ID A0A1S3M160_SALSA Unreviewed; 582 AA.
AC A0A1S3M160;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Low-density lipoprotein receptor-related protein 12-like {ECO:0000313|RefSeq:XP_013996875.1};
GN Name=LOC106569782 {ECO:0000313|RefSeq:XP_013996875.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_013996875.1};
RN [1] {ECO:0000313|RefSeq:XP_013996875.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_013996875.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane, coated pit
CC {ECO:0000256|ARBA:ARBA00037878}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00124}.
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DR RefSeq; XP_013996875.1; XM_014141400.1.
DR AlphaFoldDB; A0A1S3M160; -.
DR PaxDb; 8030-ENSSSAP00000094951; -.
DR KEGG; sasa:106569782; -.
DR OrthoDB; 2916406at2759; -.
DR Proteomes; UP000087266; Chromosome ssa14.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00041; CUB; 1.
DR CDD; cd00112; LDLa; 2.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 3.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 1.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR PANTHER; PTHR24270; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED; 1.
DR PANTHER; PTHR24270:SF47; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 12; 1.
DR Pfam; PF00431; CUB; 1.
DR Pfam; PF00057; Ldl_recept_a; 2.
DR PRINTS; PR00261; LDLRECEPTOR.
DR SMART; SM00192; LDLa; 3.
DR SUPFAM; SSF57424; LDL receptor-like module; 3.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 1.
DR PROSITE; PS01209; LDLRA_1; 1.
DR PROSITE; PS50068; LDLRA_2; 3.
PE 4: Predicted;
KW Coated pit {ECO:0000256|ARBA:ARBA00023176};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; Lipoprotein {ECO:0000313|RefSeq:XP_013996875.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|RefSeq:XP_013996875.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 192..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 9..68
FT /note="CUB"
FT /evidence="ECO:0000259|Pfam:PF00431"
FT REGION 319..381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 393..428
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 461..490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 319..338
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 340..366
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 475..490
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 94..109
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 132..147
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 150..162
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 157..175
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 169..184
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
SQ SEQUENCE 582 AA; 63083 MW; DDAF7FC8C6C1D7A6 CRC64;
MDFKLDGTGY GDYVKVYDGL EENPRLLLRV LTAFDSRAPV AVVSSSGQLR VHFYADKINA
ARGFNVTYQV DGFCLPWEIP CGGNWGCYTG QQRCDGYWHC PNGRDEVNCS ICQEDEFPCS
RNGACYPRSD RCNYQNRCPN GSDEKNCFFC QPGNFHCKNN RCVFESWVCD AQDDCGDGSD
EESCPVIVPT RVITAAVIGS LICGLLLVIA LGCTCKLYSL RMFERRSFET QLSRVEAELL
RREAPPSYGQ LIAQGLIPPV EDFPVCSGNQ VSVLESLRLA VRSQLGFTSI CLPTSGRHSN
IWRRLFNFTR SRRSGSLALV SADAEDQNTS SGNGGSSVRE PERTEPHRGL LPLDSDDTDT
ESERRDVPGA MGGLVAPLPA KTPPATAVEA ISVSTSSTTP APLPSSRNRH RASPGVVETH
TMDTPGGEAA EPQCALVGRS QLSSALNRVT RTLRWVRFSL GRSGDSSGGA THNHSPLRHL
EHGAGTREDE DDVELLIPLS DAASDTDSTN EASRLLNLEL GPDQAACRLS SPASLGSGRV
SLGRDGPCEH CNIVHTAQIP DTCLEATGKT ETNGDDELLL LC
//
