ID A0A1S3MA96_SALSA Unreviewed; 630 AA.
AC A0A1S3MA96;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Atypical kinase COQ8A, mitochondrial {ECO:0000256|ARBA:ARBA00018535};
DE AltName: Full=Chaperone activity of bc1 complex-like {ECO:0000256|ARBA:ARBA00032726};
DE AltName: Full=Coenzyme Q protein 8A {ECO:0000256|ARBA:ARBA00033204};
DE AltName: Full=aarF domain-containing protein kinase 3 {ECO:0000256|ARBA:ARBA00031775};
GN Name=LOC106571434 {ECO:0000313|RefSeq:XP_014000005.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014000005.1};
RN [1] {ECO:0000313|RefSeq:XP_014000005.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014000005.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004749}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. ADCK protein
CC kinase family. {ECO:0000256|ARBA:ARBA00009670}.
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DR RefSeq; XP_014000005.1; XM_014144530.1.
DR AlphaFoldDB; A0A1S3MA96; -.
DR STRING; 8030.ENSSSAP00000098909; -.
DR PaxDb; 8030-ENSSSAP00000098909; -.
DR GeneID; 106571434; -.
DR OrthoDB; 668390at2759; -.
DR UniPathway; UPA00232; -.
DR Proteomes; UP000087266; Chromosome ssa15.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd13970; ABC1_ADCK3; 1.
DR InterPro; IPR004147; ABC1_dom.
DR InterPro; IPR034646; ADCK3_dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR43851; -; 1.
DR PANTHER; PTHR43851:SF1; ATYPICAL KINASE COQ8A, MITOCHONDRIAL; 1.
DR Pfam; PF03109; ABC1; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|RefSeq:XP_014000005.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Transferase {ECO:0000313|RefSeq:XP_014000005.1}.
FT DOMAIN 280..519
FT /note="ABC1 atypical kinase-like"
FT /evidence="ECO:0000259|Pfam:PF03109"
FT REGION 48..111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 165..186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 630 AA; 70427 MW; A4DD43BBD3073B21 CRC64;
MAGDMMLVMR GLTKLSQAIM ETQANTLRNG GAQAMAQSMG VAMQKMQEFG GQQQQSASDD
FPADMDSKYD FSGAEGSNMD SGEHVGSGFR DEGGFSSEGT ESADGATSGT YNGQVSVKSK
LFEGYKDPSS QFSGQIRSYR SYSSYRSYHQ DSSGVGGLTA EDMEKAREAK RNEKPHKQML
SERARERKVP VTRLGRLANF GGLAVGLGFG ALAEVAKKSM RPTDKKAVLD SSPFLSEANA
ERIVRTLCKV RGAALKLGQM LSIQDDAFIN PQLAKIFERV RQSADFMPIK QMTKSINNDL
GPNWRDKLES FEERPFAAAS IGQVHLAKMK NGKEVAMKIQ YPGVAKSIDS DVNNLMTLLT
MSNALPEGLF PEHLIEVMSR ELALECDYIR EAKCAKKFKE LLKDHPFFYV PDVIDELSSN
AVLTTELVPG FPLDQAEQLS QELKNEICEN ILKLCLRELF EFRYMQTDPN WSNFFYDPQT
HRVALLDFGA TRGFSEDFTD IYIELIKSAA EGDREGVLKR SRDMKFLTGY ESKSMENAHV
DAVMILGEAF ASTEPFNFGA QSTTERIHNL IPVMLKQRLT PPPEETYSLH RKMGGSFLIC
SRLDAKLSCK NMFQEAYNNY WRDRPNRPSQ
//
