ID   A0A1S3M6X4_SALSA        Unreviewed;       999 AA.
AC   A0A1S3M6X4;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=DENN domain-containing protein 1A-like isoform X4 {ECO:0000313|RefSeq:XP_013998947.1};
GN   Name=LOC106570883 {ECO:0000313|RefSeq:XP_013998947.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_013998947.1};
RN   [1] {ECO:0000313|RefSeq:XP_013998947.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_013998947.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_013998947.1; XM_014143472.1.
DR   AlphaFoldDB; A0A1S3M6X4; -.
DR   GeneID; 106570883; -.
DR   CTD; 57706; -.
DR   OrthoDB; 5398783at2759; -.
DR   Proteomes; UP000087266; Chromosome ssa01.
DR   GO; GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.450.200; -; 1.
DR   Gene3D; 3.40.50.11500; -; 1.
DR   Gene3D; 6.10.140.1000; -; 1.
DR   InterPro; IPR001194; cDENN_dom.
DR   InterPro; IPR005112; dDENN_dom.
DR   InterPro; IPR043153; DENN_C.
DR   InterPro; IPR040032; DENND1A/B/C.
DR   InterPro; IPR037516; Tripartite_DENN.
DR   InterPro; IPR005113; uDENN_dom.
DR   PANTHER; PTHR13196; DENN DOMAIN-CONTAINING; 1.
DR   PANTHER; PTHR13196:SF22; DENN DOMAIN-CONTAINING PROTEIN 1A; 1.
DR   Pfam; PF03455; dDENN; 1.
DR   Pfam; PF02141; DENN; 1.
DR   Pfam; PF03456; uDENN; 1.
DR   SMART; SM00801; dDENN; 1.
DR   SMART; SM00799; DENN; 1.
DR   SMART; SM00800; uDENN; 1.
DR   PROSITE; PS50211; DENN; 1.
PE   4: Predicted;
KW   Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW   Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT   DOMAIN          13..375
FT                   /note="UDENN"
FT                   /evidence="ECO:0000259|PROSITE:PS50211"
FT   REGION          453..581
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          652..755
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          786..845
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          900..999
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        453..486
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        487..501
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        509..525
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        789..816
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        817..840
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        921..943
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        985..999
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   999 AA;  109666 MW;  0AC7376F8E84064D CRC64;
     MGSRIKDNPE ATFEVYLEVT HPGTTGSDPE VRRRFPEDYI DQETLQTVPK FCFPFSVDSL
     SVSQVGQNFT FVLTDIESKQ RFGFCRLSSG AHSCYCILSY LPWFEVFYKL LNILADFTIK
     GQESQWRELL ESLHTLPIPD PGVPVHLSVH SYFTVPDRRE LPSIPENRNL TEYFVAVDVN
     NMLHLYASML YERRILICCS KLSTLTACVH GSAAMMYPMY WQHVYIPVLP QHLIDYCCAP
     MPYLIGVHSS LMEKVRGMAL DDVVVLNVDT NTLETPFDDL QSLPNDVVSS LKNRLKKVST
     TTGDGVARAF LKTQAALFGC YRNALQIQPG EPITFSEEVF VTHRSSAMRQ FLQNAIQLQL
     FKQFIDGRLD LLNAGEGFSD VFEDEINTGE YAGSDKNYHQ WLFTVKKGGG AIFNTVRTKA
     NPAMKTVYKF AKDHARMGIK EVKSRLKQKE LAENGYSSTV GTGGTGTGTG EEGTTAGSPT
     STDGKDGSAR TWDERRPITV HFGQPLREPP TRPTRPPPPR LQCGNSRPAR PPRPQVAKRP
     RSNVGLESSP EQPPPYRSLK EAEEGEEPIS GPSYTAPPSP VMEKFADINL LGNMFSCLDE
     PEGQQLSLAK SLEDLRTPKD PQEQQKLIYQ RMDLSGTLPG LKHSNPYNKM WSMHGQDDMA
     MSGRVSPNWD RPLSVPPPDL EELRPPSRES FGPGVLERPD LFTTPSQGEC ITIPRPQGRK
     TPEPGKVLGP PPVPQPRTKP GVVGDGGTTT AGGQEFRQAL GMGGDLMLQP TKMDFNDGED
     VDLLSLLDPL NNPAQTTTTP ALAGEGADSR SSAEPPSSRP VLPPRPYPQS LPPFHQHMPL
     NPFTPPLGYS THRHYSPTVA GNPFGSGAYG PPASAYFHAS PHGHPPHPLS TMPGLYRLSS
     PVGSNLPPGM GSMRSAFPNH GGPPPTSSGS HHALSNLLDS PSAPTPSLAP RVLPKPPNTA
     EDSNETQDPF GDLLAMAKPA AAPPKKKVEG LRGKWETFD
//