR GeneID; 106569194; -.
DR OrthoDB; 2876738at2759; -.
DR Proteomes; UP000087266; Chromosome ssa14.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 2.140.10.30; Dipeptidylpeptidase IV, N-terminal domain; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001375; Peptidase_S9.
DR InterPro; IPR002469; Peptidase_S9B_N.
DR PANTHER; PTHR11731:SF20; DIPEPTIDYL AMINOPEPTIDASE-LIKE PROTEIN 6; 1.
DR PANTHER; PTHR11731; PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED; 1.
DR Pfam; PF00930; DPPIV_N; 1.
DR Pfam; PF00326; Peptidase_S9; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
PE 4: Predicted;
KW Aminopeptidase {ECO:0000313|RefSeq:XP_013995778.1};
KW Hydrolase {ECO:0000313|RefSeq:XP_013995778.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000313|RefSeq:XP_013995778.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 34..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 133..497
FT /note="Dipeptidylpeptidase IV N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00930"
FT DOMAIN 580..780
FT /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00326"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 796 AA; 90304 MW; 6FF75C60A432B5AC CRC64;
MNSSAGASNY RRGSTKGEKD LVGSAPPQRN WKGIVIALLV ICIILSLIVT SVILLTPIAD
DSLALKKKVT IEDVFGGDLH VHDPDATWLS DNVLLYRTRE GDVVKLNIET QERVILVENR
KFEMFKATKY HISPDLEHVL LAYNVAPVYQ HSYMAFYIIC SLITPETWSL NPPEVRNAPL
QYAGWGPKGQ QLIFIFENNI YYRATVESRT IRLVSTGKER VIFNGLSDWL YEEEILQTHI
AHWWSPDGLR LAYATINDTL VPKMEVPIFT GAPYPIGLEY HYPKAGEENP VIHLSVVSLN
GPLHTVEMKK PDDPRIGMEY YITMVMWATT TKLAVNWLNR AQNNSILTLC EATTGVCTKK
HEDESDSWLH KQNEAPLFSH DGYKFFFTRA IPQGGRGKFF HISMSTSQPN TSTDTLQSLT
SGDWDVTQIL AYSQDKQLIY FLSTEDDPKR RHLYSADTKG PFNRRCLSCE FKCGYVDGSF
SHNMQYFLLN CKGPDVPSVA IYSTKDRQKV LDLETNEGVN NTYHNMQMPK VEYETITIDD
YTLTMQILKP AGFIDTAHYP LLLLVDGTPG GQMVTEQFRV DWATVLVSSY STIVIRFDGH
GSGFQGTNLL HRIRRKLGVI EERDQMEALR LISKEMYIDK SRIGVYGKVY GGYLATLLLS
AEDSLLKCGA AVSPITDFKL YASAFSERYL GSPKTDSRVY SVASLAHRAA HLMDRKYMII
HPTADEKVHF QHSAKFINHL INEKANYSLQ IYPDEGHFLH SDGTRQHLSQ SLVNFFEECF
RLPDLPSEDK EDEGDV
//
